Page 206 - Clinical Hematology Atlas

190 SECTION FOUR LEUKOCYTES

B CELL PROLYMPHOCYTIC LEUKEMIA

A B
FIGURE 19–2A (PB 3500). FIGURE 19–2B (PB 31000).

C D
FIGURE 19–2C (BM 3500). FIGURE 19–2D (BM 31000).
MORPHOLOGY
Peripheral Blood: Medium-sized cells (approximately twice the size of small lymphocyte), one promi-
nent nucleolus, moderately condensed chromatin; small-to-moderate slightly basophilic cytoplasm
9
Absolute lymphocytosis, usually .100 3 10 /L
Anemia
Thrombocytopenia
Bone Marrow: Predominantly prolymphocytes with few residual hematopoietic cells
IMMUNOPHENOTYPE
CD20 , CD19 , FMC7 1
1
1