Page 243 - Clinical Hematology Atlas

CHAPTER 24 BODY FLUIDS 227

CELLS SOMETIMES FOUND IN CEREBROSPINAL FLUID

FIGURE 24–5 Reactive lymphocytes (CSF 31000). FIGURE 24–6 Acute lymphoblastic leukemia
(CSF 31000).

Reactive lymphocytes (Figure 24-5) are associated Blasts in the CSF may have some of the
with viral meningitis and other antigenic stimulation. characteristics of the acute lymphoblastic leukemia
The cells will vary in size; nuclear shape may be (ALL) blasts seen in the peripheral blood (Figure 24-6;
irregular and cytoplasm may be scant to abundant see Chapter 16). It is not unusual for ALL to have
with pale to intense staining characteristics. (See CNS involvement, and blasts may be present in the
description of reactive lymphocytes, Figure 14-7.) CSF before being observed in the peripheral blood.