Page 928 - Textbook of Pathology, 6th Edition
P. 928
912 risk factors in, 620 secondary systemic (reactive), 36 Anaphase lag, 258
steatosis, 621-22 senile, 37 Anaphylactic reaction, 73-76
Alcoholism, 238-40, 620 spleen, 90-91 Anaphylatoxins, 136, 137f
Aldosterone, 98, 686-87, 796 staining, characteristics of, 87-88 Anaplasia, 197-99
Alizarin red S, 13t, 51 systemic, 86-87 Anasarca, 96
Alkaline phosphatase, 595, 830 transthyretin in, 83, 87 Anatomy, morbid, 7
Alkalosis, 104 tumour-forming, 87 Androblastoma,
metabolic, 104 Amyotropic lateral sclerosis, 857 ovary, 749
respiratory, 104 Anaemia of blood loss, 294-95 testis, 713
Alkaptonuria, 40-41 Anaemia of chronic disorders, 302-03 Anencephaly, 256
Allergic vasculitis, 47f, 402-03 Anaemia, aplastic, 325-26 Aneuploidy, 258
Allergy, 66, 141 causes of, 325t Aneurysmal bone cyst, 839f, 840
Allograft, 65 clinical features of, 325 Aneurysms, 405-09
Alpha-1 antitrypsin deficiency, etiology and classification of, 325 atherosclerotic, 406
cirrhosis in, 628-29 laboratory findings in, 325-26 berry, 406, 882
emphysema, 479-80 treatment of, 326 classification of, 405
Alpha-foetoprotein (AFP), 234, 636 Anaemia, Cooley’s, 320 definition of, 405
Alpha-protease inhibitor, 479-80 Anaemia, Fanconi’s, 325 dissecting, 407-08
Alport’s syndrome, 678 Anaemia, general considerations, 291-95 syphilitic (luetic), 406-07
Alternate pathway disease, 664 classification of, 294t Angiitis, 400-05
Altitude, high, 123 clinical features of, 291-92 Angina pectoris, 429
Alveolar proteinosis, 494-95 investigations of, 292-94 Angina preinfarction, 429
Alveolar septa, 461 pathophysiology of, 291 Angina, Ludwig’s, 517
Alveolar soft part sarcoma, 869 Anaemia, haemolytic, 310-24 Angina, Vincent, 517
Alzheimer’s disease, 37, 884 acquired (extracorpuscular), 311-14 Angiodysplasia, 581
Amaurosis, 262 autoimmune (AIHA), 312-13 Angiofibroma, nasopharyngeal, 518
Ameloblastoma, 531-32 classification of, 311t Angiogenesis, 167, 199
malignant, 532 cold antibody, 312-13
American Joint Committee (AJC) staging, 205, congenital, 314-24 Angiomyolipoma, 694
861 definition of, 310 Angioneurotic oedema, 76, 97, 770
Ames’ test, 220 drug-induced AIHA, 313 Angioplasty,
Aminotransferase, 595, 898t extracorpuscular, 311-14 balloon, 459-60
Amniotic fluid embolism, 123-24 general features of, 311 Angiosarcoma, 414, 633
Amoebiasis, 187-88, 580t Heinz body, 317, 320 Angiotensin, 98, 686-87, 796
Amoeboma, 188 hereditary (intracorpuscular), 314-24 Anisocytosis, 197, 292
Ampulla of Vater, carcinoma of, 592 immunohaemolytic, 312-13 Anisonucleosis, 198
Amyloidosis, 82-92 in direct toxic effects, 313-14 Anitschkow cells, 440
AA protein, 83-84 in splenomegaly, 314 Ankyrin, 315
AL protein, 82-83 intracorpuscular, 314-24 Ann Arbor staging, 372t
alimentary tract, 92 isoimmune, 311t, 340-41 in Hodgkin’s disease, 372-73
biopsy in, 88 microangiopathic, 313 in non-Hodgkin’s lymphoma, 380
cardiac, 87, 90 red cell membrane defects, 314-16 Annexin V, 48
chemical nature of, 82-83 warm antibody, 312 Anoxia, brain, 45, 879-81
classification of, 85-87 Anaemia, haemorrhagic, 294-95 Anthracosis, 43, 44f, 488
INDEX
diagnosis of, 88 Anaemia, hypochromic, 295-300, 302t Anthrax, 178
dialysis-associated, 86-87 Anaemia, iron deficiency, 295-300 Anti D, 339
endocrine, 87 bone marrow findings in, 299-300 Antibody, 61
enhancing factor (AEF), 84f, 85 clinical features of, 298-99 Antibody-dependent cell-mediated cytotoxicity
fibril proteins in, 82-83 etiology of, 297-98 (ADCC), 64, 229-30
glycosaminoglycans, 83 iron metabolism in, 295-96 Antidiuretic hormone (ADH), 98, 794
haemodialysis-associated, 86-87 laboratory findings in, 299-300 Anti-endothelial cell antibodies (AECAs), 402
heart, 87, 90 pathogenesis of, 296-97 Anti-GBM disease, 664
heredofamilial, 87 treatment of, 300 Anti-heart antibodies, 436
immunohistochemistry in, 88 Anaemia, Mediterranean, 320-24 Anti-neutrophilic cytoplasmic antibodies
in diabetes mellitus, 822f Anaemia, megaloblastic, 303-10 (ANCAs), 402
in leprosy, 86 biochemical basis of, 305 Anti-oncogenes, 212-14, 213t
in medullary carcinoma, biochemical findings in, 307 versus oncogenes, 214t
thyroid, 87, 813-14, 815f bone marrow findings in, 307 Antigen, 61
in tuberculosis, 86 clinical features of, 306 tumour, 229
kidneys, 89-90 etiology and classification of, 305-06, 305t tumour-associated, 229
liver, 90-91 laboratory findings in, 306-09 tumour specific, 229
localised, 87 treatment of, 309 Antigen-antibody complex, 61, 662-64
metachromasia in, 87-88 Anaemia, microcytic hypochromic, 294t, 299 Antinuclear antibodies (ANAs), 78
morphologic features of, 88-92 Anaemia, myelophthisic, 326 Antioxidants, 33
non-fibrillar components in, 83 Anaemia, normocytic and normochromic, 294t, Antisperm antibodies, 76
physical nature of, 82-83 302 Antithiamines, 252
P-component of, 83 Anaemia, pernicious, 309-10 Antithrombotic factors, 114
pathogenesis of, 83 Anaemia, sideroblastic, 300-02 Antoni A and B, 893
polarising microscopy in, 89f, 91f, 813-14 classification of, 301 Aortic arch syndrome, 404
primary systemic, 86 Anal canal, tumours of, 589-90 Aortic atheroma versus
prion proteins in, 83, 878-79 Anal fissure, 581 syphilitic aortitis, 402t
