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Biology STPM  Chapter 3 Membrane Structure and Transport

                   Section  C    Essay Questions

                Question 11
                   (a)  With the aid of a large labelled diagram, describe the structure of a cell
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                      membrane.                                               [8]
                   (b)  Explain the function of the various types of membrane proteins.   [7]
                                                                        (15 marks)   Semester

                Answer :                                                             1
                   (a)  –  The model for cell membrane is the fluid-mosaic model by Singer
                          and Nicholson in 1972.
                       –  The cell membrane is a dynamic structure that consists of  a
                          phospholipid bilayer with protein molecules that float on or within
                          the membrane.
                       –  The non-polar long hydrocarbon tails are hydrophobic and face
                          inwards and are attracted to one another by hydrophobic interactions
                          and van der Waals forces.
                       –  The polar phospholipid heads are hydrophilic, face outwards and are
                          attracted to the water in the cell and the outer aqueous surrounding.
                       –  The protein molecules are scattered between phospholipid molecules
                          forming a mosaic pattern.
                       –  Extinsic proteins are on the outer and inner surfaces of the membrane.
                       –  Intrinsic proteins are proteins that are partially embedded or
                          penetrate the membrane (integral or transmembrane protein).
                       –  The phospholipid membrane is fluid because the phospholipid
                          molecules and some protein molecules can move laterally or change
                          places.
                       –  Unsaturated fatty acids have double bonds which form kinks. These
                          prevent close packing of the phospholipid molecules, thus increase
                          the membrane fluidity.
                       –  Short, branched carbohydrate chains bind to proteins to form
                          glycoproteins and those that bind to lipids form glycolipids. These
                          are important for cell recognition.
                       –  There are cholesterol molecules between some phospholipid
                          molecules.
                       –  These  molecules  help  to  stabilise  the  membrane  structure    and
                          regulate membrane fluidity.
                       –  The membrane is supported by interacellular protein filaments at the
                          inner surface, which act as a cytoskeleton.







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