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Anatomy of anal sphincter complex

                         The anal sphincter complex is a multilayered cylindrical structure with the innermost layer
                  being  the  anal  lining,  with  the  subsequent  layers:  internal  sphincter,  the  fat-containing

                  intersphincteric space with the longitudinal layer, and subsequently the outer striated muscle

                  layer.  The internal anal sphincter is a smooth muscle in a state of continuous maximal contraction

                  and  represents  a  natural  barrier  to  the  involuntary  loss  of  stool  and  gas.    The  external  anal
                  sphincter is subdivided into two parts, deep (deep sphincter and puborectalis) and superficial

                  (subcutaneous and superficial sphincter). (3)   Endosonographically, the IAS is a 2 to 3 mm-thick

                  circular band and shows a uniform hypoechogenicity.  The average thickness of EAS in females is

                               (4)
                  7.7 + 1.1 mm.


                  Impact of OASIS

                         Severe perineal tears after vaginal birth including anal sphincter complex injuries can have

                  serious short and long-term consequences for the health and well-being of women.  OASIS are
                  commonly associated with increased risk of pelvic floor injury, urinary and anal incontinence, pain

                  and sexual dysfunction.  These symptoms may persist or be present many years after giving birth.

                  In the immediate postpartum period, complications include bleeding from the laceration site,

                  increased pain, wound infection, wound breakdown, and healing abnormalities that may require
                                                     (5)
                  subsequent  surgical  intervention.   Bowel  control  issues,  such  as  fecal  urgency,  anal
                  incontinence, and perineal-rectal and rectovaginal fistula formation are also significant long-term

                  consequences. (6-8)   Based on a recent systematic review and meta-analysis, 19% of women who

                  delivered vaginally experienced anal incontinence (95% CI, 14-25). Following primary repair of
                  OASIS,  55%  (46-63)  had  persistent  sphincter  defect  with  38%  experiencing anal incontinence

                  (95% CI, 33-43).  In addition, women who had sphincter defect diagnosed on ultrasound following

                  a  vaginal delivery  were  4-times  more  likely  to have  anal  incontinence  than  those  with  intact

                  sphincter (RR 3.74, 95 % CI 2.17-6.45). (2)   Given their significant consequences; OASIS prediction,
                  prevention, diagnosis and management are critical.








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