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412                           DEMPWOLF & SHNEIDERMAN



        •  Do regions with higher innovation network      medical devices because they are regulated and
         density innovate faster? What network struc-     tested by product name. Otherwise, prod-
         tures are associated with faster innovation?     ucts are typically not identified in STI data
                                                      sources. One data source that associates product
        Both are active research questions for the authors.      names with the firms that produce them is the
      Regarding accelerators, a 2014 study of innovation      UPC database. The dates associated with UPC
      accelerators for the U.S. Small Business Adminis-     records are the date the record was last updated
      tration found no good metrics in the literature that      rather than the date of product launch, but the
      answered the question of whether accelerators did      source is worth further investigation.
      indeed accelerate innovation (7). A subsequent     2.  STI data resides in multiple unlinked admin-
      network analysis comparing outcomes between 77      istrative databases, and data quality is vari-
      accelerator-affiliated start-ups and 77 non-accelera-     able. Data cleaning, matching, and disambigu-
      tor-affiliated start-ups receiving angel funding found      ation is a significant, time-consuming, and
      that the accelerator subnetwork was 8.5 times larger       ongoing task. Records are not always complete,
      than the unaffiliated angel network and exhibited      and augmentation may be necessary. Efforts
      more opportunity for brokerage. Accelerators invested   to automate data preparation processes through
      33% less per start-up in angel funding ($100,000 vs.      machine learning and other algorithms are
      $150,000) and 50% less overall ($1.3 billion vs. $2.6      underway, but this will still take time.
      billion) than unaffiliated angels. Combined, their     3.  Innovation processes comprise many differ-
      start-ups raised an additional $41 billion in subse-     ent events, and those events may involve dif-
      quent funding rounds and acquisitions (7). While      ferent networks of people and organizations.
      these results suggest that accelerator-affiliated start-     Finding the relationships among events is not
      ups may be more efficient, they do not answer the      always easy.
      question of whether the accelerator-related start-ups     4.  Technology topics have not been standardized
      achieved those results faster than non-accelerator   across the various types of events although there
      start-ups. A pending EventFlow offers the poten-     have been numerous advances in topical anal-
      tial to answer that question using the same dataset      ysis and natural language processing.
      (CrunchBase) as the 2014 study.               5.  Data remains incomplete.
        The question of whether regions with higher net-    6.  FDA drug databases and medical device data-
      work density innovate faster was recently embedded      bases are structured differently and contain
      in a successful funding application for the National      different information. For example, medical
      Institute for Innovation in Manufacturing Biophar-      devices may be linked to clinical trials, but
      maceuticals (NIIMBL) under the National Institute   there are no linkages between drugs and clinical
      of Standards and Technology. The authors will use   trials. Drugs may be linked to patents, but there
      EventFlow and NodeXL to model the network struc-     are no linkages between medical devices and
      ture and innovation outcomes of NIIMBL partners      patents.
      and others in multiple regions throughout the U.S.     7.  Applying this methodology to other critical
      over the next five years to answer this and other      industry sectors may be useful. Clean technol-
      related questions.
                                                     ogy and energy, for example, share many sim-
                                                     ilarities with medical devices in terms of
      CURRENT DATA LIMITATIONS                       inputs, outputs, innovation trajectories, regu-
        As promising as the preliminary results are, several      lations, and challenges. The Lab-to-Market
      data limitations are hindering broader application of   initiative and the Department of Energy’s Office
      this temporal analysis technology to understanding      of Energy Efficiency and Renewable Energy
      and measuring innovation processes:            may offer comparable data to help overcome

        1.  Data is typically not collected or organized       the identified data challenges.
          around products as the end result of innova-
         tion. Product data is available for drugs and
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