Page 26 - FMT April

Processing

production of AHLs signal molecules
and their receptor proteins. The
LuxI/LuxR two-component system

of V. fischeri is considered as the
model system for Gram-negative
bacterial QS and played important
role in luminescence phenomenon
(Zhang et al., 2019) (Figure 2b).

The AI-2 signaling in the bacterial
strains is catalyzed by enzyme
LuxS synthase. LuxS synthase
is also involved in the methyl
cycle activation and reported to
control expression of 400 more
genes associated with bacterial
physiological processes, such as
surface adhesion, motility and
toxin production (Zhang et al., 2019)
(Figure 2c). Figure 2c: The AI-2 mediated quorum sensing pathway of Vibrio harveyi

References
Abisado, R.G., Benomar, S., Klaus, J.R., Zhang, J., Feng, T., Wang, J., Wang, Y. and
Dandekar, A.A. and Chandler, J.R., 2018. Zhang, X.H., 2019. The mechanisms and * Author is Department of Veterinary
Bacterial quorum sensing and microbial applications of quorum sensing (QS) Public Health and Epidemiology, Lala
community interactions. mBio, 9: and quorum quenching (QQ). Journal of Lajpat Rai University of Veterinary
e02331-17. doi:10.1128/mBio.02331-17. Ocean University of China, 18: 1427-1442.
doi: 10.1007/s11802-019-4073-5. and Animal Sciences, Hisar, Haryana-
Jiang, Q., Chen, J., Yang, C., Yin, Y. 125004
and Yao, K., 2019. Quorum sensing: Zhao, X., Yu, Z. and Ding, T., 2020.
a prospective therapeutic target Quorum-Sensing Regulation of ** Centre for One Health, Guru Angad
for bacterial diseases. BioMed Antimicrobial Resistance in Bacteria. Dev Veterinary and Animal Sciences
Research International, 2019: 1-15. doi: Microorganisms, 8:425-450. doi:10.3390/ University, Ludhiana, Punjab- 141004
10.1155/2019/2015978. microorganisms8030425.