Page 46 - Teknik Menjawab Soalan PSPM Biologi

14.3 Inhibitor: A substance that reduce the rate of enzyme reaction

Competitive Inhibitor Non competitive Inhibitor

A : active site A : active site
D : competitive inhibitor B : allosteric site
E : substrate C : non competitive inhibitor

-Competitive inhibitors have similar -Non competitive inhibitors have different
structure with substrate
structure with substrate -It binds to the allosteric site of enzyme
-It competes with substrate to bind -This will cause shape of active site is altered

to the active site of enzyme -Substrate cannot bind to the active site as

-The effect of competitive inhibitor long as non competitive inhibitors bind to
allosteric site
can be overcome -The activity of enzyme is restored to normal

-By increasing the concentration of when the inhibitor is removed

substrate -The effect of non competitive inhibitor
cannot be overcome