Page 8 - Canine Parvovirus Type 2 (CPV-2) and Canine Parvoviral Enteritis
P. 8
Niche in the environment and in host
• Stable to adverse environmental influences
• Resists to heat and extreme pH (pH 3-9)
• Found in the environment such as park, vet clinic and kennels
• Replicate in the nucleus of rapidly dividing host cells
• Lymphoid tissue, such as thymus, lymph nodes, and bone marrow are also
site of replication
• can be isolated from the lungs, spleen, liver, kidney, and myocardium
