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160         SEcTioN ii    Microbiology  ` microbiology—Parasitology                                                                                               Microbiology  ` microbiology—Parasitology





               Cestodes (tapeworms)
                orgaNism             Disease                     traNsmissioN                treatmeNt
                Taenia solium  A     Intestinal tapeworm         Ingestion of larvae encysted in   Praziquantel
                                                                  undercooked pork
                                     Cysticercosis,              Ingestion of eggs in food   Praziquantel; albendazole for
                                       neurocysticercosis (cystic   contaminated with human   neurocysticercosis
                                       CNS lesions, seizures)  B  feces
                Diphyllobothrium     Vitamin B 12  deficiency    Ingestion of larvae in raw   Praziquantel
                 latum                 (tapeworm competes for B 12    freshwater fish
                                      in intestine) Ž megaloblastic
                                      anemia
                Echinococcus         Hydatid cysts  D (“eggshell   Ingestion of eggs in food   Albendazole
                 granulosus  C         calcification”) in liver  E ; cyst   contaminated with dog feces
                                      rupture can cause anaphylaxis Sheep are an intermediate host

               A                    B                    C                    D                    E
                                                                                                            Liver

                                                                                                                 St








               Trematodes (flukes)
                orgaNism             Disease                     traNsmissioN                treatmeNt
                Schistosoma          Liver and spleen enlargement   Snails are intermediate host;   Praziquantel
                A                     (S mansoni, egg with        cercariae penetrate skin of
                                       lateral spine  A ), fibrosis,   humans in contact with
                                      inflammation, portal        contaminated fresh water (eg,
                                      hypertension                swimming or bathing)
                                     Chronic infection with
                B                     S haematobium (egg with
                                      terminal spine  B ) can lead
                                      to squamous cell carcinoma
                                      of the bladder (painless
                                      hematuria) and pulmonary
                                      hypertension
                Clonorchis sinensis  Biliary tract inflammation   Undercooked fish          Praziquantel
                                      Ž pigmented gallstones
                                     Associated with
                                      cholangiocarcinoma




















          FAS1_2019_03-Microbiology.indd   160                                                                         11/14/19   12:21 PM
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