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Inactive 24,25-(OH)2- cholecaciferol ? Calcitriol Stimulates Inhibits No stimulation No inhibition Secretion, absorption
Decreased Ca 2+ absorption Calcium and Phosphate Metabolism II
Serum Ca 2+ (ionized) rises above normal Ca 2+ PTH Bone Ca 2+ Serum Ca 2+ (ionized) returns to normal
Storage of Ca 2+
5
Calcitonin 6 Ca 2+ Increased Ca 2+ excretion (Decreased PO 4 – excretion) Plate 11.14
Thyroid gland (C cells) * 1mmol Ca 2+ = 2mEq Ca 2+ = 40mg Ca 2+
Calcitriol
D. Hormonal regulation of the blood Ca 2+ concentration
Kidney 2 Ca 2+ Gut 4 absorption
1.25 mmol/L* Dietary Ca 2+ Demineral- Ca 2+ Increased
Serum Ca 2+ (ionized) falls below normal Ca 2+ PTH 1 Bone ization Ca 2+ Serum Ca 2+ (ionized) returns to normal
Parathyroid glands (epithelial bodies) Calcitonin 3 Kidney Ca 2+ Decreased Ca 2+ excretion (Increased PO 4 – excretion) 293
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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