Page 318 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003
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A.  Hormone synthesis in placenta, mother and fetus: fetoplacental unit
        1  Early pregnancy:
            Proteohormone synthesis in placenta  2  Later pregnancy:   and Birth
                                           Steroid hormone synthesis in placenta
             Mother          Child
                                           Mother         Child
                                         Adrenal cortex  Adrenal cortex
            Placenta
                                                        Fetal          of Pregnancy
                                                        zone
                                                                       Control
                                                Cholesterol,
                                                pregnenolone
                     hCG                       DHEA   DHEA             Hormonal
                 (human chorionic             DHEA-S  DHEA-S
                  gonadotropin)

         Corpus luteum
         of maternal        Fetal adrenal                              Plate 11.19
         ovary               cortex (FAC)
                                        E                     E

                                                   P
          E      P         DHEA
                           DHEA-S
                Steroid hormones:
                P = progesterone; DHEA(-S) = dehydroepiandrosterone (sulfate); E = estrogens
         B.  Hormone concentrations in plasma during pregnancy


                             hCG
                                                  Estrogens (E)



           Corpus luteum activity  Concentration in maternal plasma  Progesterone (P)  CRH  hPL







            Week     4   8    12  16   20   24  28   32   36   40
          Trimester    1             2             3                  305

       Despopoulos, Color Atlas of Physiology © 2003 Thieme
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