Page 320 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. Control and transport of androgenic hormones; effects of testosterone
on the testes
Hypothalamus ABP = Androgen-binding protein
T = Testosterone
E 2 =Estradiol
SHBG = Sex hormone-binding
CRH GnRH globulin
Adrenal cortex
Seminiferous
tubule
ACTH Androgens and Testicular Function
Anterior LH FSH 3 Activin
lobe of 1
pituitary Leydig Inhibin Sertoli
cells 2 cell
Lumen
ABP
E 2 T T T ABP Plate 11.20
Androgens,
17-ketosteroids SHBG
(DHEA, etc.) Spermatogenesis
E 2 T
Blood Sperma-
Spermatogonia tozoa
B. Genetic sex determination C. Effect of androgens on sexual
Oocytes Primary Spermatocytes differentiation
X X X Y X X Genetic X Y
sex
Female Male
Oogenesis Spermato-
genesis
Ovary Gonadal Testis
X X Each with half set X Y sex
of chromosomes
Sperm
Ova (spermatids)
Fertilization Androgens

X + X X + Y Female secondary Somatic Male secondary
sex differentiation sex sex differentiation
Genetic sex is female Genetic sex is male
Androgens

X X X Y
Somatic cells Female Psychological Male
sex
307
Androgen-related disorders
X,Y = sex chromosomes of female sex differentiation
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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