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180     PART 2: General Management of the Patient


                 PLACEMENT OF CENTRAL VENOUS CATHETERS                 a steep angle toward the underlying visceral pleura of the lung while
                                                                       attempting to locate the posterior border of the clavicle. Once the needle
                 The clinical presentation often dictates the type of catheter to be inserted.   is “walked down” the bone and is positioned underneath the clavicle, it
                 For example, a patient with a hemodynamically significant gastrointes-  is then redirected toward the sternal notch and advanced slowly while
                 tinal hemorrhage may only require a single lumen, large bore CVC for   applying backpressure to the syringe (Fig. 27-1).
                 volume resuscitation in addition to a peripheral IV, whereas a neutropenic
                 patient with septic shock may require a triple lumen CVC in order to
                 simultaneously administer vasoactive drugs and antibiotics. Importantly,   CENTRAL INTERNAL JUGULAR APPROACH
                 most evidence suggests that the number of catheter lumens does not affect   If the patient’s anatomy (scar from previous vascular access) or coagula-
                 the rate of CVC infectious complications.  Once the type of catheter has   tion disorder prevents the use of the subclavian vein, then the internal
                                              2,3
                 been selected, an anatomic site for insertion needs to be determined. The   jugular vein should be utilized for placement of a CVC. The central
                 optimal anatomical location for insertion of CVCs has been a matter of   approach to placing an internal jugular catheter uses the triangle formed
                 debate for many years. In 2001, Merrer and colleagues published a study of   by the two heads of the sternocleidomastoid muscle and the medial por-
                 289 patients who were randomized to have their CVCs inserted in either   tion of the clavicle as the anatomic landmark. Most commonly (though
                 the femoral or subclavian vein.  Patients with femoral vein catheters had   not always), the internal jugular vein is lateral to the carotid artery and
                                       4
                 a dramatically higher incidence of infectious complications (19.8% vs    both vessels run through the triangle beneath the sternocleidomastoid
                 4.5%; p < 0.001) as well as thrombotic complications (21.5% vs 1.9%;     muscle. After the patient has been sterilely prepped/draped and local
                 p < 0.001) as compared to patients with subclavian catheters. The overall   anesthesia has been administered, the patient is placed in Trendelenburg
                 sum  of  mechanical  complications  (arterial  puncture,  pneumothorax,   position and the head is rotated slightly toward the contralateral side
                 hematoma or bleeding, air embolism) was similar between the two groups.   such that the carotid artery can be palpated in the apex of the triangle.
                 To date, there are no randomized trials comparing subclavian versus   The nondominant hand is used to lightly palpate the carotid artery with
                 internal jugular catheters with regard to infectious complications, though   careful attention not to place too much pressure on the skin as this can
                 observational studies suggest a lower rate of infectious com plications with   alter the position of the internal jugular vein. A smaller (eg, 21-gauge)
                 subclavian catheters and a similar rate of mechanical complications.     “finder needle” is often used to locate the vessel prior to using the
                                                                    5,6
                 A recent Cochrane review on comparison of central venous access sites in   introducer needle (18-gauge). This “finder needle” should enter the skin
                 2007 did suggest that subclavian catheters had lower rates of colonization   at the apex of the triangle and be advanced at an angle of 60° above the
                 (defined as culture tip with >103 colony-forming units) and major infec-  plane of the skin. If the nondominant hand is able to delineate the course
                 tious complications (ie, clinical sepsis with or without bacteremia) when   of the common carotid artery, then the needle should be advanced along
                 compared to the femoral site.  As a result of these and other  studies, the   a similar line just lateral to the carotid artery as both vessels are contained
                                      7
                                                            8
                 CDC recommends that, if not contraindicated, the subclavian vein should   within the carotid sheath. If the carotid artery cannot be palpated with the
                 be used for the insertion of nontunneled CVCs in adult patients in an effort   nondominant hand, then the needle should enter the skin at the apex of
                 to minimize infection risk.                           the triangle at a 60° angle to the skin and be advanced in the direction
                                                                       of the ipsilateral nipple. If the needle is inserted to a depth of 3 cm
                                                                       without achieving good blood return, then the needle should be pulled
                 INFRACLAVICULAR SUBCLAVIAN APPROACH                   back  slowly  while  applying  constant  backpressure  to  the  plunger  of
                 Prior  to  the  insertion  of  an  infraclavicular  subclavian  CVC,  a  small   the syringe and redirected more medially before slowly advancing the
                 rolled up towel should be placed between the shoulder blades to move   needle again. After the vessel has been cannulated the modified-Seldinger
                 the vascular structures more anterior. After the subclavian area has been    technique is utilized to complete insertion of the CVC (Fig. 27-2).
                 sterilely prepped and draped (see below) and local anesthesia
                 has been administered, the patient should be placed in Trendelenburg   POSTERIOR INTERNAL JUGULAR APPROACH
                 position. The arm should be positioned at the patient’s side so that the
                 shoulder, clavicle, and sternal notch are aligned and perpendicular to    The posterior internal jugular approach is an alternative to the central inter-
                 the sternum. The subclavian vein arises from the axillary vein and      nal jugular approach that may be used if there is concern that the patient
                 travels beneath to the clavicle and inferior to the subclavian artery prior   would not be able to tolerate a procedure-related pneumothorax (high posi-
                 to  joining  the  internal  jugular  vein  and  forming  the  brachiocephalic   tive end-expiratory pressure and/or high Fi O 2  requirements). The puncture
                 vein. Thus, the clavicle provides a good anatomic landmark for the   site is posterolateral to the sternocleidomastoid muscle, immediately cepha-
                 insertion of  a  subclavian  CVC. The skin should  be  entered  with  an   lad to where the sternocleidomastoid is crossed by the external jugular vein.
                 18-gauge introducer needle 1 to 2.5 cm below the inferior edge of the     The needle should be directed beneath the muscle and advanced in an
                 clavicle and 2 to 4 cm lateral to the midpoint of the clavicle. Once    anterior and inferior direction toward the sternal notch. If blood return is
                 the needle is directly underneath the clavicle, it should be advanced   not obtained, the needle should be pulled back and redirected slightly more
                 toward the sternal notch making sure that the needle remains in the   posterior until venous blood is obtained. Because unintentional carotid
                 plane immediately below  the clavicle. If  no blood return is  obtained,   artery puncture is more likely with this approach, a “finder” needle should
                 then the needle should be pulled back and directed more cephalad. Slight   be used prior to cannulation with a large bore needle.
                 backpressure should be placed on the plunger of the syringe any time the
                 needle is advanced or withdrawn so that blood return can be visualized   ULTRASOUND-GUIDED PLACEMENT
                 when the vessel is cannulated. After the vessel has been accessed, the
                 modified-Seldinger technique is utilized to complete insertion of the CVC.   Ultrasound guidance to assist in the placement of CVCs is a strategy with
                 Inexperienced operators often have difficulty knowing when the needle   growing interest. Early studies did not suggest that ultrasound guidance
                 is directly underneath the clavicle and are appropriately fearful of punc-  for placement of CVCs improved outcomes. For example, Mansfield and
                 turing the visceral pleura. Thus, we often utilize a slightly different   colleagues reported that ultrasound guidance did not impact the rate of
                 approach when supervising an inexperienced operator. Once the skin is   complications or failures in 821 patients randomized to standard inser-
                 entered, the operator is instructed to find the clavicle with the tip of the   tion procedures with anatomic landmark guidance versus ultrasound
                 introducer needle. After the edge of the clavicle is reached, and more   guidance for subclavian vein catheterization.  It is noteworthy that this
                                                                                                       42
                 local anesthesia is given in the area, the introducer needle is retracted   study used ultrasonography to locate the subclavian vein, but did not use
                 slightly (1 cm) and redirected in a more posterior direction by pushing   real-time ultrasound guidance for the actual venipuncture. In contrast,
                 down on the syringe and needle as a unit with the nondominant hand.   several more recent studies have compared the use of real-time ultra-
                 This prevents the inexperienced operator from advancing the needle at   sound with the use anatomic landmarks during the insertion of both







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