Page 165 - Critical Care Notes
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          ■ Maintain glycemic control. Administer IV insulin cautiously to prevent
            hypoglycemia. Target serum glucose levels >60 and <140–180 mg/dL.
          ■ Provide either continuous ECG monitoring or Holter monitoring to detect
            bradycardia →↓ cardiac output and ↓ CPP and arrhythmias especially atrial
            fibrillation.
          ■ Treat and control fever. Administer antibiotics for pneumonia and UTIs.
            Prophylactic antibiotics not recommended.
          ■ Avoid use of Foley catheter if possible. Monitor intake and output closely.
          ■ Institute seizure precautions, and administer anticonvulsants if necessary.
          ■ Provide enteral or PEG tube feedings, following aspiration precautions.
            Elevate HOB 30°. Consider swallowing assessment.
          Endovascular Interventions
          ■ Intra-arterial fibrinolysis
          ■ A combination of IV and intra-arterial fibrinolysis
          ■ Mechanical thrombectomy to remove offending thrombus with select
            thrombus retrievers
          ■ Extra-intracranial bypass (EC-IC) not recommended; no benefit shown over
            medical therapy
          ■ Use of intracranial angioplasty and/or stenting not well established
                      Herniation of the Brain
          A brain herniation occurs when brain tissue, CSF, and blood vessels are moved
          away from their usual position inside the skull. May result from brain swelling
          caused by a head injury, stroke, or brain tumor. Other causes include abscess,
          hemorrhage, hydrocephalus, and swelling after radiation therapy.
           Brain herniation can cause a massive stroke and can quickly lead to brain
          death or death.
           Signs and symptoms:
          ■ Cardiac arrest
          ■ Cushing’s triad of impending herniation: an increase in pulse pressure;
            bradycardia; and slow, irregular respiratory rate
          ■ Headache
          ■ Lethargy, difficulty concentrating, drowsy or agitated → stupor and coma
          ■ Loss of brainstem reflexes such as blinking, gagging
          ■ Changes in pupillary reaction, sluggish → fixed and dilated pupils
          ■ Hemiparesis → decortication, decerebration, flaccidity
          ■ Increased BP, irregular and slow HR
          ■ Increased BP, hyperventilation → irregular breathing → Cheyne-Stokes →
            respiratory arrest


                                   NEURO
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