Page 244 - Critical Care Notes
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           MULTISYS
          ■ Hemorrhage or shock
          ■ Surgical complications
          ■ Acute pancreatitis
          ■ Burns, extensive tissue damage, and/or necrotic tissue
          ■ Aspiration
          ■ Multiple blood transfusions
          ■ Inadequate fluid resuscitation
           Signs, symptoms, and management are similar to those for sepsis, severe
          sepsis, and septic shock. Initial organ failure includes the cardiovascular, pul-
          monary and renal systems and can progress rapidly to the neurological, hema-
          tological, hepatic, metabolic, and GI systems.
          ■ Monitor for decreasing SBP, MAP, O 2 saturation, urine output, platelets,
            bilirubin, alkaline phosphatase, aspartate aminotransferase, alanine amino-
            transferase, serum lactate, and a Glasgow Coma Scale <15 with changes in
            mental status.
          ■ Monitor for increasing respiratory rate, coagulation times, and creatinine
            level.
          ■ There is also an increased risk for DIC.
          ■ The need for dialysis is an early warning sign of MODS.
          ■ The Sequential Organ Failure Assessment score (SOFA score) can be
            calculated online at http://www.mdcalc.com/sequential-organ-failure-
            assessment-sofa-score/
                             Trauma
                           Pathophysiology
          ■ Blunt trauma: Resulting from motor vehicle crashes (MVCs), falls, blows,
            explosions, contact sports, and blunt force injuries (e.g., from a baseball bat).
            ■ Estimating the amount of force a person sustains in an MVC = person’s
             weight × miles per hour of speed.
            ■ During an MVC, the body stops but the tissues and organs continue to
             move forward and then backward (acceleration-deceleration force).
          ■ Penetrating trauma: Resulting from gunshot wounds, stabbings, and
            firearms or implement (missile, shrapnel) injuries.
            ■ There is direct damage to internal structures, with damage occurring
             along the path of penetration.
            ■ Penetrating trauma usually requires surgery.
          ■ Traumatic brain injury (TBI): Resulting from a skull fracture, concussion,
            contusion, cerebral hematoma, and diffuse axonal injury.

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