Page 35 - Clinical Application of Mechanical Ventilation
P. 35

Chapter 1















                        Principles of Mechanical Ventilation



                        David W. Chang


                        Outline



                                             Introduction                         Ventilatory Failure
                                             Airway Resistance                      Hypoventilation
                                               Factors Affecting Airway Resistance  Ventilation/Perfusion (V/Q)
                                               Airway Resistance and the Work         Mismatch
                                                 of Breathing (DP)                  Intrapulmonary Shunting
                                               Effects on Ventilation               Diffusion Defect
                                                 and Oxygenation                  Oxygenation Failure
                                               Airflow Resistance                   Hypoxemia and Hypoxia
                                             Lung Compliance                      Clinical Conditions Leading
                                               Compliance Measurement               to Mechanical Ventilation
                                               Static and Dynamic Compliance        Depressed Respiratory Drive
                                               Compliance and the Work              Excessive Ventilatory Workload
                                                 of Breathing                       Failure of Ventilatory Pump
                                               Effects on Ventilation             Summary
                                                 and Oxygenation                  Self-Assessment Questions
                                             Deadspace Ventilation                Answers to Self-Assessment Questions
                                               Anatomic Deadspace                 References
                                               Alveolar Deadspace                 Additional Resources
                                               Physiologic Deadspace


                        Key Terms



                                             airway resistance                    anatomic deadspace
                                             alveolar deadspace                   deadspace ventilation
                                             alveolar volume                      diffusion defect


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