Page 671 - Clinical Application of Mechanical Ventilation
P. 671

Case	Studies  637


                                             Patient Management


                                             Initially, the patient’s respiratory status was stable but it began to deteriorate on
                                             the second day. The ventilator settings were changed to accommodate the patient’s
                                             needs. The ventilator settings were: CMV mode, f 35/min, V  720 mL, F O  100%,
                                                                                                             2
                                                                                                T
                                                                                                           I
                                             20 cm H O PEEP. The peak inspiratory pressure was 80 cm H O, and the plateau
                                                     2
                                                                                                   2
                                             pressure was 70 cm H O. The blood gas results were:
                                                                2
                                                   pH           7.27
                                                   PaCO 2       43 mm Hg
                                                   PaO 2        72 mm Hg
                                                        -
                                                   HCO          19 mEq/L
                                                        3
                                                   SpO 2        92%
                                                   Mode         CMV
                                                   f            35/min
                                                   V T          720 mL
                                                   F O 2        100%
                                                    I
                                                   PEEP         20 cm H O
                                                                        2
                                                   PIP          80 cm H O
                                                                        2
                                                   P PLAT       70 cm H O
                                                                        2
                                               Because of the increasing pressure requirement, pressure-controlled ventilation
                            In PCV, the initial pres-  (PCV) was started to minimize the occurrence of volume- or pressure-induced lung
                          sure may be set at 10 cm H 2 O
                          below the peak inspiratory   injuries. The pressure on PCV was initially set at 70 cm H O (10 cm H O below
                                                                                                2
                                                                                                           2
                          pressure on CMV.   the peak inspiratory pressure on CMV). Other ventilator parameters for PCV were:
                                             inspiratory time 1 sec, f 35/min, F O  100%, 20 cm H O PEEP. The blood gases on
                                                                                           2
                                                                            2
                                                                          I
                                             these settings were as follows:
                                                    pH          7.31
                                                    PaCO 2      41 mm Hg
                                                    PaO 2       56 mm Hg
                                                          -
                                                    HCO         20 mEq/L
                                                         3
                                                    SpO 2       88%
                                                    Mode        PCV
                                                    PIP         70 cm H O
                                                                        2
                                                    f           35/min
                                                    F O 2       100%
                                                     I
                                                    PEEP        20 cm H O
                                                                        2
                                               The inspiratory time was then increased to 2 sec to keep the PaO  in the 70s. The
                                                                                                      2
                            In PCV, the minute vol-  I:E ratio was changed to 4:1 to provide longer inspiratory time. Subsequently, the
                          ume is primarily determined
                          by the pressure, inspiratory   minute volume was increased with these settings and the pressure was lowered to
                          time, and lung compliance.  50 cm H O. Blood gases on these settings were satisfactory. The minute volume of
                                                     2
                                             the patient was trended carefully during the use of PCV.
                                               The patient was placed on a Roto-bed and was administered neuromuscular and
                            In ARDS, a lung protec-  sedative agents to minimize agitation and oxygen consumption. For proper airway
                          tion strategy includes use of
                          low pressure and volume.  management, a tracheostomy was performed because extended mechanical ventila-
                                             tion was anticipated.




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