Page 570 - Cardiac Nursing
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                  546    PA R T  I V / Pathophysiology and Management of Heart Disease
                  chest pain and hypotension, and is most commonly seen in the  undergoing PCI is 0.8% to 5.5%, and has decreased significantly
                  catheterization laboratory. Treatment includes nitroglycerin or a  from earlier experiences. Decreased incidence of complications
                  low-pressure balloon. If spasm is significant, the patient may be  has been seen with the decrease in sheath size and the current
                  maintained on nitroglycerin and intravenous fluids overnight.  standard drug regimen for stent management.
                                                                        Hematoma formation or ecchymosis is frequent and self-limiting.
                  Arrhythmias and Conduction                          It usually requires no intervention other than comfort measures.
                  Disturbances                                          Retroperitoneal bleeding caused by large hematomas dissecting
                                                                      into the retroperitoneum are life threatening and need prompt at-
                  Ischemia during treatment can cause ECG changes, including  tention by the nursing and medical staff. Inadvertent puncture of
                  transient heart block, atrial arrhythmias, or ventricular arrhyth-  the artery proximal to the inguinal ligament (i.e., the external il-
                  mias. Significant arrhythmias occur in approximately 1% of PCI,  iac artery) while placing the arterial sheath is frequently the cause.
                  usually as a result of prolonged ischemia during balloon inflation  There is less supporting tissue in this area, and it is more difficult
                  or luminal occlusion with devices. 57               to compress the puncture site. Retroperitoneal bleeding is charac-
                                                                      terized by lumbar or groin pain, a significant drop in hematocrit,
                                                                      hypotension, and possible bradycardia or tachycardia. Diagnosis is
                  Contrast Medium-Related                             confirmed by a computed tomography scan. Treatment involves
                  Complications                                       transfusion and fluid resuscitation to maintain adequate blood
                                                                      pressure, reversal of anticoagulation and occasionally surgical re-
                  Hypersensitivity reactions to radiocontrast medium are independ-
                  ent of amount or rate of infusion. This reaction can occur imme-  pair of the artery.
                  diately (within 1 hour) or delayed (from 1 hour to 1 week). Signs  Arterial thrombosis at the puncture site may lead to occlusion
                  and symptoms include pruritus, urticaria, angioedema, laryn-  of the artery or distal thrombosis into the extremity. Preexisting
                  gospasm, bronchospasm, hypotension with loss of consciousness,  peripheral vascular disease increases the risk of a thromboembolic
                  and rarely hypovolemic shock and death. Risks of hypersensitivity  event. Surveillance of distal circulation and sensory checks should
                  reactions are previous anaphylactoid reaction to contrast, asthma,  be continued after sheath removal. Signs of loss of pulse, color
                  a history of allergic rhinitis, or drug or food allergies. Strategies to  changes, decreased sensation, decreased temperature, or decreased
                  prevent recurrent reactions include use of low osmolar contrast  motor function are potential indicators of thrombosis.
                  and a prednisone regimen (premedicate with prednisone 13 hours  Pseudoaneurysm is an extra-luminal cavity in communication
                  before the procedure, administer a second dose at 7 hours before the  with an adjacent artery, usually the femoral artery. Inadvertent
                  procedure, and administer a third dose 1 hour before the proce-  puncture of the superficial femoral or profunda femoris artery in-
                  dure), an H1 antihistamine (diphenhydramine) 1 hour before the  creases the incidence of arterial complications. Contributing fac-
                  procedure, and possibly an H2 blocker (cimetidine or ranitidine),  tors include inadequate compression of the puncture site, heparin
                  which has shown conflicting benefit prior to the procedure. For  use, intramural arterial calcifications, and hypertension. On phys-
                  emergency procedures, an intravenous steroid (hydrocortisone)  ical examination, the patient may have a pulsatile mass, systolic
                  should be given immediately and every 4 hours until completion of  bruit, normal distal arterial pulses, and pain in the groin. Doppler
                  procedure and diphenhydramine 1 hour before the procedure. 38  ultrasound and color flow imaging are used to confirm the diag-
                     Contrast-induced nephropathy can cause temporary or permanent  nosis and delineate the location and size of the pseudoaneurysm.
                  renal dysfunction. Patients with diabetes or preexisting renal insuffi-  Although most small pseudoaneurysms spontaneously close in 4
                  ciency, and older adults are at highest risk. Limiting volume of con-  to 8 weeks without sequelae, they may enlarge or hemorrhage, es-
                  trast and hydration prior to PCI remains the best preventive strategy.  pecially in patients with prolonged anticoagulation. Treatment in-
                     Volume overload (ECF, water, or both; Chapter 7) can be due  cludes ultrasound-guided compression, thrombin injection with
                                                                                                    61
                  to hypertonic contrast agents, myocardial depression secondary to  ultrasound guidance, or surgical closure.
                  ischemia, poor baseline ventricular function, routine diuretics and  Arteriovenous (AV) fistula is a communication between an artery
                  other medication held prior to PCI, and excessive volume pre-  and vein. The mechanism of injury involves a puncture through
                  loading. Prevention involves continued monitoring of ECF and  both the femoral artery and vein, which results in a false communi-
                  water status before and after the procedure, particularly in patients  cation. On physical examination, the patient may have a pulsatile
                  with LV dysfunction, and reinstituting routine medications. Ad-  mass in the groin and a continuous systolic–diastolic bruit; over
                  ditional diuretics may be needed.                   time, temperature of the extremity decreases due to high flow
                                                                      through the fistula and ischemia of the extremity; a thrill may be
                                                                      present at the site; and heart failure may result if the fistula is per-
                  Cerebrovascular Complications
                                                                      sistent. Doppler ultrasound and color flow imaging confirm diag-
                  Transient ischemic attacks or cerebral vascular accidents secondary  nosis. Surgical treatment may be necessary for closure and repair of
                  to plaque disruption may occur from manipulation of catheters and  the peripheral vasculature.
                  devices during intervention in patients with diffuse atherosclerotic  Septic endarteritis is rare and has been implicated in chronic in-
                  disease. 58  A rare complication is spontaneous intracerebral hemor-  timal damage and stasis due to flow turbulence in the region of a
                  rhage with aggressive anticoagulation and antiplatelet agents.  pseudoaneurysm or AV fistula, multiple procedures through the
                                                                      same access site, obesity, or sheaths left in place for over 24 hours.
                  Groin Complications                                 In high-risk patients, antibiotics are given postprocedure and may
                                                                      be continued postdischarge if warranted. 62
                  Bleeding post-PCI is an independent predictor for short- and  VCD complications include infection, femoral artery compro-
                  long-term clinical events with increased mortality and morbid-  mise, arterial laceration, uncontrolled bleeding, pseudoaneurysm,
                  ity. 59,60  The incidence of vascular complications among patients  AV fistula, as well as device embolism and limb ischemia. These
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