Page 121 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Chronic Renal Failure
Compensated
renal failure
Normal kidney GFR
GFR 700 RPF Creatinine
Plasma concentration (%) 500 V . Urea
RPF

.
V Failure I
300
2–
HPO 4 , Mg
Uric acids 2+ Renal
+
100 Na , K +
2+
Ca
100 50 0 Chronic
Glomeruar filtration rate (% of normal rate)
Plate 5.10
Decompensated renal failure
Anemia Erythropoietin
Renin
Ischemia
PGE 2
GFR

Hypertension

Retention of:
VnO 4 Break-down of
Abnormalities NaCl free fatty acids
of H 2 O NH 3 production
electrolyte ‘middle
balance molecules’ Calcitriol
uremia toxins
uric acids
urea Hyperlipidemia
H + Acidosis
K +
Pruritus, Phosphate
arthritis,
gout Plasma-Ca 2+
Demineralization
Neuropathy, gastroenteropathy,
susceptibility to infection, coagulopathies 111

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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