Page 123 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Disorders of Salt and Water Balance in Renal Failure

                 Renal failure                             Ischemia
                                         Intracellular volume
                                   H 2 O

                                             Cerebral
                 Cell swelling   •           edema
                               VUrine
                                                              Renin
        +   –                      H 2 O  Extracellular volume         Failure II
          3   K +    1     VnO 4   NaCl
              Cl –          ?                                 Angio-
           4                                                  tensin
              Na +                             Peripheral edema,       Chronic Renal
                          Ouabain              pulmonary edema
              Ca 2+               ?
                     2
                            ANF     Hypervolemia
                                                                       Plate 5.11
                                    Vasoconstriction      Hypertension
            Cell metabolism
            hormone release,
            nervous system
        B.  Effects of Renal Failure on Mineral Balance
          Renal failure
                                              Calcitriol

                                2–
                             HPO 4
                                                    Gut
                              Ca 2+


                                            Calcium phosphate

                   Calcium
                   phosphate
                             Para-
                             thyroid
                                               Joint pains  Pruritus
                                    Abnormalities

                                PTH
                                                                      113
                                     Stomach Nervous system Blood cells Gonads

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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