Page 119 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Acute Renal Failure
                                        Reduced
                                        renal perfusion,
                    Glomerular inflammation,  especially in shock
             1      poisoning, etc.
                                                           2+
                                                         [Ca ]
                                                        intracellular
                    Fibrin deposition  Vasoconstriction
                             GFR
                                             Renin
                                                Angiotensin            Failure
                 Leak        Adenosine
                                                                       Renal


                      Obstruction of                                   Acute
                      tubular lumen
                                                                       Plate 5.9
                                                      Obstruction
                               Sludge

             Hypothetic
             mechanism        Ischemia
             (see text)
        2
         Acute phase
                 GFR            3
       Re-                       Secondary phase
       absorption                                      4
                                      GFR               Recovery
                             Re-
                             absorption
                                                    Reabsorption and GFR
                                                        normalized


           Urine volume
        100
        %                 Oliguria
         0
        100        GFR
        %                                    Polyuria
         0
           2     14  Days  26
                        Hyperhydration,
                        hyperkalemia,       Dehydration,
                        ascending           hypokalemia
                        pyelonephritis                                109

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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