Page 127 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
P. 127

A.  Normal Pregnancy
              Prostaglandins (esp. E 2 )

                                   Vasodilation
           Placenta
                                                                       in Pregnancy

                                                   Vasoconstriction
                                      R
                     Blood pressure
                                                         Renin
                                      RPF
                                                          Angiotensin  Disease
                      Uric acid,
                   Na + glucose  GFR       Na +  Na +
                                                          Aldosterone  Kidney
         Blood volume
                                                                       Plate 5.13

                                         Na +
                                                  +
                                                 Na  and H 2 O
                                                  retention
        B.  Nephropathy of Pregnancy
                                  2
                   Prostaglandins (esp. E 2 )
                      Thrombokinase
            Placenta   1
                        Blood clotting
                                       Vasoconstriction
                         Fibrin                         Ischemia,
                                                        CNS
                                             3
                                 H 2 O
                                             R
                               Abnormal
                               permselectivity
         Edema                           RPF            Hypertension
                    Na +  Uric acid             +
                                           Na +  Na
                                                         Renin
                                                           Angiotensin
          Blood volume
                                   GFR
                          Proteins                         Aldosterone

                                                   +
                                                  Na and H 2 O
                         Proteinuria               retention          117
       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
   122   123   124   125   126   127   128   129   130   131   132