Page 131 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
P. 131

A.  Urolithiasis
                                PTH
                                     Calcitriol
              Mobilization         2
                                                     Absorption



                                                  Disordered
                                                  metabolism
                                     2–  2+
                                  HPO 4  Ca
                      PTH                            3                 Urolithiasis
                                           Oxalate       Xanthine
           Reduced
           reabsorption                          Uric acid
                   2–
                 HPO 4
                                         Ca 2+                         Plate 5.15
             Cystin                                 Hypovolemia
                                                   4       Stress
           Ca 2+
                                      H +
                                                   ADH

                                          H 2 O   Urine concentration


              1                                Calcium  CaHPO 4
                  Cystine  Xanthine  Uric acid  NH 3  oxalate  MgNH 4 PO 4
                                                 Citrate etc.
                                            pH

         5                                Metastable solution
            Renal damage                   Stagnant
                                             urine

                                     Precipitation        pH
                                     Stone formation
                   Colics
                                         Infection

                                           Kidney stones
                                                                      121

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
   126   127   128   129   130   131   132   133   134   135   136