Page 167 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Causes and Consequences of Constipation and (Pseudo-)Obstruction

Psychogenic Surgery, Mechanical obstruction:
reflex disorder trauma, luminal, mural, external
e.g. anism peritonitis, etc. (foreigm body, tumor, hernia,
Rectal adhesion, stricture, etc.)
distension
Acute reflex Neurogenic or myogenic (Pseudo-)Obstruction
disorder of transport
Contraction
(instead of dilation)
of the pelvic Paralytic ileus
floor

Paralysis Abnormal Constipation and
Food low in bulk dilatation
see photo below
Intestinal volume Drugs
(opiates, pheno-
thiadiazines, etc.)
Intestinal motility Constipation Plate 6.12

Obstruction Pseudo-obstruction
Far towards anus

Ascension of bacteria Distension
Ischemia
Endotoxins
Inflammation
VIP, prostaglandins
Wall edema
Spasm
Absorption , secretion

Megacolon
(here: Hirschsprung’s disease)
Vomiting Hypovolemia Pain 157
Photo: Sleisenger, Fortran. Gastrointestinal Disease. 5th ed. Philadelphia: WBSaunders; 1993; Vol.1: 892
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
All rights reserved. Usage subject to terms and conditions of license.