Page 225 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Causes and Consequences of Pulmonary Hypertension

               Altitude  Embolism   Lung disease and other  Mitral valve disease
                                    ventilatory disorders  Left heart failure
                   Capillary                                   Left
                   network                                     atrium
                   Alveolus
                                                    Left
                                                    ventricle          Hypertension

                                       Numbers of vessels
           Hypoxic                           or their cross-  Filling or ejection
           vasoconstriction  Vascular obstruction       sectional area  3
                                                      Mitral opening (cm 2 )
           Hematokrit  Hypoxia                         2               Pulmonary

        Blood viscosity                                1
          Physical activity,                           0               Plate 7.21
          fever,                                         10  30 mmHg
          left-to-right shunt                           Left atrial pressure

             Cardiac  x  Pulmonary vascular  +  Left atrial  =  Mean pulmonary a.
             output     resistance       pressure    pressure
                                                          _
             (CO)       (PVR)            (P LA )         (P AP )
                         chronic    Pulmonary hypertension  acute


                                     Cyanosis        Increased
                       Right heart:  Congestion of  central venous
                       increased load  neck veins     pressure
                                Dyspnea
                                Liver
                       Hypertrophy  congestion


                         Dilation
                                                           (after Netter)
                                  Edema
          S
               S           Heart failure
            I    V 6
                                                          Right heart
                                                          failure
                                                             Shock    215

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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