Page 305 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Histamine and Bradykinin
Drugs Burns,
Antigens inflammation Factor Xlla, plasmin, trypsin, pepsin, toxin
Immunoglobulin E
Complement Kallikreinogen Kallikrein
Tumor
Epinephrine Kallidin Kinin Kininogen
cAMP
Mast cell
PGE 2 Bradykinin, Serotonin
1 2
Histamine Bradykinin
Secretion
Stimulation of peri-
HCl secretion pheral nerve endings
Diuresis Histamine,
Contraction Puritis Pain Vascular permeability
of muscles
of: Vasodilation
Cardiac
uterus contractility Oncotic pressure
bronchi Tachycardia Plate 9.20
gut
Edema
Airway Catecholamine
resistance release Hypovolemia
Abdominal cramps
Drop in
Bronchospasm blood pressure
B. Serotonin
Tumors in the entero- Vascular damage
chromaffin intestinal cells

Thrombocytes
Liver metastases
Serotonin
Thrombocyte
aggregation

Contraction of muscles Vascular
of: ?
small permeability
intestine uterus bronchi vessels

Intestinal motility
Broncho- Migraine
spasm Blood Endocardial
fibrosis
Diarrhea Blood pressure coagulation Edema 295
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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