Page 307 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Eicosanoids
Glucocorticoids
Bradykinin, Histamine Epinephrine (β) Acetylsalicylic acid etc.
epinephrine, Serotonin Ca 2+
etc.
Bartter’s syndrome
Transport
1
Phospholipase A 2 defect
Arachidonic acid
Phospholipids
Lip- Cyclo-
oxygenase oxygenase

? Eicosanoids
Inflammation 3
Cell swelling
Tissue lesions
Prostaglandin G
2 Plate 9.21
Leukotrienes TXA 2 PGF 2α PGE 2 PGI 2

Lipolysis
Hormone
Chemotaxis, release
adhesion
Thrombus
formation
Release of:
histamine,
insulin,
lysosomal
enzymes
Contraction of
smooth muscles Vessels Bronchi Gut Uterus
Persistent
ductus arteriosus Asthma Abortion
Blood Vomiting,
Vascular pressure diarrhea
permeability
HCl/pepsin
secretion
Edema
GFR
Fever
Osteolysis Diuresis Renin Pain Ulcers
Natriuresis 297

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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