Page 319 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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D.  Electromyography
                        α-motor neuron
                        Muscle fiber

                       1

                                                                       II
                       Electrode

                                                     Death of individual  and Muscles
         Death of individual                           motoneurons
          muscle fibers                         1 mV
                                                                       Motor Unit
                                    normal
          2

                                  Reinnervation
                                                                       Plate 10.6
                                          3

                              500 µV                            5 mV

                 Myogenic myopathy               Neurogenic myopathy
        E.  Creatine Metabolism

                                          1               Creatine
                          H 2 C  COO –                    in plasma
        Liver                                             Creatinine
             Creatine      N   NH 2     Concentration     in urine
                        H 3 C  C                          Creatine
                               +                          kinase
                             NH 2                         in plasma
                                       0
                                                              Time
                                                      Death of
                                     Creatine         muscle cells
                                     phosphate
                                Creatine          Muscle
                                kinase            dystrophy
               C  O
           CH 2
                           Creatine
           N   NH
        CH 3  C
                     Creatinine
             NH +
                                                     Normal excretion:
                    Muscle                           Creatine     0
                                                     Creatinine  1.8 g/day
                                       Kidney                         309
       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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