Page 371 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Effects of Abnormal Cerebral Perfusion
1 Paralysis
Bleeding Irreversible
Ischemia Dys- damage
K 10–20s
O 2 + function
3–5min
4–6s
ATP
Cell death Disorders
Onset of anoxia
Depolarization Na + Ca 2+
Cl – Glutamate Thromboxan
Vasoconstriction
H 2 O Necrosis
Nerve cell Brain tissue Cerebral Blood Flow:
Lesion of cells
at margin of
Inflammation ischemic region
Cell swelling Intracranial
pressure
B. Vascular Occlusion as Cause of Ischemia
Hemiparesis, Plate 10.32
hemianesthesia,
apraxia,
apathy
Hemianesthesia,
Anterior hemiparesis,
cerebral a. conjugate deviation,
visual field defect,
Internal aphasia, apraxia,
carotis a. Medial hemineglect
cerebral a.
Posterior Basal ganglia Hypokinesia
communi- Anterior Internal capsule Hemiparesis
cating a. choroid a. Optic tract Hemianopsia
Posterior Thalamus Hemianesthesia
cerebral a.
Hemianopsia
Basilar a. Branches III, VII, XII,
Parkinson’s dis., hemiparesis
of basilar a.
Mid-brain V, VI, VII, hypacusis, ataxia,
nystagmus, Horner’s syndrome
Tetraplegia,
pseudobulbar paralysis
Pons
V, X,
nystagmus, Horner’s syndrome,
hemiataxia, hiccough,
hemianästhesia, ageusis,
hypakusis
Medulla XII, 361
oblongata hemiparesis, Hemihypesthesia

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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