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294  n  MIDDLE-RANGE THEORIES



              Approaches are available to examine and   nursing. Since then, meta-analyses have been
           reduce  bias  from  operating  within  a  meta-  conducted and published in a wide variety
   M       analysis. Some ways that biased conclusions   of areas, such as patient outcomes of nurse
           can  occur  in  a  meta-analysis  are  effects  of   practitioners and nurse midwives, job satis-
           a  bias  toward  publishing  positive  but  not   faction and turnover among nurses, relation-
           negative results, giving each study an equal   ship  between  postpartum  depression  and
           weight in the meta-analysis despite the fact   maternal–infant interaction, effects of educa-
           they differ in sample size or quality, inclusion   tional interventions in diabetes care, quality
           of multiple tests of a hypothesis from an indi-  of  life  in  cardiac  patients,  and  nonnutritive
           vidual study, and not ensuring an acceptable   sucking in preterm infants.
           level of agreement or reliability among raters   The  outcome  of  this  quantitative
           in coding the study characteristics.     approach  for  reviewing  the  literature  has
              It can be argued that not all studies syn-  tremendous  potential  for  a  practice-based
           thesized in a meta-analysis should be given   discipline such as nursing. Meta-analysis of
           equal  weight.  Some  studies  may  be  poorly   the abundance of research being conducted
           designed  and  have  small  unrepresentative   can  benefit  nursing  practice.  Not  only  will
           samples, whereas other studies use random-  the use of meta-analysis further knowledge
           ized control group designs with large sample   development in the discipline of nursing, but
           sizes. To remedy this problem, studies can be   it also can help nurses in the clinical setting
           evaluated and assigned a quality score. The   to decide whether to apply research findings
           meta-analysis  can  then  be  calculated  with   to their practice based on the size of the dif-
           studies weighted by their quality scores.  ference an intervention makes. Meta-analysis
              A source of nonindependence in a meta-  can resolve issues in nursing where there are
           analysis  can  result  from  using  multiple   multiple studies with conflicting findings. In
           hypothesis  tests  based  on  multiple  variable   addition,  meta-analysis  highlights  gaps  in
           measurements obtained from a single study   nursing research for future studies.
           (Strube  &  Hartman,  1983).  One  suggested
           remedy  when  selecting  findings  obtained                    Cheryl Tatano Beck
           from  multiple  measures  of  the  hypothesis
           tests located within a single study is to col-
           lapse the various findings into a single, global
           hypothesis test.                             Middle-range theories
              One  assumption  that  should  be  met
           before  specific  studies  are  quantitatively
           combined in one meta-analysis is that each   Middle-range  theories  are  described  by
           study provides sample estimates of the effect   Merton (1968, p. 9) as those that “lie between
           sizes  that  are  representative  of  the  popula-  the  minor  but  necessary  working  hypoth-
           tion  effect  size.  Homogeneity  tests  can  be   eses  that  evolve  in  abundance  during  day-
           calculated to identify any outlier studies. If   to-day  research  and  the  all-inclusive  sys-
           outliers are identified, they can be removed.  tematic  efforts  to  develop  unified  theory.”
              Meta-analysis first appeared in the nurs-  He goes on to say that the principal ideas of
           ing literature in 1982, when O’Flynn published   middle-range theories are relatively simple.
           her  article  describing  meta-analysis  in  the   Simple here means rudimentary, straightfor-
           “Methodology  Corner”  of  Nursing  Research.   ward ideas that stem from the focus of the
           A meta-analysis of the effects of psychoedu-  discipline.  Thus,  middle-range  theory  is  a
           cational interventions on length of postsur-  basic, usable structure of ideas, less abstract
           gical hospital stay (Devine & Cook, 1983) was   than  grand  theory  and  more  abstract  than
           the  first  meta-study  analysis  published  in   empirical  generalizations  or  microrange
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