Page 390 - Encyclopedia of Nursing Research
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OReM’S SeLF-CARe THeORy  n  357



             biased study threatens internal validity if the   by  masking  the  presence  of  an  association
             distortion is sufficient to lead to an errone-  between the independent and the dependent
             ous inference about the relationship between   variables.  A  distinction  between  confound-  O
             the  independent  and  dependent  variable.   ing bias and other types of bias is that con-
             Potential sources of bias that can threaten the   founding may be correctable at the design or
             internal validity of observational studies are   analysis stage of the study, whereas bias due
             those related to selection, measurement, and   to  selection  and  measurement  problems  is
             confounding.                             usually difficult or impossible to correct in the
                 Selection bias is a distortion in the esti-  analysis.  Confounding  can  be  controlled  or
             mate of effect resulting from (a) flaws in the   minimized at the design stage of the study by
             choice of groups to be compared; (b) inability   restricting the study sample or by matching
             to locate or recruit participants selected into   the comparison groups. At the analysis stage,
             the  sample,  resulting  in  differential  selec-  confounding can be controlled or minimized
             tion  effects  on  the  comparison  groups;  and     by using a multivariable approach to the sta-
             (c)  subsequent  attrition  of  participants  who   tistical analysis to adjust for the confounding
             had  initially  agreed  to  participate,  which   factors  or  by  examining  the  independent–
             changes the composition of the comparison   dependent variable relationship within spec-
             groups.                                  ified levels or categories of the confounding
                 Measurement  bias  occurs  when  the   factors  (stratified  analysis).  Confounding
             independent variable or outcome (dependent   variables should not be confused with media-
             variable) is measured in a way that is system-  tor and moderator variables.
             atically  inaccurate  and  results  in  distortion   In  summary,  observational  designs  are
             of the estimate of effect. The major sources   prevalent  in  nursing  research  because  they
             of measurement bias are (a) a defective mea-  are  used  to  describe  phenomena  in  early
             suring instrument, (b) a procedure for ascer-  stages  of  knowledge  development  and  pro-
             taining  the  outcome  that  is  not  sufficiently   vide  a  basis  for  designing  experimental
             sensitive  and  specific,  (c)  the  likelihood  of   interventions. In addition, they are the only
             detecting the outcome dependent on the par-  feasible approach to hypothesis testing when
             ticipant’s status on the independent variable,   it is unethical to manipulate the independent
             (d) selective recall or reporting by study par-  variable.  In  the  absence  of  randomization
             ticipants, and (e) lack of blind measurements   and  manipulation,  myriad  sources  of  bias
             when indicated.                          can  influence  observations  and  conclusions
                 Because of the lack of randomization in   drawn from naturally occurring events; thus,
             a  nonexperimental  study,  uncontrolled  con-  rigorous observational designs and methods
             founding variables are a major threat to inter-  are essential.
             nal validity. Unless confounding factors are
             controlled in the design of the study or in its                 Janet C. Meininger
             analysis,  distortion  in  the  estimate  of  effect
             will  result.  A  confounding  factor  operates
             through  its  association  with  both  the  inde-
             pendent and the dependent variables. It can   Orem’s self-care theOry
             distort the results in either direction; that is,
             it can lead to an overestimation of the rela-
             tionship  between  the  independent  and  the   One of nursing’s grand theories, Orem’s Self-
             dependent  variables  by  producing  an  indi-  Care  Deficit  Nursing  Theory  (SCDNT),  is  a
             rect statistical association, or it can lead to an   vital  component  of  nursing’s  philosophical
             underestimate  of  the  relationship  between   foundation.  The  impetus  of  the  theory,  to
             the independent and the dependent variables   define a curriculum for practical nursing, led
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