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356  n  OBSeRVATIONAL ReSeARCH DeSIGN



           myriad  sources  of  bias  that  can  invalidate   comparative design is referred to as a cohort
           naturally occurring events, rigorous designs   study. Participants are measured or catego-
   O       and methods are required to minimize bias.   rized on the basis of the independent variable
           Observational  designs  should  not  be  con-  and  are  followed  over  time  for  observation
           fused  with  observational  methods  of  data   of the dependent variable. In a cohort study,
           collection.                              it  is  established  at  the  outset  that  subjects
              Observational  designs  are  used  when   have not already exhibited the outcomes of
           there is not enough knowledge about a phe-  interest (dependent variable). Thus, the time
           nomenon  to  manipulate  it  experimentally.   sequencing of events can be established. In
           Sometimes research involving human partic-  other words, it can be demonstrated that the
           ipants is restricted to observational designs   independent  variable  preceded  the  occur-
           because  of  the  nature  of  the  phenomenon;   rence of the dependent variable.
           that  is,  experimental  research  is  precluded   Another  type  of  longitudinal,  compar-
           for ethical reasons.                     ative  design  is  a  case–comparison  study,
              Observational designs include quantita-  sometimes  referred  to  as  a  case–control
           tive, descriptive studies as well as analytical   study. In this design, the flow is the opposite
           studies that are designed to test hypotheses.   of  a  cohort  study.  Participants  are  selected
           Descriptive,  observational  studies  provide   and  categorized  on  the  basis  of  the  depen-
           a basis for further study by describing and   dent  variable  (the  outcome  of  interest).  The
           exploring  relationships  between  variables,   purpose  of  the  study  is  to  test  hypothe-
           informing  the  planning  of  health  services,   ses  about  factors  in  the  past  (independent
           and describing clinical practice for individ-  variables)  that  may  explain  the  outcome.
           ual  clients  or  groups  of  clients.  In  contrast,   Although  case–comparison  designs  are  not
           analytic research is designed to test specific   prevalent in the nursing research literature,
           hypotheses  to  draw  conclusions  about  the   they have great potential for studies of out-
           impact of an independent variable or set of   comes that occur infrequently. Furthermore,
           variables on an outcome, the dependent var-  this design is very efficient because it is pos-
           iable under scrutiny. Observational designs   sible to achieve greater statistical power with
           are  classified  as  longitudinal  or  cross  sec-  a smaller sample size than in other types of
           tional. In a cross-sectional study, all the mea-  observational designs.
           surements relate to one point in time; in the   Longitudinal  comparative  designs  are
           longitudinal approach, measurements relate   also classified according to the time perspec-
           to at least two points in time.          tive of the events under study in relation to
              A  cross-sectional  study,  sometimes   the investigator’s position in time. A study is
           referred  to  as  a  correlational  study,  is  con-  retrospective if, relative to when the inves-
           ducted to establish that a relationship exists   tigator  begins  the  study,  the  events  under
           between  variables.  The  term  correlational   investigation  have  already  taken  place.  A
           refers to a method of analysis rather than a   study is prospective if the outcomes that are
           feature  of  the  design  itself.  Cross-sectional   being investigated have not yet taken place
           studies  are  useful  if  the  independent  vari-  when the study is initiated. Various hybrid
           able  is  an  enduring  personal  characteristic,   designs are also possible, referred to as ambi-
           for  instance,  gender  or  blood  type.  Cross-  directional  studies;  they  combine  features
           sectional studies are also useful for exploring   of  both  time  perspectives  (Aschengrau  &
           associations between and among variables.  Seage, 2008).
              Longitudinal  comparative  designs  are   As  in  experimental  research,  observa-
           usually  undertaken  to  explain  the  rela-  tional  research  designs  and  methods  are
           tionship  between  an  independent  variable   selected with the aim of minimizing bias. Bias
           and  an  outcome.  One  type  of  longitudinal,   refers to distortion in the result of a study. A
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