Page 1097 - Hematology_ Basic Principles and Practice ( PDFDrive )
P. 1097

Chapter 60  Myelodysplastic Syndromes  969.e11


            451.  Manoharan  A:  Low-dose  cytarabine  therapy  in  hypoplastic  acute   phase  II  clinical  trial  with  a  differentiation-inducing  agent.  Blood
                leukemia. N Engl J Med 309(26):1652–1653, 1983.       80(10):2604–2609, 1992.
            452.  Deeg  HJ,  Gotlib  J,  Beckham  C,  et al:  Soluble TNF  receptor  fusion   473.  Essers  MAG,  Offner  S,  Blanco-Bose  WE,  et al:  IFNalpha  activates
                protein (etanercept) for the treatment of myelodysplastic syndrome: a   dormant haematopoietic stem cells in vivo. Nature 458(7240):904–908,
                pilot study. Leukemia 16(2):162–164, 2002.            2009.
            453.  Rosenfeld  C,  Bedell  C:  Pilot  study  of  recombinant  human  soluble   474.  Walter D, Lier A, Geiselhart A, et al: Exit from dormancy provokes
                tumor  necrosis  factor  receptor  (TNFR:Fc)  in  patients  with  low  risk   DNA-damage-induced attrition in haematopoietic stem cells. Nature
                myelodysplastic syndrome. Leuk Res 26(8):721–724, 2002.  520:549–552, 2015.
            454.  Scott BL, Ramakrishnan A, Fosdal M, et al: Anti-thymocyte globulin   475.  List A, Beran M, DiPersio J, et al: Opportunities for Trisenox (arsenic
                plus  etanercept  as  therapy  for  myelodysplastic  syndromes  (MDS):  a   trioxide)  in  the  treatment  of  myelodysplastic  syndromes.  Leukemia
                phase II study. Br J Haematol 149(5):706–710, 2010.   17(8):1499–1507, 2003.
            455.  Stasi R, Amadori S: Infliximab chimaeric anti-tumour necrosis factor   476.  Schiller GJ, Slack J, Hainsworth JD, et al: Phase II multicenter study
                alpha monoclonal antibody treatment for patients with myelodysplastic   of arsenic trioxide in patients with myelodysplastic syndromes. J Clin
                syndromes. Br J Haematol 116(2):334–337, 2002.        Oncol 24(16):2456–2464, 2006.
            456.  Braun  T,  Fenaux  P:  Myelodysplastic  syndromes  (MDS)  and  auto-  477.  Bejanyan N, Tiu R, Raza A: A phase 2 trial of combination therapy
                immune  disorders  (AD):  cause  or  consequence?  Best  Pract  Res  Clin   with thalidomide, arsenic trioxide, dexamethasone, and ascorbic acid
                Haematol 26(4):327–336, 2013.                         (TADA)  in  patients  with  overlap  myelodysplastic/myeloproliferative
            457.  Biesma  DH,  van  den  Tweel  JG,  Verdonck  LF:  Immunosuppressive   neoplasms  (MDS/MPN)  or  primary  myelofibrosis  (PMF).  Cancer
                therapy for hypoplastic myelodysplastic syndrome. Cancer 79(8):1548–  118:3968–3976, 2012.
                1551, 1997.                                       478.  Sekeres MA, Maciejewski JP, Erba HP, et al: A Phase 2 study of com-
            458.  Molldrem  JJ,  Leifer  E,  Bahceci  E,  et al:  Antithymocyte  globulin  for   bination therapy with arsenic trioxide and gemtuzumab ozogamicin in
                treatment of the bone marrow failure associated with myelodysplastic   patients with myelodysplastic syndromes or secondary acute myeloid
                syndromes. Ann Intern Med 137(3):156–163, 2002.       leukemia. Cancer 117(6):1253–1261, 2011.
            459.  Saunthararajah Y, Nakamura R, Nam J-M, et al: HLA-DR15 (DR2)   479.  Hast R, Axdorph S, Laurén L, et al: Absent clinical effects of retinoic
                is  overrepresented  in  myelodysplastic  syndrome  and  aplastic  anemia   acid  and  isoretinoin  treatment  in  the  myelodysplastic  syndrome.
                and  predicts  a  response  to  immunosuppression  in  myelodysplastic   Hematol Oncol 7(4):297–301, 1989.
                syndrome. Blood 100(5):1570–1574, 2002.           480.  Ohno  R,  Naoe  T,  Hirano  M,  et al:  Treatment  of  myelodysplastic
            460.  Sloand EM, Wu CO, Greenberg P, et al: Factors affecting response and   syndromes with all-trans retinoic acid. Leukemia Study Group of the
                survival in patients with myelodysplasia treated with immunosuppres-  Ministry of Health and Welfare. Blood 81(5):1152–1154, 1993.
                sive therapy. J Clin Oncol 26(15):2505–2511, 2008.  481.  Schenk  T,  Chen  WC,  Göllner  S,  et al:  Inhibition  of  the  LSD1
            461.  Passweg JR, Giagounidis AAN, Simcock M, et al: Immunosuppressive   (KDM1A) demethylase reactivates the all-trans-retinoic acid differen-
                therapy for patients with myelodysplastic syndrome: a prospective ran-  tiation pathway in acute myeloid leukemia. Nat Med 18(4):605–611,
                domized multicenter phase III trial comparing antithymocyte globulin   2012.
                plus cyclosporine with best supportive care–SAKK 33/99. J Clin Oncol   482.  Search  of:  MDS  AND  (“low”  or  “intermediate”)  NOT  (“high-risk”  or
                29(3):303–309, 2011.                                  “AML” or “acute myeloid leukemia”) | Open Studies | Exclude Unknown |
            462.  Sloand  EM,  Olnes  MJ,  Shenoy  A,  et al:  Alemtuzumab  treatment  of   Adult | Phase 1, 2, 3 - List Results - ClinicalTrials.gov [Internet].
                intermediate-1  myelodysplasia  patients  is  associated  with  sustained   483.  Zhou L, Nguyen AN, Sohal D, et al: Inhibition of the TGF-beta recep-
                improvement in blood counts and cytogenetic remissions. J Clin Oncol   tor I kinase promotes hematopoiesis in MDS. Blood 112(8):3434–3443,
                28(35):5166–5173, 2010.                               2008.
            463.  Keyhani  A,  Jendiroba  DB,  Freireich  EJ:  Angiogenesis  and  leukemia.   484.  Quesnel  B,  Guillerm  G,  Vereecque  R,  et al:  Methylation  of  the
                Leuk Res 25(8):639–645, 2001.                         p15(INK4b)  gene  in  myelodysplastic  syndromes  is  frequent  and
            464.  Legros L, Slama B, Karsenti J-M, et al: Treatment of myelodysplastic   acquired  during  disease  progression.  Blood  91(8):2985–2990,
                syndromes with excess of blasts by bevacizumab is well tolerated and   1998.
                is  associated  with  a  decrease  of  VEGF  plasma  level.  Ann  Hematol   485.  Lin J, Yao D, Qian J, et al: Methylation status of fragile histidine triad
                91(1):39–46, 2012.                                    (FHIT)  gene  and  its  clinical  impact  on  prognosis  of  patients  with
            465.  Gupta  P,  Mulkey  F,  Hasserjian  RP,  et al:  A  phase  II  study  of  the   myelodysplastic syndrome. Leuk Res 32(10):1541–1545, 2008.
                oral  VEGF  receptor  tyrosine  kinase  inhibitor  vatalanib  (PTK787/  486.  Brakensiek K, Länger F, Schlegelberger B, et al: Hypermethylation of
                ZK222584)  in  myelodysplastic  syndrome:  Cancer  and  Leukemia   the  suppressor  of  cytokine  signalling-1  (SOCS-1)  in  myelodysplastic
                Group B study 10105 (Alliance). Invest New Drugs 31(5):1311–1320,   syndrome. Br J Haematol 130(2):209–217, 2005.
                2013.                                             487.  Liu TX, Becker MW, Jelinek J, et al: Chromosome 5q deletion and
            466.  Erikci AA, Ozturk A, Karagoz B, et al: Results of combination therapy   epigenetic suppression of the gene encoding alpha-catenin (CTNNA1)
                with  amifostine,  pentoxifylline,  ciprofloxacin  and  dexamethasone  in   in myeloid cell transformation. Nat Med 13(1):78–83, 2007.
                patients with myelodysplastic syndrome and acute myeloid leukemia.   488.  Shen L, Kantarjian H, Guo Y, et al: DNA methylation predicts survival
                Hematology 13(5):289–292, 2008.                       and response to therapy in patients with myelodysplastic syndromes. J
            467.  List AF: Emerging data on IMiDs in the treatment of myelodysplastic   Clin Oncol 28(4):605–613, 2010.
                syndromes (MDS). Semin Oncol 32(4 Suppl 5):S31–S35, 2005.  489.  Jones  PA,  Taylor  SM:  Cellular  differentiation,  cytidine  analogs  and
            468.  Vuylsteke J, Verloop MC, Drogendijk AC: Favourable effect of pyridox-  DNA methylation. Cell 20(1):85–93, 1980.
                ine and ascorbic acid in a patient with refractory sideroblastic anaemia   490.  de  Vos  D:  Epigenetic  drugs:  a  longstanding  story.  Semin  Oncol
                and haemochromatosis. Acta Med Scand 169:113–123, 1961.  32(5):437–442, 2005.
            469.  Nagler A, Rikilis I, Tatarsky I, et al: Effect of 1,25-dihydroxyvitamin   491.  Lyons RM, Cosgriff TM, Modi SS, et al: Hematologic response to three
                D3 and 13-cis-retinoic acid on in vitro hematopoiesis in the myelodys-  alternative dosing schedules of azacitidine in patients with myelodys-
                plastic syndromes. J Lab Clin Med 110(2):237–244, 1987.  plastic syndromes. J Clin Oncol 27(11):1850–1856, 2009.
            470.  Takami  A,  Nakao  S,  Ontachi  Y,  et al:  Successful  therapy  of  myelo-  492.  Silverman LR, Demakos EP, Peterson BL, et al: Randomized controlled
                dysplastic syndrome with menatetrenone, a vitamin K2 analog. Int J   trial of azacitidine in patients with the myelodysplastic syndrome: a study
                Hematol 69(1):24–26, 1999.                            of the cancer and leukemia group B. J Clin Oncol 20(10):2429–2440,
            471.  Tefferi  A,  Elliott  MA,  Steensma  DP,  et al:  Amifostine  alone  and  in   2002.
                combination with erythropoietin for the treatment of favorable myelo-  493.  Fenaux P, Mufti GJ, Hellstrom-Lindberg E, et al: Efficacy of azacitidine
                dysplastic syndrome. Leuk Res 25(2):183–185, 2001.    compared  with  that  of  conventional  care  regimens  in  the  treatment
            472.  Andreeff M, Stone R, Michaeli J, et al: Hexamethylene bisacetamide   of  higher-risk  myelodysplastic  syndromes:  a  randomised,  open-label,
                in  myelodysplastic  syndrome  and  acute  myelogenous  leukemia:  a   phase III study. Lancet Oncol 10(3):223–232, 2009.
   1092   1093   1094   1095   1096   1097   1098   1099   1100   1101   1102