Page 168 - Hematology_ Basic Principles and Practice ( PDFDrive )

126 Part II Cellular Basis of Hematology

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18. Chow A, et al: Bone marrow CD169 macrophages promote the reten- 28. Flynn CM, Kaufman DS: Donor cell leukemia: insight into cancer stem
tion of hematopoietic stem and progenitor cells in the mesenchymal stem cells and the stem cell niche. Blood 109:2688, 2007.
cell niche. J Exp Med 208:261, 2011. 29. Raaijmakers MH, et al: Bone progenitor dysfunction induces myelodys-
19. Bruns I, et al: Megakaryocytes regulate hematopoietic stem cell quies- plasia and secondary leukaemia. Nature 464:852, 2010.
cence through CXCL4 secretion. Nat Med 20:1315, 2014. 30. Colmone A, et al: Leukemic cells create bone marrow niches that disrupt
20. Katayama Y, et al: Signals from the sympathetic nervous system regu- the behavior of normal hematopoietic progenitor cells. Science 322:1861,
late hematopoietic stem cell egress from bone marrow. Cell 124:407, 2008.
2006. 31. Hanoun M, et al: Acute myelogenous leukemia-induced sympathetic
21. Yamazaki S, et al: Nonmyelinating Schwann cells maintain hematopoi- neuropathy promotes malignancy in an altered hematopoietic stem cell
etic stem cell hibernation in the bone marrow niche. Cell 147:1146, niche. Cell Stem Cell 15:365, 2014.
2011. 32. Nervi B, et al: Chemosensitization of acute myeloid leukemia (AML)
22. Spencer JA, et al: Direct measurement of local oxygen concentration in following mobilization by the CXCR4 antagonist AMD3100. Blood
the bone marrow of live animals. Nature 508:269, 2014. 113:6206, 2009.
23. Yu VW, et al: Specific bone cells produce DLL4 to generate thymus- 33. Jin L, Hope KJ, Zhai Q, et al: Targeting of CD44 eradicates human
seeding progenitors from bone marrow. J Exp Med 212:759, 2015. acute myeloid leukemic stem cells. Nat Med 12:1167, 2006.
24. Ninomiya M, et al: Homing, proliferation and survival sites of human 34. Matsunaga T, et al: Interaction between leukemic-cell VLA-4 and
leukemia cells in vivo in immunodeficient mice. Leukemia 21:136, 2007. stromal fibronectin is a decisive factor for minimal residual disease of
25. Notta F, et al: Isolation of single human hematopoietic stem cells capable acute myelogenous leukemia. Nat Med 9:1158, 2003.
of long-term multilineage engraftment. Science 333:218, 2011. 35. Jin L, et al: Monoclonal antibody-mediated targeting of CD123, IL-3
26. Sacchetti B, et al: Self-renewing osteoprogenitors in bone marrow sinu- receptor alpha chain, eliminates human acute myeloid leukemic stem
soids can organize a hematopoietic microenvironment. Cell 131:324, cells. Cell Stem Cell 5:31, 2009.
2007. 36. Majeti R, et al: CD47 is an adverse prognostic factor and therapeutic
27. Cutler C, et al: Prostaglandin-modulated umbilical cord blood hemato- antibody target on human acute myeloid leukemia stem cells. Cell
poietic stem cell transplantation. Blood 122:3074, 2013. 138:286, 2009.