Page 1880 - Hematology_ Basic Principles and Practice ( PDFDrive )
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1668.e4  Part X  Transplantation


        141.  Blazar BR, Sharpe AH, Chen AI, et al: Ligation of OX40 (CD134)   165.  Lowsky R, Takahashi T, Liu YP, et al: Protective conditioning for acute
            regulates  graft-versus-host  disease  (GVHD)  and  graft  rejection  in   graft-versus-host disease. N Engl J Med 353:1321, 2005.
            allogeneic bone marrow transplant recipients. Blood 101:3741, 2003.  166.  Edinger M, Hoffmann P, Contag CH, et al: Evaluation of effector cell
        142.  Blazar  BR,  Carreno  BM,  Panoskaltsis-Mortari  A,  et al:  Blockade  of   fate and function by in vivo bioluminescence imaging. Methods 31:172,
            programmed death-1 engagement accelerates graft-versus-host disease   2003.
            lethality  by  an  IFN-gamma-dependent  mechanism.  J  Immunol   167.  Nguyen VH, Zeiser R, Dasilva DL, et al: In vivo dynamics of regulatory
            171:1272, 2003.                                       T-cell  trafficking  and  survival  predict  effective  strategies  to  control
        143.  Nabekura T, Shibuya K, Takenaka E, et al: Critical role of DNAX acces-  graft-versus-host  disease  following  allogeneic  transplantation.  Blood
            sory molecule-1 (DNAM-1) in the development of acute graft-versus-  109:2649, 2007.
            host disease in mice. Proc Natl Acad Sci USA 107(43):18593–18598,   168.  Zhang  P,  Tey  S-K,  Koyama  M,  et al:  Induced  Regulatory  T  Cells
            2010.                                                 Promote Tolerance When Stabilized by Rapamycin and IL-2 In Vivo.
        144.  Koyama M, Kuns RD, Olver SD, et al: Promoting regulation via the   J Immunol 191(10):5291, 2013.
                                                                                                           +
            inhibition  of  DNAM-1  after  transplantation.  Blood  121(17):3511,   169.  Ma H, Lu C, Ziegler J, et al: Absence of Stat1 in donor CD4  T cells
            2013.                                                 promotes the expansion of Tregs and reduces graft-versus-host disease
                                                         +
                                                 +
        145.  Csencsits KL, Bishop DK: Contrasting alloreactive CD4  and CD8  T   in mice. J Clin Invest 121:2554, 2011.
            cells: there’s more to it than MHC restriction. Am J Transplant 3:107,   170.  Tawara I, Shlomchik WD, Jones A, et al: A crucial role for host APCs
                                                                                      +
                                                                                           +
            2003.                                                 in the induction of donor CD4 CD25  regulatory T cell-mediated sup-
        146.  Korngold R, Sprent J: Features of T cells causing H-2 restricted lethal   pression of experimental graft-versus-host disease. J Immunol 185:3866,
            graft-vs-host disease across minor histocompatibility barriers. J Exp Med   2010.
            155:872, 1982.                                    171.  Matsuoka K, Koreth J, Kim HT, et al: Low-dose interleukin-2 therapy
        147.  Korngold R, Sprent J: Surface markers of T cells causing lethal graft-vs-  restores regulatory T cell homeostasis in patients with chronic graft-
            host disease to class I vs class II H-2 differences. J Immunol 135:3004,   versus-host disease. Sci Transl Med 5:179ra43, 2013.
            1985.                                             172.  Choi  SW,  Braun T,  Chang  L,  et al:  Vorinostat  plus  tacrolimus  and
        148.  Korngold  R,  Sprent  J:  T  cell  subsets  and  graft-versus-host  disease.   mycophenolate to prevent graft-versus-host disease after related-donor
            Transplantation 44:335, 1987.                         reduced-intensity  conditioning  allogeneic  haemopoietic  stem-cell
        149.  Wu CJ, Ritz J: Induction of tumor immunity following allogeneic stem   transplantation: a phase 1/2 trial. Lancet Oncol 15(1):87, 2014.
            cell transplantation. Adv Immunol 90:133, 2006.   173.  Choi SW, Gatza E, Hou G, et al: Histone deacetylase inhibition regu-
                                                +
        150.  Anderson BE, McNiff J, Yan J, et al: Memory CD4  T cells do not   lates inflammation and enhances Tregs after allogeneic hematopoietic
            induce graft-versus-host disease. J Clin Invest 112:101, 2003.  cell transplantation in humans. Blood 125(5):815, 2015.
        151.  Chen BJ, Cui X, Sempowski GD, et al: Transfer of allogeneic CD62L-   174.  Kanakry CG, Ganguly S, Zahurak M, et al: Aldehyde dehydrogenase
            memory  T  cells  without  graft-versus-host  disease.  Blood  103:1534,   expression drives human regulatory T cell resistance to posttransplanta-
            2004.                                                 tion cyclophosphamide. Sci Transl Med 5:211ra157, 2013.
                                                         +
        152.  Zhang Y, Joe G, Zhu J, et al: Dendritic cell-activated CD44hiCD8  T   175.  Martelli  MF,  Di  Ianni  M,  Ruggeri  L,  et al:  HLA-haploidentical
            cells are defective in mediating acute graft-versus-host disease but retain   transplantation  with  regulatory  and  conventional  T-cell  adoptive
            graft-versus-leukemia activity. Blood 103:3970, 2004.  immunotherapy  prevents  acute  leukemia  relapse.  Blood  124(4):638,
        153.  Maeda  Y,  Tawara  I,  Teshima  T,  et al:  Lymphopenia-induced  pro-  2014.
            liferation  of  donor  T  cells  reduces  their  capacity  for  causing  acute   176.  Riley JL, June CH, Blazar BR: Human T regulatory cell therapy: take
            graft-versus-host disease. Exp Hematol 35:274, 2007.  a billion or so and call me in the morning. Immunity 30:656, 2009.
        154.  Taylor PA, Panoskaltsis-Mortari A, Swedin JM, et al: L-Selectin(hi) but   177.  Hashimoto D, Asakura S, Miyake S, et al: Host NKT cells promote
                              +
                                +
            not the L-selectin(lo) CD4 25  T-regulatory cells are potent inhibitors   Th2  polarization  of  donor  T  cells  and  regulate  acute  GVHD  after
            of GVHD and BM graft rejection. Blood 104:3804, 2004.  experimental  BMT  via  a  STAT6-dependent  mechanism.  Blood
        155.  Zhang  Y,  Joe  G,  Hexner  E,  et al:  Alloreactive  memory  T  cells  are   102:191a, 2003.
            responsible for the persistence of graft-versus-host disease. J Immunol   178.  Morris ES, MacDonald KP, Rowe V, et al: NKT cell-dependent leuke-
            174:3051, 2005.                                       mia eradication following stem cell mobilization with potent G-CSF
                                                +
        156.  Zhang Y, Joe G, Hexner E, et al: Host-reactive CD8  memory stem   analogs. J Clin Invest 115:3093, 2005.
            cells in graft-versus-host disease. Nat Med 11:1299, 2005.  179.  Morris  ES,  MacDonald  KP,  Hill  GR:  Stem  cell  mobilization  with
        157.  Blazar BR, Taylor PA: Regulatory T cells. Biol Blood Marrow Transplant   G-CSF  analogs:  a  rational  approach  to  separate  GVHD  and  GVL?
            11:46, 2005.                                          Blood 107:3430, 2006.
                                      +
        158.  Cohen JL, Boyer O: The role of CD4 CD25hi regulatory T cells in   180.  Banovic T, MacDonald KP, Morris ES, et al: TGF-beta in allogeneic
            the physiopathogeny of graft-versus-host disease. Curr Opin Immunol   stem cell transplantation: friend or foe? Blood 106:2206, 2005.
            18:580, 2006.                                     181.  Wang JW, Howson JM, Ghansah T, et al: Influence of SHIP on the
                                         +
        159.  Johnson BD, Konkol MC, Truitt RL: CD25  immunoregulatory T-cells   NK  repertoire  and  allogeneic  bone  marrow  transplantation.  Science
            of donor origin suppress alloreactivity after BMT. Biol Blood Marrow   295:2094, 2002.
            Transplant 8:525, 2002.                           182.  Kamradt T, Mitchison NA: Tolerance and autoimmunity. N Engl J Med
        160.  Hoffmann C, Chow KU, Wolf E, et al: Strong impact of highly active   344:655, 2001.
            antiretroviral therapy on survival in patients with human immunode-  183.  Wekerle T, Kurtz J, Ito H, et al: Allogeneic bone marrow transplantation
            ficiency  virus-associated  Hodgkin’s  disease.  Br  J  Haematol  125:455,   with co-stimulatory blockade induces macrochimerism and tolerance
            2004.                                                 without cytoreductive host treatment. Nat Med 6:464, 2000.
                                         +
                                               +
        161.  Cohen JL, Trenado A, Vasey D, et al: CD4( )CD25( ) immunoregula-  184.  Wekerle T: Transplantation tolerance induced by mixed chimerism. J
            tory T cells: new therapeutics for graft-versus-host disease. J Exp Med   Heart Lung Transplant 20:816, 2001.
            196:401, 2002.                                    185.  Sykes M, Sachs DH: Mixed chimerism. Philos Trans R Soc Lond B Biol
        162.  Roncarolo  MG:  The  role  of  interleukin-10  in  transplantation  and   Sci 356:707, 2001.
            GVHD. In Ferrara JLM, Deeg HJ, Burakoff SJ, editors: Graft-vs.-host   186.  Centers for Disease Control and Prevention, Infectious Diseases Society
            disease, ed 2, New York, 1997, Marcel Dekker, Inc., p 693.  of America, American Society of Blood and Marrow Transplantation:
        163.  Young KJ, DuTemple B, Phillips MJ, et al: Inhibition of graft-versus-  Guidelines for preventing opportunistic infections among hematopoi-
            host disease by double-negative regulatory T cells. J Immunol 171:134,   etic stem cell transplant recipients. Biol Blood Marrow Transplant 6:7,
            2003.                                                 2000.
                                                         −
        164.  Zeng D, Lewis D, Dejbakhsh-Jones S, et al: Bone marrow NK1.1( )   187.  Van  Parijs  L,  Ibraghimov  A,  Abbas  AK: The  roles  of  costimulation
                     +
            and  NK1.1( )  T  cells  reciprocally  regulate  acute  graft  versus  host   and Fas in T-cell apoptosis and peripheral tolerance. Immunity 4:321,
            disease. J Exp Med 189:1073, 1999.                    1996.
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