Page 1882 - Hematology_ Basic Principles and Practice ( PDFDrive )

1668.e6 Part X Transplantation

234. Sackstein R: A revision of Billingham’s tenets: the central role of lym- participation of perforin, Fas ligand, and the simultaneous inhibition
phocyte migration in acute graft-versus-host disease. Biol Blood Marrow of 3 tumor necrosis factor family effector pathways. Biol Blood Marrow
Transplant 12:2, 2006. Transplant 11:576, 2005.
235. Harada N, Takagi K, Baba K, et al: Biodegradation of diphenylarsinic 257. Schmaltz C, Alpdogan O, Kappel BJ, et al: T cells require TRAIL for
acid to arsenic acid by novel soil bacteria isolated from contaminated optimal graft-versus-tumor activity. Nat Med 8:1433, 2002.
soil. Biodegradation 21:491, 2010. 258. Sato K, Nakaoka T, Yamashita N, et al: TRAIL-transduced dendritic
236. van den Brink MR, Burakoff SJ: Cytolytic pathways in haematopoietic cells protect mice from acute graft-versus-host disease and leukemia
stem-cell transplantation. Nat Rev Immunol 2:273, 2002. relapse. J Immunol 174:4025, 2005.
237. Pan G, O’Rourke K, Chinnaiyan AM, et al: The receptor for the 259. Brown GR, Lee E, Thiele DL: TNF-TNFR2 interactions are critical
cytotoxic ligand TRAIL. Science 276:111, 1997. for the development of intestinal graft-versus-host disease in MHC
238. Chicheportiche Y, Bourdon PR, Xu H, et al: TWEAK, a new secreted class II-disparate (C57BL/6J–>C57BL/6J × bm12)F1 mice. J Immunol
ligand in the tumor necrosis factor family that weakly induces apoptosis. 168:3065, 2002.
J Biol Chem 272:32401, 1997. 260. Brown GR, Thiele DL: Enhancement of MHC class I-stimulated
239. Jiang S, Herrera O, Lechler RI: New spectrum of allorecognition alloresponses by TNF/TNF receptor (TNFR)1 interactions and of
pathways: implications for graft rejection and transplantation tolerance. MHC class II-stimulated alloresponses by TNF/TNFR2 interactions.
Curr Opin Immunol 16:550, 2004. Eur J Immunol 30:2900, 2000.
240. Jiang Z, Podack E, Levy R: Donor T cells which cannot mediate 261. Brown GR, Lee EL, El-Hayek J, et al: IL-12-independent LIGHT
+
perforin-dependent and FasL-dependent cytotoxicity can effect graft vs signaling enhances MHC class II disparate CD4 T cell alloprolifera-
host reactivity following allogeneic bone marrow transplantation. Period tion, IFN-gamma responses, and intestinal graft-versus-host disease. J
Biol 100:477, 1998. Immunol 174:4688, 2005.
241. Maeda Y, Levy RB, Reddy P, et al: Both perforin and Fas ligand are 262. Xu Y, Flies AS, Flies DB, et al: Selective targeting of the LIGHT-
+
required for the regulation of alloreactive CD8 T cells during acute HVEM co-stimulatory system for the treatment of graft-versus-host
graft-versus-host disease. Blood 105:2023, 2005. disease. Blood 2006.
242. Voskoboinik I, Smyth MJ, Trapani JA: Perforin-mediated target-cell 263. Akahoshi M, Takanashi M, Masuda M, et al: A case of transfusion-
death and immune homeostasis. Nat Rev Immunol 6:940, 2006. associated graft-versus-host disease not prevented by white cell-reduction
243. Baker MB, Altman NH, Podack ER, et al: The role of cell-mediated filters. Transfusion 32:169, 1992.
cytotoxicity in acute GVHD after MHC-matched allogeneic bone 264. Grau GE, Fajardo LF, Piguet PF, et al: Tumor necrosis factor (cachectin)
marrow transplantation in mice. J Exp Med 183:2645, 1996. as an essential mediator in murine cerebral malaria. Science 237:1210,
244. Braun MY, Lowin B, French L, et al: Cytotoxic T cells deficient in both 1987.
functional fas ligand and perforin show residual cytolytic activity yet 265. Bauer S, Groh V, Wu J, et al: Activation of NK cells and T cells by
lose their capacity to induce lethal acute graft-versus-host disease. J Exp NKG2D, a receptor for stress-inducible MICA. Science 285:727, 1999.
Med 183:657, 1996. 266. Hill GR, Teshima T, Rebel VI, et al: The p55 TNF-alpha receptor plays
245. Baker MB, Riley RL, Podack ER, et al: Graft-versus-host-disease- a critical role in T cell alloreactivity. J Immunol 164:656, 2000.
associated lymphoid hypoplasia and B cell dysfunction is dependent 267. Grau GE, Bieler G, Pointaire P, et al: Significance of cytokine produc-
upon donor T cell-mediated Fas-ligand function, but not perforin tion and adhesion molecules in malarial immunopathology. Immunol
function. Proc Natl Acad Sci USA 94:1366, 1997. Lett 25:189, 1990.
246. Graubert TA, Russell JH, Ley TJ: The role of granzyme B in murine 268. Tanaka J, Imamura M, Kasai M, et al: Cytokine gene expression in
models of acute graft-versus-host disease and graft rejection. Blood peripheral blood mononuclear cells during graft-versus-host disease
87:1232, 1996. after allogeneic bone marrow transplantation. Br J Haematol 85:558,
247. Graubert TA, DiPersio JF, Russell JH, et al: Perforin/granzyme- 1993.
dependent and independent mechanisms are both important for the 269. Abhyankar S, Gilliland DG, Ferrara JL: Interleukin-1 is a critical
development of graft-versus-host disease after murine bone marrow effector molecule during cytokine dysregulation in graft versus host
transplantation. J Clin Invest 100:904, 1997. disease to minor histocompatibility antigens. Transplantation 56:1518,
248. Przepiorka D, Saliba R, Cleary K, et al: Tacrolimus does not abrogate 1993.
the increased risk of acute graft-versus-host disease after unrelated- 270. Barrett JC, Lee JC, Lees CW, et al: Genome-wide association study of
donor marrow transplantation with allelic mismatching at HLA-DRB1 ulcerative colitis identifies three new susceptibility loci, including the
and HLA-DQB1. Biol Blood Marrow Transplant 6:190, 2000. HNF4A region. Nat Genet 41:1330, 2009.
249. Aggarwal BB: Signalling pathways of the TNF superfamily: a double- 271. Antin JH, Weisdorf D, Neuberg D, et al: Interleukin-1 blockade does
edged sword. Nat Rev Immunol 3:745, 2003. not prevent acute graft-versus-host disease: results of a randomized,
250. Via C, Nguyen P, Shustov A, et al: A major role for the Fas pathway in double-blind, placebo-controlled trial of interleukin-1 receptor antago-
acute graft-versus-host disease. J Immunol 157:5387, 1996. nist in allogeneic bone marrow transplantation. Blood 100:3479, 2002.
251. Hattori K, Hirano T, Miyajima H, et al: Differential effects of anti-Fas 272. Falzarano G, Krenger W, Snyder KM, et al: Suppression of B-cell
ligand and anti-tumor necrosis factor alpha antibodies on acute graft- proliferation to lipopolysaccharide is mediated through induction of
versus-host disease pathologies. Blood 91:4051, 1998. the nitric oxide pathway by tumor necrosis factor-alpha in mice with
252. van den Brink MR, Moore E, Ferrara JL, et al: Graft-versus-host- acute graft-versus-host disease. Blood 87:2853, 1996.
disease-associated thymic damage results in the appearance of T cell 273. Nestel FP, Greene RN, Kichian K, et al: Activation of macrophage
clones with anti-host reactivity. Transplantation 69:446, 2000. cytostatic effector mechanisms during acute graft-versus-host disease:
253. Lin T, Brunner T, Tietz B, et al: Fas ligand-mediated killing by intestinal release of intracellular iron and nitric oxide-mediated cytostasis. Blood
intraepithelial lymphocytes. Participation in intestinal graft-versus-host 96:1836, 2000.
disease. J Clin Invest 101:570, 1998. 274. Dejbakhsh-Jones S, Jerabek L, Weissman IL, et al: Extrathymic matura-
254. Liem LM, van Lopik T, van Nieuwenhuijze AEM, et al: Soluble fas tion of ab T cells from hemopoietic stem cells. J Immunol 155:3338,
levels in sera of bone marrow transplantation recipients are increased 1995.
during acute graft-versus-host disease but not during infections. Blood 275. Billiar TR, Hoffman RA, Curran RD, et al: A role for inducible nitric
91:1464, 1998. oxide biosynthesis in the liver in inflammation and in the allogeneic
255. Das H, Imoto S, Murayama T, et al: Levels of soluble FasL and FasL immune response. J Lab Clin Med 120:192, 1992.
gene expression during the development of graft-versus-host disease in 276. Bogdan C: Nitric oxide and the immune response. Nat Immunol 2:907,
DLT-treated patients. Br J Haematol 104:795, 1999. 2001.
256. Zimmerman Z, Shatry A, Deyev V, et al: Effector cells derived from 277. Tawara I, Koyama M, Liu C, et al: Interleukin-6 modulates graft-
host CD8 memory T cells mediate rapid resistance against minor his- versus-host responses after experimental allogeneic bone marrow
tocompatibility antigen-mismatched allogeneic marrow grafts without transplantation. Clin Cancer Res 17:77, 2011.