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1898  Part XII:  Hemostasis and Thrombosis   Chapter 112:  Platelet Morphology, Biochemistry, and Function           1899




                    871.  Zhu J, et al: The structure of a receptor with two associating transmembrane domains     905.  Calderwood DA, et al: The talin head domain binds to integrin beta subunit cytoplas-
                     on the cell surface: Integrin alphaIIbbeta3. Mol Cell 34(2):234–249, 2009.  mic tails and regulates integrin activation. J Biol Chem 274:28071–28074, 1999.
                    872.  Kim M, Carman CV, Springer TA: Bidirectional transmembrane signaling by cyto-    906.  Cowan KJ, Law DA, Phillips DR: Identification of shc as the primary protein binding
                     plasmic domain separation in integrins. Science 301(5640):1720–1725, 2003.  to the tyrosine-phosphorylated beta 3 subunit of alpha IIbbeta 3 during outside-in
                    873.  Li W, et al: A push-pull mechanism for regulating integrin function. Proc Natl Acad Sci   integrin platelet signaling. J Biol Chem 275(46):36423–36429, 2000.
                     U S A 102(5):1424–1429, 2005.                        907.  Eigenthaler M, et al: A conserved sequence motif in the integrin beta3 cytoplasmic
                    874.  Luo BH, et al: Disrupting integrin transmembrane domain heterodimerization   domain is required for its specific interaction with beta3-endonexin.  J Biol Chem
                     increases ligand binding affinity, not valency or clustering. Proc Natl Acad Sci U S A   272(12):7693–7698, 1997.
                     102(10):3679–3684, 2005.                             908.  Hannigan GE, et al: Regulation of cell adhesion and anchorage-dependent growth by
                    875.  Partridge  AW, et  al:  Transmembrane  domain  helix  packing  stabilizes  integrin   a new beta 1-integrin-linked protein kinase. Nature 379(6560):91–96, 1996.
                     alphaIIbbeta3 in the low affinity state. J Biol Chem 280(8):7294–7300, 2005.    909.  Loh E, Qi W, Vilaire G, Bennett JS: Effect of cytoplasmic domain mutations on the
                    876.  Leisner TM, et al: Bidirectional transmembrane modulation of integrin alphaIIbbeta3   agonist-stimulated ligand binding activity of the platelet integrin alphaIIbbeta3. J Biol
                     conformations. J Biol Chem 274(18):12945–12949, 1999.  Chem 271(47):30233–30241, 1966.
                    877.  Vinogradova O, et al: A Structural mechanism of integrin alpha(IIb)beta(3) “inside-    910.  Law DA, Nannizzi-Alaimo L, Phillips DR: Outside-in integrin signal transduction.
                     out” activation as regulated by its cytoplasmic face. Cell 110(5):587.  Alpha IIb beta 3-(GP IIb IIIa) tyrosine phosphorylation induced by platelet aggrega-
                    878.  Xiong JP, Stehle T, Goodman SL, Arnaout MA: A novel adaptation of the integrin   tion. J Biol Chem 271(18):10811–10815, 1996.
                     PSI domain revealed from its crystal structure. J Biol Chem 279(39):40252–40254,       911.  Leung-Hagesteijn CY, et al: Cell attachment to extracellular matrix substrates is
                     2004.                                                  inhibited upon downregulation of expression of calreticulin, an intracellular integrin
                    879.  Du X, et al: Long range propagation of conformational changes in integrin alpha IIb   alpha-subunit-binding protein. J Cell Sci 107(Pt 3):589–600, 1994.
                     beta 3. J Biol Chem 268(31):23087–23092, 1993 [published erratum appears in J Biol     912.  Naik UP, Patel PM, Parise LV: Identification of a novel calcium-binding protein
                     Chem 269(15):11673, 1994].                             that interacts with the integrin alphaIIb cytoplasmic domain. J Biol Chem 272(8):
                    880.  Frelinger AL 3ed, Du XP, Plow EF, Ginsberg MH: Monoclonal antibodies to lig-  4651–4654, 1997.
                     and-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter     913.  Otey CA, Pavalko FM, Burridge K: An interaction between alpha-actinin and the beta
                     receptor affinity, specificity, and function. J Biol Chem 266:17106–17111, 1991.  1 integrin subunit in vitro. J Cell Biol 111(2):721–729, 1990.
                    881.  Kamata T, et al: Critical cysteine residues for regulation of integrin alphaIIbbeta3 are     914.  Reddy KB, et al: Identification of an interaction between the m-band protein skelemin
                     clustered in the epidermal growth factor domains of the beta3 subunit. Biochem J   and beta-integrin subunits. Colocalization of a skelemin-like protein with beta1- and
                     378(Pt 3):1079–1082, 2004.                             beta3-integrins in non-muscle cells. J Biol Chem 273(52):35039–35047, 1998.
                    882.  Kashiwagi H, et al: A mutation in the extracellular cysteine-rich repeat region of     915.  Rojiani MV, et al: In vitro interaction of a polypeptide homologous to human Ro/SS-A
                     the beta3 subunit activates integrins alphaIIbbeta3 and alphaVbeta3.  Blood 93(8):   antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic
                     2559–2568, 1999.                                       domain of integrin alpha subunits. Biochemistry 30(41):9859–9866, 1991.
                    883.  Essex DW: The role of thiols and disulfides in platelet function. Antioxid Redox Signal     916.  Schaller MD, et al: Focal adhesion kinase and paxillin bind to peptides mimicking
                     6(4):736–746, 2004.                                    beta integrin cytoplasmic domains. J Cell Biol 130(5):1181–1187, 1995.
                    884.  Zucker MB, Masiello NC: Platelet aggregation caused by dithiothreitol.  Thromb       917.  Shattil SJ, et al: Beta 3-endonexin, a novel polypeptide that interacts specifically with
                     Haemost 51(1):119–124, 1984.                           the cytoplasmic tail of the integrin beta 3 subunit. J Cell Biol 131(3):807–816, 1995.
                    885.  Chen K, Detwiler TC, Essex DW: Characterization of protein disulphide isomerase     918.  Shock DD, et al: Calcium-dependent properties of CIB binding to the integrin
                     released from activated platelets. Br J Haematol 90(2):425–431, 1995.  alphaIIb cytoplasmic domain and translocation to the platelet cytoskeleton. Biochem
                    886.  Essex DW, Chen K, Swiatkowska M: Localization of protein disulfide isomerase to the   J 342(Pt 3):729–735, 1999.
                     external surface of the platelet plasma membrane. Blood 86(6):2168–2173, 1995.    919.  Zent R, et al: Class- and splice variant-specific association of CD98 with integrin beta
                    887.  Essex DW, Li M: Redox control of platelet aggregation. Biochemistry 42(1):129–136,   cytoplasmic domains. J Biol Chem 275(7):5059–5064, 2000.
                     2003.                                                920.  Naik UP, Eckfeld K: Junctional adhesion molecule 1 (JAM-1). J Biol Regul Homeost
                    888.  Mor-Cohen R, et al: Disulfide bond exchanges in integrins alphaIIbbeta3 and   Agents 17(4):341–347, 2003.
                     alphavbeta3 are required for activation and post-ligation signaling during clot retrac-    921.  Ming Z, et al: Lyn and PECAM-1 function as interdependent inhibitors of platelet
                     tion. Thromb Res 133(5):826–836, 2014.                 aggregation. Blood 117(14):3903–3906, 2011.
                    889.  O’Neill S, et al: The platelet integrin alpha IIbbeta 3 has an endogenous thiol isomerase     922.  Tourdot  BE,  et  al:  Immunoreceptor  tyrosine-based  inhibitory  motif  (ITIM)-
                     activity. J Biol Chem 275(47):36984–36990, 2000.       mediated inhibitory signaling is regulated by sequential phosphorylation mediated by
                    890.  Furie  B,  Flaumenhaft  R:  Thiol  isomerases  in  thrombus  formation.  Circ Res   distinct nonreceptor tyrosine kinases: A case study involving PECAM-1. Biochemistry
                     114(7):1162–1173, 2014.                                52(15):2597–2608, 2013.
                    891.  Wang L, et al: Platelet-derived ERp57 mediates platelet incorporation into a growing     923.  Scarborough RM, et al: Design of potent and specific integrin antagonists. Peptide antag-
                     thrombus by regulation of the alphaIIbbeta3 integrin. Blood 122(22):3642–3650, 2013.  onists with high specificity for glycoprotein IIb-IIIa. J Biol Chem 268:1066–1073, 1993.
                    892.  Provasi D, Negri A, Coller BS, Filizola M: Talin-driven inside-out activation mech-    924.  Beer JH, Springer KT, Coller BS: Immobilized Arg-Gly-Asp (RGD) peptides of vary-
                     anism of platelet αIIbβ3 integrin probed by multimicrosecond, all-atom molecular   ing lengths as structural probes of the platelet GPIIb/IIIa receptor. Blood 79:117–128,
                     dynamics simulations. Proteins 82(12):3231–3240, 2014.  1992.
                    893.  Gottschalk KE: A coiled-coil structure of the alphaIIbbeta3 integrin transmembrane     925.  Luo BH, Springer TA, Takagi J: Stabilizing the open conformation of the integrin
                     and cytoplasmic domains in its resting state. Structure 13(5):703–712, 2005.  headpiece with a glycan wedge increases affinity for ligand. Proc Natl Acad Sci U S A
                    894.  Lau TL, Kim C, Ginsberg MH, Ulmer TS: The structure of the integrin alphaIIb-  100(5):2403–2408, 2003.
                     beta3 transmembrane complex explains integrin transmembrane signalling. EMBO     926.  Heilmann E, et al: Thrombin-induced platelet aggregates have a dynamic structure:
                     J 28(9):1351–1361, 2009.                               Time-dependent redistribution of GPIIb/IIIa complexes and secreted adhesive pro-
                    895.  Luo BH, Springer TA, Takagi J: A specific interface between integrin transmembrane   teins. Arterioscler Thromb 11:704–718, 1991.
                     helices and affinity for ligand. PLoS Biol 2(6):776–786, 2004.    927.  Isenberg WM, McEver RP, Phillips DR, et al: The platelet fibrinogen receptor: An
                    896.  Wegener KL, et al: Structural basis of integrin activation by talin. Cell 128(1):171–182,   immunogold-surface replica study of agonist-induced ligand binding and receptor
                     2007.                                                  clustering. J Cell Biol 104(6):1655–1663, 1987.
                    897.  Hernandez-Campo PM, et al: Comparative analysis of different flow cytometry-based     928.  Prevost N, Shattil SJ: Outside-in signaling by integrin αIIbβ3, in Platelets, edited by
                     immunophenotypic methods for the analysis of CD59 and CD55 expression on major   AD Michelson, pp 347–350. Academic Press, San Diego, 2007.
                     peripheral blood cell subsets. Cytometry 50(3):191–201, 2002.    929.  Asch E, Podack E: Vitronectin binds to activated human platelets and plays a role in
                    898.  Robb L, et al: Molecular characterisation of mouse and human TSSC6: Evidence that   platelet aggregation. J Clin Invest 85(5):1372–1378, 1990.
                     TSSC6 is a genuine member of the tetraspanin superfamily and is expressed specifi-    930.  Haverstick DM, et al: Inhibition of platelet adhesion to fibronectin, fibrinogen,
                     cally in haematopoietic organs. Biochim Biophys Acta 1522(1):31–41, 2001.  and von Willebrand factor substrates by a synthetic tetrapeptide derived from the
                    899.  Hughes PE, et al: Breaking the integrin hinge. A defined structural constraint regu-  cell-binding domain of fibronectin. Blood 66:946–952, 1990, 1985.
                     lates integrin signaling. J Biol Chem 271(12):6571–6574, 1996.    931.  Plow EF, D’Souza SE, Ginsberg MH: Ligand binding to GPIIb-IIIa: A status report.
                    900.  Anthis NJ, Wegener KL, Ye F, et al: The structure of an integrin/talin complex reveals   Semin Thromb Hemost 18(3):324–332, 1992.
                     the basis of inside-out signal transduction. EMBO J 28(22):3623–3632, 2009.    932.  Weiss HJ, et al: Fibrinogen-independent platelet adhesion and thrombus formation on
                    901.  Ithychanda SS, Das M, Ma YQ, et al: Migfilin, a molecular switch in regulation of   subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate. J Clin
                     integrin activation. J Biol Chem 284(7):4713–4722, 2009.  Invest 83:288–297, 1989.
                    902.  Jenkins AL, et al: Tyrosine phosphorylation of the beta3 cytoplasmic domain mediates     933.  Schullek J, Jordan J, Montgomery RR: Interaction of  von  Willebrand factor with
                     integrin-cytoskeletal interactions. J Biol Chem 273(22):13878–13885, 1998.  human platelets in the plasma milieu. J Clin Invest 73:421–428, 1984.
                    903.  Jones CI, et al: Integrin-linked kinase regulates the rate of platelet activation and is     934.  Ni H, et al: Persistence of platelet thrombus formation in arterioles of mice lacking
                     essential for the formation of stable thrombi. J Thromb Haemost 12(8):1342–1352,   both von Willebrand factor and fibrinogen. J Clin Invest 106(3):385–392, 2000.
                     2014.                                                935.  Ni H, et al: Control of thrombus embolization and fibronectin internalization by
                    904.  Calderwood DA, Shattil SJ, Ginsberg MH: Integrins and actin filaments: Reciprocal   integrin alpha IIb beta 3 engagement of the fibrinogen gamma chain. Blood 102(10):
                     regulation of cell adhesion and signaling. J Biol Chem 275(30):22607–22610, 2000.  3609–3614, 2003.







          Kaushansky_chapter 112_p1829-1914.indd   1899                                                                 17/09/15   3:30 pm
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