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1898 Part XII: Hemostasis and Thrombosis Chapter 112: Platelet Morphology, Biochemistry, and Function 1899
799. McMorran BJ, et al: Platelets kill intraerythrocytic malarial parasites and mediate sur- 838. Hato T, Pampori N, Shattil SJ: Complementary roles for receptor clustering and con-
vival to infection. Science 323(5915):797–800, 2009. formational change in the adhesive and signaling functions of integrin alphaIIb beta3.
800. Boulaftali Y, et al: Platelet immunoreceptor tyrosine-based activation motif (ITAM) J Cell Biol 141(7):1685–1695, 1998.
signaling and vascular integrity. Circ Res 114(7):1174–1184, 2014. 839. Carrell NA, et al: Structure of human platelet membrane glycoproteins IIb and IIIa as
801. Lopez JA: The platelet glycoprotein Ib-IX complex. Blood Coagul Fibrinolysis 5(1): determined by electron microscopy. J Biol Chem 260:1743–1749, 1985.
97–119, 1994. 840. Weisel JW, et al: Examination of the platelet membrane glycoprotein IIb-IIIa complex
802. Wu G, et al: Human endothelial cells in culture and in vivo express on their surface all and its interaction with fibrinogen and other ligands by electron microscopy. J Biol
four components of the glycoprotein Ib/IX/V complex. Blood 90(7):2660–2669, 1997. Chem 267(23):16637–16643, 1992.
803. Hynes RO, Integrins: Bidirectional, allosteric signaling machines. Cell 110(6): 841. Arnaout M, Goodman S, Xiong J: Coming to grips with integrin binding to ligands.
673–687, 2002. Curr Opin Cell Biol 14(5):641–651, 2002.
804. Kasirer-Friede A, Kahn ML, Shattil SJ: Platelet integrins and immunoreceptors. 842. Arnaout MA: Integrin structure: New twists and turns in dynamic cell adhesion.
Immunol Rev 218:247–264, 2007. Immunol Rev 2002;186(1):125–140, 2002.
805. Bennett JS, Berger BW, Billings PC: The structure and function of platelet integrins. J 843. Takagi J, et al: Global conformational rearrangements in integrin extracellular
Thromb Haemost 7 Suppl 1:200–205, 2009. domains in outside-in and inside-out signaling. Cell 110:599–607, 2002.
806. Bledzka K, Smyth SS, Plow EF: Integrin alphaIIbbeta3: From discovery to efficacious 844. Xiong JP, et al: Crystal structure of the extracellular segment of integrin alphaVbeta3.
therapeutic target. Circ Res 112(8):1189–1200, 2013. Science 294(5541):339–345, 2001.
807. Phillips DR, et al: The platelet membrane glycoprotein IIb-IIIa complex. Blood 845. Xiong JP, et al: Crystal structure of the extracellular segment of integrin alpha Vbeta3
71:831–843, 1988. in complex with an Arg-Gly-Asp ligand. Science 296(5565):151–155, 2002.
808. Plow EF, Ginsberg MH: Cellular adhesion: GPIIb-IIIa as a prototypic adhesion recep- 846. Blue R, et al: Effects of limiting extension at the alphaIIb genu on ligand binding to
tor. Prog Hemost Thromb 9:117–156, 1989. integrin alphaIIbbeta3. J Biol Chem 285(23):17604–17613, 2010.
809. Ruggeri ZM: Structure and function of von Willebrand factor. Thromb Haemost 847. Cheng M, Li J, Negri A, Coller BS: Swing-out of the beta3 hybrid domain is required
82:576–584, 1999. for alphaIIbbeta3 priming and normal cytoskeletal reorganization, but not adhesion
810. Savage B, Ruggeri ZM: Platelet thrombus formation in flowing blood, in Platelets, to immobilized fibrinogen. PLoS One 8(12):e81609, 2013.
edited by AD Michelson, p 215. Academic Press, San Diego, 2002. 848. Choi WS, et al: Three-dimensional reconstruction of intact human integrin
811. Wagner CL, et al: Analysis of GPIIb/IIIa receptor number by quantification of 7E3 alphaIIbbeta3: New implications for activation-dependent ligand binding. Blood
binding to human platelets. Blood 88:907–914, 1996. 2013;122(26):4165–4171, 2013.
812. Zhou YF, et al: Sequence and structure relationships within von Willebrand factor. 849. Eng ET, et al: Intact alphaIIbbeta3 integrin is extended after activation as measured by
Blood 120(2):449–458, 2012. solution X-ray scattering and electron microscopy. J Biol Chem 286(40):35218–35226,
813. Cramer ER, et al: α Granule pool of glycoprotein IIb-IIIa in normal and pathologic 2011.
platelets and megakaryocytes. Blood 75:1220–1227, 1990. 850. Kamata T, et al: Structural requirements for activation in alphaIIb beta3 integrin. J
814. Woods VL Jr, Wolff LE, Keller DM: Resting platelets contain a substantial centrally Biol Chem 285(49):38428–38437, 2010.
located pool of glycoprotein IIb-IIIa complexes which may be accessible to some but 851. Nogales A, et al: Three-dimensional model of human platelet integrin alphaIIb beta3 in
not other extracellular proteins. J Biol Chem 261:15242–15251, 1986. solution obtained by small angle neutron scattering. J Biol Chem 285(2):1023–1031, 2010.
815. Youssefian T, et al: Platelet and megakaryocyte dense granules contain glycoproteins 852. Ye F, et al: Recreation of the terminal events in physiological integrin activation. J Cell
Ib and IIb-IIIa. Blood 89(11):4047–4057, 1997. Biol 188(1):157–173, 2010.
816. Peerschke EI: The platelet fibrinogen receptor. Semin Hematol 22(4):241–259, 1985. 853. Zhu J, et al: Structure-guided design of a high affinity platelet integrin αIIbβ3 receptor
817. Wencel-Drake JD: Plasma membrane GPIIb/IIIa. Evidence for a cycling receptor antagonist that disrupts Mg2+ binding to the MIDAS. Sci Transl Med 4:1–12, 2012.
pool. Am J Clin Pathol 136:61–70, 1990. 854. Poncz M, et al: Structure of the platelet membrane glycoprotein IIb. Homology to the
818. Harrison P: Platelet α-granular fibrinogen. Platelets 3:1–10, 1992. alpha subunits of the vitronectin and fibronectin membrane receptors. J Biol ChemJ
819. Hynes RO: Integrins: A family of cell surface receptors. Cell 48:549–554, 1987. Biol Chem 262(18):8476–8482, 1987.
820. Ruoslahti E: Fibronectin and its receptors. Annu Rev Biochem 57:375–413, 1988. 855. Fitzgerald LA, et al: Protein sequence of endothelial glycoprotein IIIa derived from a
821. Doolittle RF, et al: The amino acid sequence of the alpha-chain of human fibrinogen. cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin.” J Biol
Nature 280:464, 1979. Chem 262(9):3936–3939, 1987.
822. Cheresh DA, et al: Recognition of distinct adhesive sites on fibrinogen by related inte- 856. Bray PF, et al: Physical linkage of the genes for platelet membrane glycoproteins IIb
grins on platelets and endothelial cells. Cell 58:945–953, 1988, 1989. and IIIa. Proc Natl Acad Sci U S A 85(22):8683–8687, 1988.
823. Farrell DH, Thiagarajan P: Binding of recombinant fibrinogen mutants to platelets. J 857. Thornton MA, et al: The human platelet alphaIIb gene is not closely linked to its inte-
Biol Chem 269(1):226–231, 1994. grin partner beta3. Blood 94(6):2039–2047, 1999.
824. Farrell DH, et al: Role of fibrinogen α and γ chain sites in platelet aggregation. Proc 858. Steiner B, et al: Ca+2 dependent structural transitions of the platelet glycoprotein IIb-
Natl Acad Sci U S A 89(22):10729–10732, 1992. IIIa complex. Preparation of stable glycoprotein IIb and IIIa monomers. J Biol Chem
825. Savage B, Ruggeri ZM: Selective recognition of adhesive sites in surface-bound 266:14986–14991, 1991.
fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets. J Biol Chem 266(17): 859. Mitchell WB, et al: AlphaIIbbeta3 biogenesis is controlled by engagement of alphaIIb
11227–11233, 1991. in the calnexin cycle via the N15-linked glycan. Blood 107(7):2713–2719, 2006.
826. Springer TA, Zhu J, Xiao T: Structural basis for distinctive recognition of fibrinogen 860. Duperray A, et al: Biosynthesis and assembly of platelet GPIIb-IIIa in human
gammaC peptide by the platelet integrin alphaIIbbeta3. J Cell Biol 182(4):791–800, megakaryocytes: Evidence that assembly between pro-GPIIb and GPIIIa is a prereq-
2008. uisite for expression of the complex on the cell surface. Blood 74:1603–1611, 1989.
827. Xiao T, et al: Structural basis for allostery in integrins and binding to fibrinogen-mi- 861. O’Toole TE, et al: Efficient surface expression of platelet GPIIb-IIIa requires both sub-
metic therapeutics. Nature 432:59–67, 2004. units. Blood 74(1):14–18, 1989.
828. Goldsmith HL, et al: Time and force dependence of the rupture of glycoprotein 862. McEver RP, Baenziger JU, Majerus PW: Isolation and structural characterization of
IIb-IIIa-fibrinogen bonds between latex spheres. Biophys J 78(3):1195–1206, 2000. the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets.
829. Hsieh CF, et al: Stepped changes of monovalent ligand-binding force during lig- Blood 59:80.
and-induced clustering of integrin alphaIIB beta3. J Biol Chem 281(35):25466–25474, 863. Haas TA, Plow EF: The cytoplasmic domain of alphaIIb beta3. A ternary com-
2006. plex of the integrin alpha and beta subunits and a divalent cation. J Biol Chem
830. Huber W, et al: Determination of kinetic constants for the interaction between the 1996;271(11):6017–6026, 1982.
platelet glycoprotein IIb-IIIa and fibrinogen by means of surface plasmon resonance. 864. Kim C, Lau TL, Ulmer TS, Ginsberg MH: Interactions of platelet integrin alphaIIb
Eur J Biochem 227(3):647–656, 1995. and beta3 transmembrane domains in mammalian cell membranes and their role in
831. Litvinov RI, et al: Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 integrin activation. Blood 113(19):4747–4753, 2009.
detected using force spectroscopy. Biophys J 89(4):2824–2834, 2005. 865. Muir TW, et al: Design and chemical synthesis of a neoprotein structural model for
832. Muller B, et al: Two-step binding mechanism of fibrinogen to alpha IIb beta 3 integrin the cytoplasmic domain of a multisubunit cell-surface receptor: Integrin alpha IIb
reconstituted into planar lipid bilayers. J Biol Chem 268(9):6800–6808, 1993. beta 3 (platelet GPIIb-IIIa). Biochemistry 33(24):7701–7708, 1994.
833. Peerschke EI: Reversible and irreversible binding of fibrinogen to platelets. Platelets 866. Vallar L, et al: Divalent cations differentially regulate integrin alphaIIb cytoplasmic
8(5):311–317, 1997. tail binding to beta3 and to calcium- and integrin-binding protein. J Biol Chem
834. Wencel-Drake JD, et al: Internalization of bound fibrinogen modulates platelet aggre- 274(24):17257–17266, 1999.
gation. Blood 87(2):602–612, 1996. 867. Hughes PE, et al: Breaking the integrin hinge. A defined structural constraint regu-
835. Peerschke EIB: Events occurring after thrombin-induced fibrinogen binding to plate- lates integrin signaling. J Biol Chem 271(12):6571–6574, 1996.
lets. Semin Thromb Hemost 18:34–43, 1992. 868. Li A, et al: Integrin alphaII b tail distal of GFFKR participates in inside-out alphaII b
836. Ugarova TP, et al: Conformational changes in fibrinogen elicited by its interaction beta3 activation. J Thromb Haemost 12(7):1145–1155, 2014.
with platelet membrane glycoprotein GPIIb-IIIa. J Biol Chem 268:21080–21087, 1993. 869. O’Toole TE, et al: Integrin cytoplasmic domains mediate inside-out signal transduc-
837. Zamarron C, Ginsberg MH, Plow EF: A receptor-induced binding site in fibrinogen tion. J Cell Biol 124(6):1047–1059, 1994.
elicited by its interaction with platelet membrane glycoprotein IIb-IIIa. J Biol Chem 870. O’Toole TE, et al: Modulation of the affinity of integrin αIIbβ3 (GPIIb-IIIa) by the
266:17106–17111, 1991. cytoplasmic domain of alpha IIb. Science 254(5033):845–847, 1991.
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