Page 2006 - Williams Hematology ( PDFDrive )
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1980 Part XII: Hemostasis and Thrombosis Chapter 115: Vascular Function In Hemostasis 1981
87. Isermann B, Hendrickson SB, Hutley K, et al: Tissue-restricted expression of thrombo- 121. Thompson EA, Nelles L, Collen D: Effect of retinoic acid on the synthesis of tissue-type
modulin in the placenta rescues thrombomodulin-deficient mice from early lethality plasminogen activator and plasminogen activator inhibitor 1 in human endothelial
and reveals a secondary developmental block. Development 128:827–838, 2001. cells. Eur J Biochem 201:627–632, 1991.
88. Isermann B, Hendrickson SB, Zogg M, et al: Endothelium-specific loss of muine 122. Bulens F, Ibanez-Tallon I, Van Acker P, et al: Retinoic acid induction of human tissue-
thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-on- type plasminogen activator gene expression via a direct repeat element (DR5) located
set thrombosis. J Clin Invest 108:537–546, 2001. at –7 kilobases. J Biol Chem 270:7167–7175, 1995.
89. Fukodome K, Esmon CT: Identification, cloning, and regulation of a novel endothelial 123. van Hinsbergh VW, Bauer KA, Kooistra T, et al: Progress of fibrinolysis during tumor
cell protein C/activated protein C receptor. J Biol Chem 269:26486–26491, 1994. necrosis factor infusions in humans. Concomitant increase in tissue-type plasminogen
90. Esmon CT, Gu J, Xu J, et al: Regulation and functions of the protein C anticoagulant activator, plasminogen activator inhibitor type-1, and fibrin(ogen) degradation prod-
pathway. Haematologica 84:363–368, 1999. ucts. Blood 76:2284–2289, 1990.
91. Esmon CT, Xu J, Gu J, et al: Endothelial protein C receptor. Thromb Haemost 82:251– 124. Hamsten A, Wiman B, De Faire U, Blomback M: Increased plasma levels of a rapid
258, 1999. inhibitor of tissue plasminogen activator in young survivors of myocardial infarction.
92. Esmon CT: The endothelial cell protein C receptor. Curr Opin Hematol 13:382–385, N Engl J Med 313:1557–1563, 1985.
2006. 125. Pizzo SV, Murray JC, Gonias SL: Atrophie blanche: A disorder associated with defective
93. Xu J, Liaw PC, Esmon CT: A novel transmembrane domain of the endothelial cell pro- release of tissue plasminogen activator. Arch Pathol Lab Med 110:517–519, 1986.
tein C receptor (EPCR) dictates receptor localization of sphingolipid-cholesterol rich 126. Kristensen P, Larson LI, Nielsen LS, et al: Human endothelial cells contain one type of
regions on plasma membrane while EPCR palmitoylation modulates intracellular traf- plasminogen activator. FEBS Lett 168:33–37, 1984.
ficking patterns. Thromb Haemost 1999. 127. Yamamoto K, Loskutoff DJ: Fibrin deposition in tissues from endotoxin-treated mice
94. Kurosawa S, Stearns-Kurosawa DJ, Hidari N, Esmon CT: Identification of functional correlates with decreases in the expression of urokinase-type but not tissue-type plas-
endothelial protein C receptor in human plasma. J Clin Invest 100:411–418, 1997. minogen activator. J Clin Invest 97:2440–2451, 1996.
95. Fukudome K, Ye X, Tsuneyoshi N, et al: Activation mechanism of anticoagulant protein 128. Bacharach E, Itin A, Keshet E: In vivo patterns of expression of urokinase and its inhib-
C in large blood vessels involving the endothelial cell protein C receptor. J Exp Med itor PAI-1 suggest a concerted role in regulating phsyiological angiogenesis. Proc Natl
187:1029–1035, 1998. Acad Sci U S A 89:10686–10690, 1992.
96. Taylor FB Jr, Peer GT, Lockhart MS: Endothelial cell protein C receptor plays an impor- 129. Booyse FM, Scheinbuks J, Radek J, et al: Immunological identification and compari-
tant role in protein C activation in vivo. Blood 97:1685–1688, 2001. sion of plasminogen activator forms in cultured normal human endothelial cells and
97. Esmon CT, Taylor FB, Snow TR: Inflammation and coagulation: Linked processes smooth muscle cells. Thromb Res 24:495–504, 1981.
potentially regulated through a common pathway mediated by protein C. Thromb 130. van Hinsbergh VW, van den Berg EA, Fiers W, Dooijewaard G: Tumor necrosis factor
Haemost 66:160–165, 1991. induces the production of urokinase-type plasminogen activator by human endothelial
98. Esmon CT, Schwarz HP: An update on clinical and basic aspects of the protein C anti- cells. Blood 75:1991–1998, 1990.
coagulant pathway. Trends Cardiovasc Med 5:141–148, 1995. 131. Sawdey M, Podor TJ, Loskutoff DJ: Regulation of type-1 plasminogen activator inhibi-
99. Ranieri VM, Thompson BT, Barie PS, et al: Drotrecogin alfa (activated) in adults with tor gene expression in cultured bovine aortic endothelial cells. J Biol Chem 264:10396–
septic shock. N Engl J Med 366:2055–2064, 2012. 10401, 1989.
100. Gu JM, Crawley JTB, Ferrell G, et al: Disruption of the endothelial cell protein C recep- 132. van den Berg EA, Sprengers ED, Jaye M, et al: Regulation of plasminogen activator
tor gene in mice causes placental thrombosis and early embryonic lethality. J Biol Chem inhibitor-1 mRNA in human endothelial cells. Thromb Haemost 60:63–67, 1988.
277:43335–43343, 2002. 133. Ellis V, Scully MF, Kakkar VV: Plasminogen activation by single-chain urokinase in
101. Weiler H, Isermann B: Thrombomodulin. J Thromb Haemost 1:1515–1524, 2003. functional isolation. J Biol Chem 262:14998–15003, 1987.
102. Todd AS: Fibrinolysis autographs. Nature 181:495–496, 1958. 134. Blasi F, Carmeliet P: uPAR: A versatile signalling orchestrator. Nat Rev Mol Cell Biol
103. Todd AS: Localization of fibrinolytic activity in tissues. Br Med Bull 20:210–212, 1964. 3:932–943, 2002.
104. Augustin HG, Kozian DH, Johnson RC: Differentiation of endothelial cells: Analysis of 135. Almus-Jacobs F, Varki N, Sawdey MS, Loskutoff DJ: Endotoxin stimulates expression of
the constitutive and activated endothelial cell phenotypes. Bioessays 16:901–906, 1994. the murine urokinase receptor gene in vivo. Am J Pathol 147:688–698, 1995.
105. van Hinsbergh VW, Kooistra T, Emeis JJ, Koolwijk P: Regulation of plasminogen activa- 136. Medina R, Socher SH, Han JH, Friedman PA: Interleukin-1, endotoxin, or tumor
tor production by endothelial cells: Role in fibrinolysis and local proteolysis. Int J Radiat necrosis factor/cachectin enhance the level of plasminogen activator inhibitor messen-
Biol 60:261–272, 1991. ger RNA in bovine aortic endothelial cells. Thromb Res 54:41–52, 1989.
106. Levin EG, del Zoppo GJ: Localization of tissue plasminogen activator in the endothe- 137. Etingin OR, Hajjar DP, Hajjar KA, et al: Lipoprotein(a) regulates plasminogen activator
lium of a limited number of vessels. Am J Pathol 144:855–861, 1994. inhibitor-1 expression in endothelial cells. J Biol Chem 266:2459–2465, 1990.
107. Levin EG, Santell L, Osborn KG: The expression of endothelial tissue plasminogen 138. Konkle B, Ginsburg D: The addition of endothelial cell growth factor and heparin to
activator in vivo: A function defined by vessel size and anatomic location. J Cell Sci human endothelial cell cultures decrease plasminogen activator. J Clin Invest 82:579, 1988.
110:139–148, 1997. 139. Greenberg ME, Brackenbury R, Edelman GM: Changes in the distribution of the
108. Levin EG, Osborn KG, Schleuning WD: Vessel-specific gene expression in the lung: 34-kdalton tyrosine kinase substrate during differentiation and maturation of chicken
Tissue plasmingen activator is limited to bronchial arteries and pulmonary vessels of tissues. J Cell Biol 98:473–486, 1984.
discrete size. Chest 114:68S, 1998. 140. Hamre KM, Chepenik KP, Goldowitz D: The annexins: Specific markers of midline
109. O’Rourke J, Jiang X, Hao Z, Cone RE, Hand AR: Distribution of sympathetic tissue structures and sensory neurons in the developing murine central nervous system. J
plasminogen activator (tPA) to a distant microvasculature. J Neurosci 79:727–733, 2005. Comp Neurol 352:421–435, 1995.
110. Dichek D, Quertermous T: Thrombin regulation of mRNA levels of tissue plasmino- 141. Gould KL, Cooper JA, Hunter T: The 46,000-dalton tyrosine kinase substrate is wide-
gen activator inhibitor-1 in cultured human umbilical vein endothelial cells. Blood 74: spread, whereas the 36,000-dalton substrate is only expressed at high levels in certain
222–228, 1989. rodent tissues. J Cell Biol 98:487–497, 1984.
111. Hanss M, Collen D: Secretion of tissue-type plasminogen activator and plasminogen 142. Dreier R, Schmid KW, Gerke V, Riehemann K: Differential expression of annexins
activator inhibitor by cultured human endothelial cells: Modulation by thrombin, I, II, and IV in human tissues: An immunohistochemical study. Histochem Cell Biol
endotoxin, and histamine. J Lab Clin Med 109:97–104, 1987. 110:137–148, 1998.
112. Levin EG, Santell L: Stimulation and desensitization of tissue plasminogen activator 143. Huang B, Deora AB, He K, et al: Hypoxia-inducible factor-1 drives annexin A2 system-
release from human endothelial cells. J Biol Chem 263:9360–9365, 1988. mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice. Blood
113. Shatos MA, Doherty JM, Orfeo T, et al: Modulation of the fibrinolytic response of cul- 118(10):2918–2929, 2011.
tured human vascular endothelium by extracellularly generated oxygen radicals. J Biol 144. Jacovina AT, Zhong F, Khazanova E, et al: Neuritogenesis and the nerve growth fac-
Chem 267:597–601, 1992. tor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin gener-
114. Levin EG, Marotti KR, Santell L: Protein kinase C and the stimulation of tissue plas- ation. J Biol Chem 276:49350–49358, 2001.
minogen activator release from human endothelial cells. J Biol Chem 264:16030–16036, 145. Brownstein C, Deora AB, Jacovina AT, et al: Annexin II mediates plasminogen-
1989. dependent matrix invasion by human monocytes: Enhanced expression by macro-
115. Cugno M, Uziel L, Fabrizi I, et al: Fibrinolytic response in normal subjects to venous phages. Blood 103:317–324, 2004.
oclusion and DDAVP infusion. Thromb Res 56:625–634, 1989. 146. Menell JS, Cesarman GM, Jacovina AT, et al: Annexin II and bleeding in acute promy-
116. Kooistra T, van den Berg J, Tons A, et al: Butyrate stimulates tissue type plasminogen elocytic leukemia. N Engl J Med 340:994–1004, 1999.
activator synthesis in cultured human endothelial cells. Biochem J 247:605–612, 1987. 147. Tallman MS, Abutalib SA, Altman JK: The double hazard of thrombophilia and bleed-
117. Diamond SL, Eskin SG, McIntire LV: Fluid flow stimulates tissue plasminogen activator ing in acute promyelocytic leukemia. Semin Thromb Hemost 33:330–338, 2007.
secretion by cultured human endothelial cells. Science 243:1483–1485, 1989. 148. Stein E, McMahon B, Kwaan H, et al: The coagulopathy of acute promyelocytic leu-
118. Diamond SL, Sharefkin JB, Dieffenbach C, et al: Tissue plasminogen activator messen- kaemia revisited. Best Pract Res Clin Haematol 22:152–163, 2009.
ger RNA levels increase in cultured human endothelial cells exposed to laminar shear 149. Liu Y, Wang Z, Jiang M, et al: The expression of annexin II and its role in the fibrinolytic
stress. J Cell Physiol 143:364–371, 1990. activity in acute promyelocytic leukemia. Leuk Res 35:879–884, 2011.
119. Levin EG, Santell L, Saljooque F: Hyperosmotic stress stimulates tissue plasminoeg 150. Ishii H, Yoshida M, Hiraoka M, et al: Recombinant annexin II modulates impaired
activator expression by a PKC-dependent pathway. Am J Physiol 265:C387–C396, 1993. fibrinolytic activity in vitro and in rat carotid artery. Circ Res 89:1240–1245, 2001.
120. Iba T, Shin T, Sonoda T, et al: Stimulation of endothelial secretion of tissue-type plas- 151. Ling Q, Jacovina AT, Deora AB, et al: Annexin II is a key regulator of fibrin homeostasis
minogen activator by repetitive stretch. J Surg Res 50:457–460, 1991. and neoangiogenesis. J Clin Invest 113:38–48, 2004.
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