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2318 Part XII: Hemostasis and Thrombosis Chapter 135: Fibrinolysis and Thrombolysis 2319

16. Hayes ML, Castellino FJ: Carbohydrate composition of the human plasminogen vari- 47. Feng P, Ohlsson M, Ny T: The structure of the TATA-less rat tissue-type plasminogen
ants. II. Structure of the asparagine-linked oligosaccharide unit. J Biol Chem 254:8772– activator gene. J Biol Chem 265:2022–2027, 1990.
8776, 1979. 48. Kooistra T, Bosma PJ, Toet K, et al: Role of protein kinase C and cyclic adenosine
17. Hayes ML, Castellino FJ: Carbohydrate of the human plasminogen variants. III. Struc- monophosphate in the regulation of tissue-type plasminogen activator, plasmino-
ture of the O-glycosidically-linked oligosaccharide unit. J Biol Chem 254:8777–8780, gen activator inhibitor-1, and platelet-derived growth factor mRNA levels in human
1979. endothelial cells. Possible involvement of proto-oncogenes c-jun and c-fos. Arterioscler
18. Saksela O: Plasminogen activation and regulation of proteolysis. Biochim Biophys Acta Thromb 11:1042–1052, 1991.
823:35–65, 1985. 49. Medcalf RL, Ruegg M, Schleuning WD: A DNA motif related to the cAMP-responsive
19. Wallen P, Wiman B: Characterization of human plasminogen. I. On the relationship element and an exon-located activator protein-2 binding site in the human tissue-type
between different molecular forms of plasminogen demonstrated in plasma and found plasminogen activator gene promoter cooperate in basal expression and convey activa-
in purified preparations. Biochim Biophys Acta 221:20–30, 1970. tion by phorbol ester and cAMP. J Biol Chem 265:14618–14626, 1990.
20. Wallen P, Wiman B: Characterization of human plasminogen. II. Separation and partial 50. Kooistra T, Van den Berg J, Tons A, et al: Butyrate stimulates tissue type plasminogen
characterization of different molecular forms of human plasminogen. Biochim Biophys activator synthesis in cultured human endothelial cells. Biochem J 247:605–612, 1987.
Acta 157:122–134, 1972. 51. Diamond SL, Eskin SG, McIntire LV: Fluid flow stimulates tissue plasminogen activator
21. Holvoet P, Lijnen HR, Collen D: A monoclonal antibody specific for lys-plasminogen. secretion by cultured human endothelial cells. Science 243:1483–1485, 1989.
J Biol Chem 260:12106–12111, 1985. 52. Hanss M, Collen D: Secretion of tissue-type plasminogen activator and plasminogen
22. Hoylaerts M, Rijken DC, Lijnen HR, Collen D: Kinetics of the activation of plasmino- activator inhibitor by cultured human endothelial cells: Modulation by thrombin,
gen by human tissue plasminogen activator: Role of fibrin. J Biol Chem 257:2912–2929, endotoxin, and histamine. J Lab Clin Med 109:97–104, 1987.
1982. 53. Thompson EA, Nelles L, Collen D: Effect of retinoic acid on the synthesis of tissue-type
23. Hajjar KA, Nachman RL: Endothelial cell-mediated conversion of glu-plasminogen to plasminogen activator and plasminogen activator inhibitor 1 in human endothelial
lys-plasminogen: Further evidence for assembly of the fibrinolytic system on the endo- cells. Eur J Biochem 201:627–632, 1991.
thelial cell surface. J Clin Invest 82:1769–1778, 1988. 54. Kooistra T, Opdenberg JP, Toet K, et al: Stimulation of tissue-type plasminogen acti-
24. Silverstein RL, Friedlander RJ, Nicholas RL, Nachman RL: Binding of lys-plasminogen vator synthesis by retinoids in cultured human endothelial cells and rat tissue in vivo.
to monocytes and macrophages. J Clin Invest 82:1948–1955, 1988. Thromb Haemost 65:565–572, 1991.
25. Murray JC, Buetow KH, Donovan M, et al: Linkage disequilibrium of plasminogen 55. Medcalf RL, Van den Berg E, Schleuning WD: Glucocorticoid-modulated gene expres-
polymorphisms and assignment of the gene to human chromosome 6q26–6q27. Am sion of tissue- and urinary-tyype plasminogen activator and plasminogen activator
J Hum Genet 40:338–350, 1987. inhibitor-1 and 2. J Cell Biol 106:971–978, 1988.
26. Petersen TE, Martzen MR, Ichinose A, Davie EW: Characterization of the gene 56. Santell L, Levin EG: Cyclic AMP potentiates phorbol ester stimulation of tissue plas-
for human plasminogen, a key proenzyme in the fibrinolytic system. J Biol Chem minogen activator release and inhibits secretion of plasminogen activator inhibitor-1
265:6104–6111, 1990. from human endothelial cells. J Biol Chem 263:16802–16808, 1988.
27. Jenkins GR, Seiffert D, Parmer RJ, Miles LA: Regulation of plasminogen gene expres- 57. Levin EG, del Zoppo GJ: Localization of tissue plasminogen activator in the endothe-
sion by interleukin-6. Blood 89:2394–2403, 1997. lium of a limited number of vessels. Am J Pathol 144:855–861, 1994.
28. McLean JW, Tomlinson JE, Kuang WJ, et al: cDNA sequence of human apolipopro- 58. Levin EG, Santell L, Osborn KG: The expression of endothelial tissue plasminogen
tein(a) is homologous to plasminogen. Nature 330:132–137, 1987. activator in vivo: A function defined by vessel size and anatomic location. J Cell Sci
29. Nakamura T, Nishizawa T, Hagiya M, et al: Molecular cloning and expression of human 110:139–148, 1997.
hepatocyte growth factor. Nature 342:440–443, 1989. 59. Levin EG, Osborn KG, Schleuning WD: Vessel-specific gene expression in the lung:
30. Weissbach L, Treadwell BV: A plasminogen-related gene is expressed in cancer cells. Tissue plasmingen activator is limited to bronchial arteries and pulmonary vessels of
Biochem Biophys Res Commun 186:1108–1114, 1992. discrete size. Chest 114:68S, 1998.
31. Yoshimura T, Yuhki N, Wang MH, et al: Cloning, sequencing, and expression of human 60. Diamond SL, Sharefkin JB, Dieffenbach C, et al: Tissue plasminogen activator messen-
macrophage stimulating protein (MSP, MST 1) confirms MSP as a member of the ger RNA levels increase in cultured human endothelial cells exposed to laminar shear
family of kringle proteins and locates the MSP gene on chromosome 3. J Biol Chem stress. J Cell Physiol 143:364–371, 1990.
268:15461–15468, 1993. 61. O’Rourke J, Jiang X, Hao Z, et al: Distribution of sympathetic tissue plasminogen acti-
32. Byrne CD, Schwartz K, Meer K, et al: The human apolipoprotein(a)/plasminogen gene clus- vator (tPA) to a distant microvasculature. J Neurosci 79:727–733, 2005.
ter contains a novel homologue transcribed in liver. Arterioscler Thromb 14:534–541, 1994. 62. Dichek D, Quertermous T: Thrombin regulation of mRNA levels of tissue plasminogen
33. Ichinose A: Multiple members of the plasminogen-apolipoprotein(a) gene family asso- activator inhibitor-1 in cultured human umbilical vein endothelial cells. Blood 74:222–
ciated with thrombosis. Biochemistry 31:3113–3118, 1992. 228, 1989.
34. Shanmukhappa K, Matte U, Degen JL, Bezerra JA: Plasmin-mediated proteolysis 63. Levin EG, Marotti KR, Santell L: Protein kinase C and the stimulation of tissue plasmino-
is required for hepatocyte growth factor activation during liver repair. J Biol Chem gen activator release from human endothelial cells. J Biol Chem 264:16030–16036, 1989.
284:12917–12923, 2009. 64. Kasai S, Arimura H, Nishida M, Suyama T: Primary structure of single-chain pro-
35. Bugge TH, Flick MJ, Daugherty CC, Degen JL: Plasminogen deficiency causes severe urokinase. J Biol Chem 260:12382–12389, 1985.
thrombosis but is compatible with development and reproduction. Genes Dev 9: 65. Gunzler WA, Steffens GJ, Otting F, et al: Structural relationship between high and low
794–807, 1995. molecular mass urokinase. Hoppe Seylers Z Physiol Chem 363:133–141, 1982.
36. Ploplis VA, Carmeliet P, Vazirzadeh S, et al: Effects of disruption of the plasminogen 66. Riccio A, Grimaldi G, Verde P, Sebastio G, Boast S, Blasi F: The human urokinase-
gene on thrombosis, growth, and health in mice. Circulation 92:2585–2593, 1995. plasminogen activator gene and its promoter. Nucleic Acids Res 13:2759–2771, 1985.
37. Drew AF, Kaufman AH, Kombrinck KW, et al: Ligneous conjunctivitis in plasminogen- 67. Holmes WE, Pennica D, Blaber M, et al: Cloning and expression of the gene for
deficient mice. Blood 91:1616–1624, 1998. pro-urokinase in Escherichia coli. Nat Biotechnol 3:923, 1985.
38. Pennica D, Holmes WE, Kohr WJ, et al: Cloning and expression of human tissue-type 68. Schmitt M, Wilhelm O, Janicke F, et al: Urokinase-type plasminogen activator (uPA)
plasminogen activator cDNA in E. coli. Nature 301:214–221, 1983. and its receptor (CD87): A new target in tumor invasion and metastasis. J Obstet
39. Tate KM, Higgins DL, Holmes WE, et al: Functional role of proteolytic cleavage at Gynaecol 21:151–165, 1995.
arginine-275 of human tissue plasminogen activator as assessed by site-directed muta- 69. Van Hinsbergh VW, Kooistra T, Van den Berg EA, et al: Tumor necrosis factor increases
genesis. Biochemistry 26:338–343, 1987. the production of plasminogen activator inhibitor in human endothelial cells in vitro
40. Pohl G, Kenne L, Nilsson B, Einarsson M: Isolation and characterization of three dif- and in rats in vivo. Blood 72:1467–1473, 1988.
ferent carbohydrate chains from melanoma tissue plasminogen activator. Eur J Biochem 70. Medina R, Socher SH, Han JH, Friedman PA: Interleukin-1, endotoxin, or tumor
170:69–75, 1987. necrosis factor/cachectin enhance the level of plasminogen activator inhibitor messen-
41. Spellman MW, Basa LJ, Leonard CK, Chakel JA: Carbohydrate structures of tissue plas- ger RNA in bovine aortic endothelial cells. Thromb Res 54:41–52, 1989.
minogen activator expressed in Chinese hamster ovary cells. J Biol Chem 264:14100– 71. Gerwin BI, Keski-Oja J, Seddon M, et al: TGF beta 1 modulation of urokinase and
14111, 1989. PAI-1 expression in human bronchial epithelial cells. Am J Pathol 259:262–269, 1990.
42. Harris RJ, Leonard CK, Guzzetta AW: Tissue plasminogen activator has an O-linked 72. Stump DC, Lijnen HR, Collen D: Purification and characterization of a novel low
fucose attached to threonine-61 in the epidermal growth factor domain. Biochemistry molecular weight form of single-chain urokinase-type plasminogen activator. J Biol
30:2311–2314, 1991. Chem 261:17120–17126, 1986.
43. Ny T, Elgh F, Lund B: Structure of the human tissue-type plasminogen activator gene: 73. Steffens GJ, Gunzler WA, Olting F, et al: The complete amino acid sequence of low
Correlation of intron and exon structures to functional and structural domains. Proc molecular mass urokinase from human urine. Hoppe Seylers Z Physiol Chem 363:1043–
Natl Acad Sci U S A 81:5355–5359, 1984. 1058, 1982.
44. Browne MJ, Tyrrell AWR, Chapman CG, et al: Isolation of a human tissue-type plasmino- 74. Lijnen HR, Zamarron C, Blaber M, et al: Activation of plasminogen by prourokinase: I.
gen activator genomic clone and its expression in mouse L cells. Gene 33:279–284, 1985. Mechanism. J Biol Chem 261:1253–1258, 1986.
45. Degen SJF, Rajput B, Reich E: The human tissue plasminogen activator gene. J Biol 75. Gurewich V, Pannell R, Louie S, et al: Effective and fibrin-specific clot lysis by a zymogen
Chem 261:6872–6885, 1986. precursor from urokinase (pro-urokinase). A study in vitro and in two animal species.
46. Van Zonnefeld AJ, Veerman H, Pannekoek H: Autonomous functions of structural J Clin Invest 73:1731–1739, 1984.
domains on human tissue-type plasminogen activator. Proc Natl Acad Sci U S A 76. Colman RW: Activation of plasminogen by human plasma kallikrein. Biochem Biophys
83:4670–4674, 1986. Res Commun 35:273–279, 1968.

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