Page 2433 - Williams Hematology ( PDFDrive )

2404 Index Index 2405

Autosomal recessive agammaglobulinemia, empiric therapy, 384–385, 387t in chronic myelogenous leukemia, 1445
1212–1213, 1214t in febrile nonhemolytic transfusion development, 926f
Autosomal recessive hyper-IgE syndrome. reaction, 2375 distinguishing features, 966, 966f
See Hyperimmunoglobulin E after hematopoietic cell transplantation, heterogeneity, 966–967
syndrome (HIES) 369 mast cells and, 967–968
Autosomal recessive hyper-IgM syndrome. in immunocompromised host, 383 mediators, 967t, 968
See Hyperimmunoglobulin M from platelet products, 2386, 2388 natural history, 967t
syndromes prevention, 388–389 in newborn, 105t
Autosomal recessive inheritance, 149, 149f purpura and, 2104, 2104f reference ranges, 15t, 970
Autosomal recessive megaloblastic anemia TLR-signaling defects with increased role in IgE-associated immune response,
(MGA1), 605 susceptibility to, 1230 968–969
Avascular necrosis, 771, 771f Bacterial permeability-increasing protein structure, 20f, 23, 929f, 930–931, 930f,
Avatrombopag, for immune (BPI), 106–107, 1011, 1012t, 1013 931f, 968
thrombocytopenia, 526 Bactericidal activity, in newborn, 106–107 surface membrane structures, 967t
5-Azacytidine, 322 Baculovirus inhibitor of apoptosis repeat Bassen-Kornzweig syndrome
for acute myelogenous leukemia, 1403 (BIR) domains, 207, 298 (abetalipoproteinemia), 670f, 681
for chronic myelomonocytic leukemia, 1469 BAF (BRG/BAF-associated factors) complex, Bax, 204f, 206
mechanism of action, 239, 1360 166, 166f BAX, 951
for myelodysplastic syndromes, 336, 1360, BAFF (B-cell activation factor), 309, BAX, 210
1361 1713 B-cell activation factor (BAFF), 309, 1713
for sickle cell disease, 774t, 775 Bak, 204f, 206 B-cell acute lymphoblastic leukemia (B-ALL).
5-Aza-2′-deoxycytidine. See Decitabine BAK, 1528 See also Acute lymphoblastic
6-Azantidine, megaloblastic anemia and, 606t B-ALL. See B-cell acute lymphoblastic (lymphocytic) leukemia (ALL)
Azathioprine, 322 leukemia (B-ALL) chromosomal abnormalities, 186f,
for autoimmune hemolytic anemia, 839 Band 3, 664, 664f, 670t, 672 221–222t, 1494t
for immune thrombocytopenia, 2006–2007 Band 3 clustering models, 498 vs. chronic lymphocytic leukemia, 1543
megaloblastic anemia and, 606t Band cells, marrow, 34 differential diagnosis, 1674
for pure red cell aplasia, 544 Banded chromosome, 175t gene mutations, 232–233t, 1494t
Azidothymidine, anemia induced by, 561 Band form, marrow, 32t immunologic subtypes, 1512t
Azithromycin, for babesiosis, 819 Band neutrophils laboratory features, 1511, 1511f, 1512t
AZT. See Zidovudine (AZT) development, 926f, 939 Philadelphia chromosome-like, 177f, 186,
Aztreonam, 387t kinetics, 941t 232–233t
Azurocidin (heparin-binding protein), 1012t, structure, 20f, 926–927, 927f precursor (immature), 183, 184t, 186f,
1013 Bands, 22 1515–1517, 1521t
Azurophil granules Baroreflex, 91 prognosis, 1520
in acute myeloblastic leukemia, 1387 Barr bodies, 150, 150f therapy, 1514, 1515
formation, 1009, 1010f Bartonella infection (bartonellosis, Oroya B-cell antigen-receptor vaccines, 423
heterogeneity, 1009 fever), 818, 997 B-cell antigens, 1141, 1141f
laboratory features, 926, 928f Bartter syndrome, 2086 B-cell linker protein (BLNK), 1144, 1163
physical-chemical and functional Basal coagulation, 1942 B-cell lymphoblastic lymphoma. See B-cell
properties, 1011–1013, 1012t Basket cells, 23 acute lymphoblastic leukemia
Basophilia, 971–972 (B-ALL)
B in clonal myeloid diseases, 971–972, 972t B-cell maturation antigen (BCMA), 1606
B-1 B cells, 1141, 1151 consultative approach to, 44 B-cell neoplasms. See also specific types
B-2 B cells, 1151 in inflammatory and immunologic development stages, 1591f
B19 parvovirus infection. See Parvovirus B19 responses, 971 immature/precursor, 1494t, 1592
infection punctate, 468 leukemias, 1494t
BA2. See CD9 Basophilic erythroblasts, 34, 463f, 464, 464f lymphomas
Babesia, 819–820 Basophilic leukemia, 971–972, 972t chromosomal abnormalities, 184t, 186f,
Babesiosis, 429t, 432, 817f, 818–819 Basophilic megaloblasts, 595f 1494–1497t
Bacillus cereus, 809 Basophilic stippling, 467f, 468 chronic lymphocytic leukemia and, 1542
Back disorders, history of, 6 Basophilopenia, 971 classification, 1493, 1494–1497t
Bacterial infections. See also specific bacteria Basophils clinical features, 1501–1502
antiphospholipid antibodies and, 2234 alterations in numbers, 970–972, 971t, extranodal involvement, 1502
disseminated intravascular coagulation 972t B-cell precursor acute lymphoblastic
and, 2207 biologic functions, 969–970 leukemia, 1512t

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