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 2406  Index                                                                                            Index         2407



                  Blind loop syndrome, 601, 604         in alloimmune hemolytic disease of the   B-lymphocyte-induced maturation protein-1
                  BLM, 1227                                  fetus and newborn, 856f              (Blimp-1), 1171–1172, 1710, 1710f
                  BLNK (B-cell linker protein), 1144, 1163  in autoimmune hemolytic anemia, 833f  B lymphocytes. See B cells
                  BLOCs (biogenesis of lysosome-related   in babesiosis, 817f              BMP. See Bone morphogenetic protein
                         organelles complexes), 1843, 2053,   in β-thalassemia, 746f              (BMP)
                         2053f                          in chronic lymphocytic leukemia,    Bohr effect, 504
                  Blood                                      1530–1531, 1530f              Bolzano effect, 2049
                    basophil count, 970                 in chronic myelogenous leukemia,    Bombay (Oh) phenotype, 2341t, 2343
                    control of fluidity of, 2285             1445–1446, 1446f              Bone
                    dendritic cell count, 1098          in C. perfringens septicemia, 817f  giant cell tumor, 1110
                    eosinophil count, 953–954           in Epstein-Barr virus mononucleosis,   infarction, 771
                    examination, 11–23. See also specific blood   1264f                     primary lymphomas in, 1583
                         cells                          in erythrocyte membrane disorders, 670f  Bone cells, marrow, 59–60
                     automated analyses, 11–12, 12f, 13f  in hemoglobin H disease, 747f    Bone lesions/pain
                     morphological, 20, 20f, 21f, 22f   in hemolytic anemia, 810f           in acute myelogenous leukemia, 1381,
                     reference ranges/normal values, 14t,   in hereditary elliptocytosis, 670f, 679  1385
                         18–19, 18t, 19f                in hereditary pyropoikilocytosis, 677f,    in Gaucher disease, 1124, 1125f, 1127
                    heterogeneity of monocytes in, 1079f     679                            in hairy cell leukemia, 1555
                    neutrophil kinetics, 941–942, 942t  in hereditary spherocytosis, 670f, 675  history of, 6
                    as source of hematopoietic stem cells for   in hereditary stomatocytosis, 670f  in Langerhans cell histiocytosis, 1104,
                         transplantation, 355–356       in iron deficiency, 633f                  1105, 1105f, 1106
                    umbilical cord, 357                 lymphocytes, 1138f                  in myeloma, 1713, 1737–1738, 1738f, 1745,
                    viscosity of                        in malaria, 817f                          1756
                     hematocrit and, 506, 508f          monocytes, 1047f                    in primary myelofibrosis, 1325, 1325t
                     in newborns, 103–104               in mycosis fungoides, 1683, 1683f  Bone morphogenetic protein (BMP)
                  Blood banking system (blood procurement/  in myelodysplastic syndromes, 1350f  in early stem cell development, 54
                         screening), 2365–2369          in myeloma, 1743f                   in fibroplasia, 1322
                    autologous donor blood, 2367–2368   in pernicious anemia, 594f         Bone morphogenetic protein (BMP)-4
                    blood containers, 2367              in persistent polyclonal lymphocytosis of B   upregulation, 54
                    collection by apheresis, 2368–2369       lymphocytes, 1201f            Bone morphogenetic protein (BMP)-6, in
                    directed donor blood, 2368          plasma cells, 1138f                       iron homeostasis, 621t
                    donor recruitment, 2366             postsplenectomy, 869f              Bone morphogenetic protein (BMP) receptor
                    donor screening, 2366–2367          in primary myelofibrosis, 1323f           subunit, 42., 621t
                    international practices, 2365–2366  in sickle cell disease, 775f, 779f  Bone morphogenetic protein (BMP)
                    laboratory testing in, 2349, 2369, 2369t  in structural hemoglobinopathies, 779f  subfamilies, 249
                    patient-specific donation, 2368     in thalassemia intermedia, 746f    Borderline lesions, in cutaneous T-cell
                    procurement of plasma derivatives, 2366  in Waldenström macroglobulinemia,    lymphoma, 1688
                    safety of, 2369, 2369t, 2370t            1786f, 1791                   Bordetella pertussis infections, 1137, 1138f,
                    storage times, 2377               Blood group systems, 2329–2336, 2330t,      1139, 1202
                    therapeutic bleeding, 2368               2331–2333t. See also Erythrocyte   Borrelia burgdorferi, 1574, 1664, 2104, 2311
                    U.S. system, 2365, 2366t                 antibodies; Erythrocyte antigens;   Bortezomib, 342–343, 342f
                    venipuncture and blood collection, 2367  specific blood groups          for acute myelogenous leukemia, 1396,
                  Blood blisters, 1987                  definitions and history, 2329             1403
                  Blood count                           disease and, 2340                   adverse effects, 343, 1740, 1746, 1757, 1794
                    in essential thrombocythemia, 1310  genetics, 2339                      for AL amyloidosis, 1761, 1781
                    in Gaucher disease, 1125            immune antibodies and, 2347–2348    for autoimmune hemolytic anemia, 839
                    in primary myelofibrosis, 1325–1326  naturally occurring antibodies and,    for gastric MALT lymphoma, 1666t
                  Blood cysts (pseudotumors), 2119, 2120f    2347                           for mantle cell lymphoma, 1657t, 1658,
                  Blood dendritic cells, 1092, 1098     serologic detection, 2348–2350            1659t, 1660t
                  Blood donation, iron deficiency and, 629–630  Blood islands, 257          mechanism of action, 241, 1193
                  Blood films/findings, 20–23, 22f    Blood loss. See Bleeding              for myelodysplastic syndromes, 1360
                    in acute infection lymphocytosis, 1203f  Blood volume                   for myeloma, 1750, 1751, 1752, 1752t,
                    in acute lymphoblastic leukemia, 1511,   in pregnancy, 119                    1753t, 1754
                         1511f                          regulation, 91                      for primary effusion lymphoma, 1247
                    in acute myelogenous leukemia, 1381,   Bloom syndrome, 1227, 1507, 1575t  for Waldenström macroglobulinemia,
                         1382f                        Blue toe syndrome, 2298                     1794, 1795








          Kaushansky_index_p2393-2506.indd   2407                                                                       9/21/15   3:21 PM
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