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2406 Index Index 2407
Blind loop syndrome, 601, 604 in alloimmune hemolytic disease of the B-lymphocyte-induced maturation protein-1
BLM, 1227 fetus and newborn, 856f (Blimp-1), 1171–1172, 1710, 1710f
BLNK (B-cell linker protein), 1144, 1163 in autoimmune hemolytic anemia, 833f B lymphocytes. See B cells
BLOCs (biogenesis of lysosome-related in babesiosis, 817f BMP. See Bone morphogenetic protein
organelles complexes), 1843, 2053, in β-thalassemia, 746f (BMP)
2053f in chronic lymphocytic leukemia, Bohr effect, 504
Blood 1530–1531, 1530f Bolzano effect, 2049
basophil count, 970 in chronic myelogenous leukemia, Bombay (Oh) phenotype, 2341t, 2343
control of fluidity of, 2285 1445–1446, 1446f Bone
dendritic cell count, 1098 in C. perfringens septicemia, 817f giant cell tumor, 1110
eosinophil count, 953–954 in Epstein-Barr virus mononucleosis, infarction, 771
examination, 11–23. See also specific blood 1264f primary lymphomas in, 1583
cells in erythrocyte membrane disorders, 670f Bone cells, marrow, 59–60
automated analyses, 11–12, 12f, 13f in hemoglobin H disease, 747f Bone lesions/pain
morphological, 20, 20f, 21f, 22f in hemolytic anemia, 810f in acute myelogenous leukemia, 1381,
reference ranges/normal values, 14t, in hereditary elliptocytosis, 670f, 679 1385
18–19, 18t, 19f in hereditary pyropoikilocytosis, 677f, in Gaucher disease, 1124, 1125f, 1127
heterogeneity of monocytes in, 1079f 679 in hairy cell leukemia, 1555
neutrophil kinetics, 941–942, 942t in hereditary spherocytosis, 670f, 675 history of, 6
as source of hematopoietic stem cells for in hereditary stomatocytosis, 670f in Langerhans cell histiocytosis, 1104,
transplantation, 355–356 in iron deficiency, 633f 1105, 1105f, 1106
umbilical cord, 357 lymphocytes, 1138f in myeloma, 1713, 1737–1738, 1738f, 1745,
viscosity of in malaria, 817f 1756
hematocrit and, 506, 508f monocytes, 1047f in primary myelofibrosis, 1325, 1325t
in newborns, 103–104 in mycosis fungoides, 1683, 1683f Bone morphogenetic protein (BMP)
Blood banking system (blood procurement/ in myelodysplastic syndromes, 1350f in early stem cell development, 54
screening), 2365–2369 in myeloma, 1743f in fibroplasia, 1322
autologous donor blood, 2367–2368 in pernicious anemia, 594f Bone morphogenetic protein (BMP)-4
blood containers, 2367 in persistent polyclonal lymphocytosis of B upregulation, 54
collection by apheresis, 2368–2369 lymphocytes, 1201f Bone morphogenetic protein (BMP)-6, in
directed donor blood, 2368 plasma cells, 1138f iron homeostasis, 621t
donor recruitment, 2366 postsplenectomy, 869f Bone morphogenetic protein (BMP) receptor
donor screening, 2366–2367 in primary myelofibrosis, 1323f subunit, 42., 621t
international practices, 2365–2366 in sickle cell disease, 775f, 779f Bone morphogenetic protein (BMP)
laboratory testing in, 2349, 2369, 2369t in structural hemoglobinopathies, 779f subfamilies, 249
patient-specific donation, 2368 in thalassemia intermedia, 746f Borderline lesions, in cutaneous T-cell
procurement of plasma derivatives, 2366 in Waldenström macroglobulinemia, lymphoma, 1688
safety of, 2369, 2369t, 2370t 1786f, 1791 Bordetella pertussis infections, 1137, 1138f,
storage times, 2377 Blood group systems, 2329–2336, 2330t, 1139, 1202
therapeutic bleeding, 2368 2331–2333t. See also Erythrocyte Borrelia burgdorferi, 1574, 1664, 2104, 2311
U.S. system, 2365, 2366t antibodies; Erythrocyte antigens; Bortezomib, 342–343, 342f
venipuncture and blood collection, 2367 specific blood groups for acute myelogenous leukemia, 1396,
Blood blisters, 1987 definitions and history, 2329 1403
Blood count disease and, 2340 adverse effects, 343, 1740, 1746, 1757, 1794
in essential thrombocythemia, 1310 genetics, 2339 for AL amyloidosis, 1761, 1781
in Gaucher disease, 1125 immune antibodies and, 2347–2348 for autoimmune hemolytic anemia, 839
in primary myelofibrosis, 1325–1326 naturally occurring antibodies and, for gastric MALT lymphoma, 1666t
Blood cysts (pseudotumors), 2119, 2120f 2347 for mantle cell lymphoma, 1657t, 1658,
Blood dendritic cells, 1092, 1098 serologic detection, 2348–2350 1659t, 1660t
Blood donation, iron deficiency and, 629–630 Blood islands, 257 mechanism of action, 241, 1193
Blood films/findings, 20–23, 22f Blood loss. See Bleeding for myelodysplastic syndromes, 1360
in acute infection lymphocytosis, 1203f Blood volume for myeloma, 1750, 1751, 1752, 1752t,
in acute lymphoblastic leukemia, 1511, in pregnancy, 119 1753t, 1754
1511f regulation, 91 for primary effusion lymphoma, 1247
in acute myelogenous leukemia, 1381, Bloom syndrome, 1227, 1507, 1575t for Waldenström macroglobulinemia,
1382f Blue toe syndrome, 2298 1794, 1795
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