Page 2466 - Williams Hematology ( PDFDrive )

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2436 Index Index 2437

for paroxysmal nocturnal hemoglobinuria, Glutathione peroxidase, 692t, β Glycoprotein (GP)I (apolipoprotein H),
2
578 701t 2234, 2235, 2235f, 2236f, 2237
for thrombocytopenia in pregnancy, Glutathione reductase (GR), 692t, 698 Glycoprotein (GP)Ia/IIa. See Integrin α β
2 1
2010–2011 Glutathione reductase (GR) deficiency, 698, Glycoprotein (GP)Ib, 1830–1831f, 1841,
for thrombotic thrombocytopenic 700t, 701t, 705, 1020t, 1033 1865, 1866f, 1867f, 1868
purpura, 2256 Glutathione S transferase, 701t Glycoprotein (GP)Ibα (CD42b,c), 1833, 1837,
in thymic development, 85 Glutathione synthetase (GS), 692t, 698 1865–1868, 1866f, 1867f, 1877. See
for Waldenström macroglobulinemia, 1793 Glutathione synthetase (GS) deficiency, 700t, also Platelet-type (pseudo-) von
Glucose metabolism 705, 709, 1020t, 1033 Willebrand disease
enzymes, 692t, 694–697 Glutathione-5-transferase, 692t Glycoprotein (GP)Ibβ, 1866–1867
pathways, 192–193, 193f, 692–694, 693f Glutethimide, megaloblastic anemia and, Glycoprotein (GP)Ib/IX complex,
Glucose-6-phosphate, 192, 694 606t 1815–1816, 1831, 1834, 1866f,
Glucose-6-phosphate dehydrogenase (G6PD) GLUTs, 192 1867f, 1877
in chronic myelogenous leukemia, 1470 Glycation, aging and, 130–131 Glycoprotein (GP)Ib/IX/V complex (CD42),
erythrocyte aging and, 497 Glyceraldehyde-3-phosphate, 694, 695 1839, 1865–1868, 1866f, 1867f,
gene for, 697, 702 Glyceraldehyde-3-phosphate dehydrogenase, 1875f, 1881. See also Bernard-
in glucose metabolism, 696–697 701t Soulier syndrome
structure, 696–697, 697f Glyceraldehyde phosphate dehydrogenase, Glycoprotein (GP)Ic/IIa. See Integrin α β
6 1
variants, 702, 703t 692t, 695 Glycoprotein (GP)Ic*/IIa. See Integrin α β
5 1
Glucose-6-phosphate dehydrogenase (G6PD) Glycine C-succinyl transferase, 892 Glycoprotein (GP)IIb/IIIa. See Integrin α β
IIb 3
deficiency Glycine N-methyl transferase, 588 Glycoprotein (GP)IIb/IIIa antagonists. See
clinical features, 700t, 1020t Glycocalicin, 1866 Integrin α β antagonists
IIb 3
common forms for, 708–709 Glycocalix, 1834 Glycoprotein (GP)IV (CD36, FAT, SCARB3),
course and prognosis, 712 Glycogen storage diseases, 994 1872
definition and history, 689–690 Glycogen storage disease type 1b, 1026 deficiency, 2359
differential diagnosis, 711 Glycolipids, erythrocyte membrane, 662 in dense bodies, 1843
epidemiology, 690, 691f Glycolipid storage diseases. See Lipid storage in fatty acid transport, 1872
favism in, 692, 707, 709 diseases in monocytes and macrophages, 1052f,
genetics, 702 Glycolysis, 192–193, 193f, 199 1055, 1057t
hemolysis/hemolytic anemia in, 707, 708, in neutrophils, 932, 933t in platelet adhesion, 1833, 1872
708t in platelets, 1839–1840 in platelet-leukocyte interactions, 1856
laboratory features, 700t, 710–711 Glycolytic (Embden-Meyerhof) pathway, in platelet membrane, 1836
malaria resistance and, 690 692–694, 693f, 932, 933t thrombosis and, 1856
neonatal icterus/jaundice in, 709 Glycophorin A, 2337, 2338f thrombospondin and, 1845, 1879
platelet abnormalities in, 2061 Glycophorin B, 2338f Glycoprotein (GP)IV (CD36, FAT, SCARB3)
sickle cell disease severity and, 690 Glycophorin C, 668, 670t deficiency, 2051
therapy, 711 Glycophorins, 663t, 664–665 Glycoprotein (GP)V, 1816, 1868, 1881
Glucose phosphate isomerase (GPI) Glycoprotein (GP) Glycoprotein (GP)VI, 1833, 1851, 1857, 1869,
activity, 192, 692t lymphocyte function-associated, 1879–1880, 1880f, 2293
deficiency, 694, 700t, 704 1184–1185, 1185f Glycoprotein (GP)VI deficiency, 2052
in glucose metabolism, 694 in neutrophils, 2358 Glycoprotein (GP)IX (CD42a), 1865, 1866,
GLUT1 (SLC2A1), 192 in newborn, 108 1866f, 1867f
GLUT-3, 1836 in platelet membrane, 1838f, 1846–1847t, Glycoprotein (GP)27. See CD151
Glutamate carboxypeptidase II (folate 1857–1874, 1858–1859t. See also Glycosaminoglycans (GAGs), 69, 1936,
hydrolase), 586–587 specific proteins 1936f, 2027f, 2028
Glutamate cysteine ligase (GCL) deficiency, glycosyl phosphatidylinositol-anchored Glycosphingolipids, 1956
705 proteins, 571, 1871 Glycosylation
Glutamate cysteine synthetase, 698 immunoglobulin family of cell surface abnormalities, in congenital
Glutamate oxaloacetate transaminase (GOT), adhesion receptors, 1868–1870 dyserythropoietic anemia type II,
193 integrins. See Integrins 567
Glutamine, 192–193, 193f, 199 lectin-containing receptors, 1870–1871 in biosynthesis of von Willebrand factor,
γ-Glutamylcysteine synthetase, 688, 692t leucine-rich repeat glycoprotein 2166
γ-D-Glutamyl diaminopimelic acid (DAP), receptors, 1865–1868 in biosynthesis of VWF, 2167f
299, 301f scavenger receptors, 1871 Glycosyl phosphatidylinositol-anchored
Glutathione (GSH), 694, 698, 706–707 tetraspanins, 1871 proteins (GPI-APs), 571,
Glutathione disulfide (GSSG), 698 tyrosine kinase receptors, 1871–1872 1871

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