Page 2468 - Williams Hematology ( PDFDrive )

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2438 Index Index 2439

Günther disease. See Congenital Hallervorden-Spatz syndrome. See history of, 4–5
erythropoietic porphyria Pantothenate kinase-associated iron deficiency and, 632
Gut-associated lymphoid tissue (GALT), neurodegeneration (PKAN) Health history, 3–7, 4t
93–94, 94f Hallucinations, olfactory, 5 Heart disease. See Cardiovascular disease
Gut microbiome, 2287 HAMP (hepcidin) mutations, 642 Heart valve hemolysis, 804–806, 805f, 805t
GVD regimen, for Hodgkin lymphoma, Ham test, 571, 576 Heat-shock protein 70 peptide vaccine, 423
1616 Hand-foot syndrome, 771 Heat-shock protein inhibitors, 1403
GVHD. See Graft-versus-host disease Hand-Schüller-Christian disease. See Heat-shock proteins, 2288
(GVHD) Langerhans cell histiocytosis Heat stroke, disseminated intravascular
GVL (graft-versus-leukemia) effect, 307, 310, Hantavirus, 2104 coagulation and, 2209
1400, 1461 H antigen, 2330 Heavy-chain diseases (HCDs), 1803–1810,
GWAS (genome-wide association studies), Haploid, 175t 1804t
162 Hapten-drug absorption, 825f, 826t, 829–830, α-heavy-chain disease, 1806–1808, 1807f
GX15–070 (obatoclax), 1403 830t γ-heavy-chain disease, 1803–1806, 1805f
GYPA/B/C, 2339, 2342–2343 Haptocorrin deficiency, 607 μ-heavy-chain disease, 1809–1810, 1810f
Haptocorrins, 583, 591t, 592–593, 593t, 1448 Heavy chains, immunoglobulin, 1159–1163
H Haptoglobin, 293, 499, 500f allotypes, 1170
H3K27me3, 170 HARP (hypobetalipoproteinemia, class switching, 1168–1169
5H9. See CD9 acanthocytosis, retinitis gene complexes, 1165f, 1167f
H60, 515 pigmentosa and pallidal Hef2, 1444
Haemophilus influenzae degeneration) syndrome, 682 Heinz bodies
hemolytic anemia and, 819 HAS-BLED score, 396, 396t characteristics, 467f, 468
in hyperimmunoglobulin E syndrome, Hashimoto thyroiditis, lymphomas and, in G6PD deficiency, 710, 711
1026 1575, 1583, 1664 in hemoglobin H disease, 747, 747f
hyposplenism and, 868 Hassall corpuscles, 85, 86f hemolytic anemia with, 810
inflammation and, 290 HAT (hepatic artery thrombosis), 2195 in hyposplenism, 869
red cell antigens and, 2340 HAT (histone acetyltransferase) enzymes, Helicobacter pylori
vaccination, 869 167f, 168 in extranodal margin zone lymphoma of
X-linked recessive agammaglobulinemia HATs (histone acetylases), 240 MALT type, 1595, 1664, 1665
and, 1212 HAX1, 983, 993 immune thrombocytopenia and, 2009–
Hageman factor. See Factor XII Hb. See Hemoglobin (Hb) 2010
Hair loss, iron deficiency and, 632 H blood group, 2332t, 2333t iron-deficiency anemia and, 629, 630
Hairy cell leukemia (HCL), 1553–1559 HBV (hepatitis B virus) infection, 1574, 2126 lymphomas and, 1573, 1581
chromosomal abnormalities, 1494t HCAM (lymphocyte homing cell adhesion mastocytosis and, 976
clinical features, 1554–1555, 2082 molecule), 68 pernicious anemia and, 596
course and prognosis, 1559 hCAP-18 (LL-37, CAMP), 1012t, 1013 T-cell response to, 1180
definition and history, 1553–1554 HCDs. See Heavy-chain diseases (HCDs) HELLP syndrome, 801–802
differential diagnosis, 42, 1327, 1543, 1555, HCL. See Hairy cell leukemia (HCL) clinical features, 802
1557, 1558t HCP (hematopoietic cell phosphatase), 253, course and prognosis, 803
epidemiology, 1554 485, 486f, 1163 differential diagnosis, 802, 2012
etiology and pathogenesis, 1554 Hct. See Hematocrit (Hct) disseminated intravascular coagulation
gene mutations, 232t, 1494t, 1554 HCT. See Hematopoietic cell transplantation and, 2211
laboratory features, 1555 (HCT) eclampsia and, 122
blood, 1089, 1555 HCV infection. See Hepatitis C virus (HCV) epidemiology, 801, 2211
histopathology, 1494t infection etiology and pathophysiology, 801–802,
immunophenotypic profile, 1555, 1556f HDAC inhibitors. See Histone deacetylase 2211
marrow, 31–32, 1555, 1557f (HDAC) inhibitors folic acid deficiency and, 599
monocytopenia, 1098 HDACs (histone deacetylases), 239–240, laboratory features, 802
treatment, 1557–1559, 1559t 239t, 240f thrombocytopenia in, 2012
followup care, 1558–1559 HDFN. See Alloimmune hemolytic disease of treatment, 802–803, 2012, 2211
initiation, 1557 the fetus and newborn (HDFN) Helmet cells. See Schizocytes (schistocytes)
minimal residual disease, 1558 HDL. See High-density lipoprotein (HDL) Helminths
at relapse, 1559 HDL2 (Huntington disease-like 2) disorder, as cause of eosinophilia, 956–957, 957t
standard approach, 1557–1559 682 eosinophils and inactivation of, 952
variant (HCL-v), 1495t, 1554, 1555, 1558t HE. See Hereditary elliptocytosis (HE) Helper T cells. See CD4+ T cells (helper
von Willebrand disease and, 2082 Headache T cells)

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