Page 2511 - Williams Hematology ( PDFDrive )

2482 Index Index 2483

Pregnancy, 119–126 postpartum hemorrhage and, 1987, 2137, heart, 1581
acute fatty liver of, 2012, 2211 2138 paranasal sinuses, 1581
acute intermittent porphyria and, 901 preeclampsia in, 2011–2012, 2210–2211 skin, 1581
acute myelogenous leukemia during, 1409 Rh blood groups and, 2336 spleen, 1582
adaptations to, 119 sepsis during, 2211 Primary mediastinal large B-cell lymphoma,
alloimmunized, 849, 853f. See also sickle cell disease and, 772–773 1634–1635
Alloimmune hemolytic disease of thalassemia syndromes in, 126 clinical features, 1634
the fetus and newborn (HDFN) thrombocytopenia during, 121–122, definition, 1634
anemia in, 120 2010–2012, 2010t epidemiology, 1634
anticoagulant therapy during, 112, 112t, thrombophilia in, 122–123, 2221, 2225t, gene mutations, 225t, 1496t, 1597f, 1626
2277 2227 laboratory features, 1496t, 1596, 1596f,
antiphospholipid syndrome in, 2239, 2244, thrombophilia testing in, 2228t, 2229 1634
2245 thrombotic microangiopathy in, 2262 therapy, 1635
aplastic anemia and, 518 toxoplasmosis in, 1269 Primary myelofibrosis (PMF), 1319–1332
blood volume, erythropoietin level, and von Willebrand disease and, 121, 2176 clinical features, 1324–1325
hemoglobin concentration in, 119 warfarin therapy during, 112, 112t bone changes, 1325, 1325t
carbon monoxide poisoning in, 796 Pregnane X receptor, 893 extramedullary tumors, 1324
chemotherapy during, 124 Prekallikrein (PK), 1929, 2121 immune and inflammatory, 1325
chronic myelogenous leukemia during, Preleukemic anemia, 1342 portal hypertension and varices and
1459–1460 Preleukemic stem cells, 1376 pulmonary arterial hypertension,
coagulation factor deficiencies and, 121, Prenatal diagnosis/testing 1324–1325
2135, 2141, 2144 for hemophilia A, 2116 prefibrotic stage, 1323t, 1324
cobalamin deficiency in, 598 for hemophilia B, 2127 presenting signs, 1324
congenital thrombotic thrombocytopenic for thalassemias, 754 presenting symptoms, 1324
purpura in, 2257–2258 for von Willebrand disease, 2174 thrombocytosis, 1311
disseminated intravascular coagulation Prepromultimerin, 1845 thrombosis and bleeding, 2079–2081
during, 120–121, 2204t, Presenilin, 1013 thrombosis and hemorrhage, 1325
2210–2211 Preventive hematology, 7 course and prognosis, 1278, 1331–1332
essential thrombocythemia and, 124–125, Priapism, 770 definition and history, 1319
1314–1315, 2081 Primary adrenal lymphoma, 1583 differential diagnosis, 1311, 1327–1328,
factor V deficiency in, 2138 Primary autoimmune myelofibrosis, 1327 1449–1450
fibrinogen abnormalities in, 2155, 2156, Primary central nervous system lymphoma, epidemiology, 1319–1320
2159 1244f, 1246, 1579 essential thrombocythemia and, 1312–
fibrinolytic activity during, 2312 Primary cutaneous anaplastic large cell 1313
folate requirements/deficiency in, 120, 584, lymphoma, 1499t, 1687, 1688, etiology and pathogenesis, 1320–1323
597–598, 599 1688f CD34+ cell egress and neoplastic
HELLP syndrome in. See HELLP Primary cutaneous diffuse large B-cell megakaryocytopoiesis, 1321
syndrome lymphoma, leg type, 1637 chromosomal abnormalities, 178, 179t
hematologic consultation in, 45–46 Primary cutaneous follicular center clonal myeloid disease, animal models,
hematologic malignancies in, treatment of, lymphoma (PCFCL), 184t, 1581 and activating mutations, 1320–
123–124 Primary cutaneous marginal zone B-cell 1321
hemoglobinopathies in, 125–126 lymphoma (PCMZL), 184t, 1581 enhanced angiogenesis and splenic
heparin-induced thrombocytopenia in, Primary cutaneous peripheral T-cell endothelial cells, 1321
2032 lymphomas, 1499t exogenous factors, 1320
hereditary spherocytosis and, 674 Primary effusion lymphoma, 1246–1247, extramedullary hematopoiesis, 1278,
HIV infection in, 1269 1496t 1323
hypertension during, neonatal neutropenia Primary extranodal lymphoma, 1579–1583 fibroplasia, 1322–1323, 1322t
and, 994 bone, 1583 gene mutations, 228–229t, 1278, 1308t,
inherited platelet disorders in, 2062 breast, 1583 1320–1321
iron deficiency in, 120, 630 central nervous system, 1244f, 1246, 1579 hematopoietic dysfunction, 1321–1322
lymphoma treatment during, 1634 chest and lung, 1581 immune mechanisms, 1320
mononucleosis in, 1269 endocrine glands, 1583 laboratory features, 1325–1327
paroxysmal nocturnal hemoglobinuria eye, 1574, 1579–1581 blood cell counts and morphology,
and, 580 gastrointestinal tract, 1581 1323f, 1323t, 1325–1326
parvovirus B19 infection in, 849 genitourinary, 1246, 1581–1582, 1582f, functional abnormalities of blood cells,
polycythemia vera in, 125, 2081 1634 1326

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