Page 636 - Williams Hematology ( PDFDrive )

610 Part VI: The Erythrocyte Chapter 41: Folate, Cobalamin, and Megaloblastic Anemias 611

157. Lawler S, Roberts P, Hoffbrand A: Chromosome studies in megaloblastic anaemia 193. Halsted C, Reisenauer A, Romero J, et al: Jejunal perfusion of simple and conjugated
before and after treatment. Scand J Haematol 8(4):309–320, 1971. folates in celiac sprue. J Clin Invest 59(5):933–940, 1977.
158. Bessman J, Williams L, Gilmer PJ: Platelet size in health and hematologic disease. Am J 194. Hjelt K, Krasilnikoff P: The impact of gluten on haematological status, dietary intakes
Clin Pathol 78(2):150–153, 1982. of haemopoietic nutrients and vitamin B12 and folic acid absorption in children with
159. Marsh GW, Stewart JS: Splenic function in adult coeliac disease. Br J Haematol coeliac disease. Acta Paediatr Scand 79(10):911–919, 1990.
19(4):445–457, 1970. 195. Klipstein F: Tropical sprue in New York City. Gastroenterology 47:457–470, 1964.
160. Fudenberg H, Estren S: Non-addisonian megaloblastic anemia; the intermediate 196. Klipstein F, Schenk E, Samloff I: Folate repletion associated with oral tetracycline ther-
megaloblast in the differential diagnosis of pernicious and related anemias. Am J Med apy in tropical sprue. Gastroenterology 51(3):317–332, 1966.
25(2):198–209, 1958. 197. Klipstein F: Progress in gastroenterology: Tropical sprue. Gastroenterology 275, 1968.
161. Gulley M, Bentley S, Ross D: Neutrophil myeloperoxidase measurement uncovers 198. Sheehy T, Perez-Santiago E, Rubini M: Tropical sprue and vitamin B12. N Engl J Med
masked megaloblastic anemia. Blood 76(5):1004–1007, 1990. 265:1232–1236, 1961.
162. Solanki DL, Jacobson RJ, McKibbon J, Green R: Racial patterns in pernicious anemia. 199. Klipstein F: Folate in tropical sprue. Br J Haematol 23: Suppl:119–133, 1972.
N Engl J Med 298(24):1365. 200. Corcino J, Coll G, Klipstein F: Pteroylglutamic acid malabsorption in tropical sprue.
163. Solanki D, Jacobson R, Green R, et al: Pernicious anemia in blacks. A study of 64 Blood 45(4):577–580, 1975.
patients from Washington, D.C., and Johannesburg, South Africa. Am J Clin Pathol 201. Chanarin I, Bennett M: Absorption of folic acid and D-xylose as tests of small-intestinal
1981;75(1):96–99, 1978. function. Br Med J 1(5283):985–989, 1962.
164. Harper JW, Holleran SF, Ramakrishnan R, et al: Anemia in celiac disease is multifacto- 202. Booth C: The metabolic effects of intestinal resection in man. Postgrad Med J 37:
rial in etiology. Am J Hematol 82(11):996–1000, 2007. 725–739, 1961.
165. Green R: Anemias beyond B12 and iron deficiency: The buzz about other B’s, ele- 203. Pitney W, Joske R, Mackinnon N: Folic acid and other absorption tests in lympho-
mentary, and nonelementary problems. Hematology Am Soc Hematol Educ Program sarcoma, chronic lymphocytic leukaemia, and some related conditions. J Clin Pathol
2012:492–498, 2012. 13:440–447, 1960.
166. Bunn HF: Vitamin B12 and pernicious anemia—The dawn of molecular medicine. 204. Hoskins L, Norris H, Gottlieb L, Zamcheck N: Functional and morphologic alterations
N Engl J Med 370(8):773–776, 2014. of the gastrointestinal tract in progressive systemic sclerosis (scleroderma). Am J Med
167. Hershko C, Ronson A, Souroujon M, et al: Variable hematologic presentation of auto- 33:459–470, 1962.
immune gastritis: Age-related progression from iron deficiency to cobalamin depletion. 205. Vinnik I, Kern FJ, Struthers JJ: Malabsorption and the diarrhea of diabetes mellitus.
Blood 107(4):1673–1679, 2006. Gastroenterology 43:507–520, 1962.
168. Boddington M, Spriggs A: The epithelial cells in megaloblastic anaemias. J Clin Pathol 206. Cook G, Morgan J, Hoffbrand A: Impairment of folate absorption by systemic bacterial
12(3):228–234, 1959. infections. Lancet 2(7894):1416–1417, 1974.
169. Hussein S, Laulicht M, Hoffbrand A: Serum ferritin in megaloblastic anaemia. Scand J 207. Shojania AM: Folic acid and vitamin B12 deficiency in pregnancy and in the neonatal
Haematol 20(3):241–245, 1978. period. Clin Perinatol 11(2):433–459, 1984.
170. Emerson P, Wilkinson J: Lactate dehydrogenase in the diagnosis and assessment of 208. Landon M, Eyre D, Hytten F: Transfer of folate to the fetus. Br J Obstet Gynaecol
response to treatment of megaloblastic anaemia. Br J Haematol 12(6):678–688, 1966. 82(1):12–19, 1975.
171. Winston R, Warburton F, Stott A: Enzymatic diagnosis of megaloblastic anaemia. Br J 209. Pritchard J, Scott D, Whalley P, Haling RJ: Infants of mothers with megaloblastic ane-
Haematol 19(5):587–592, 1970. mia due to folate deficiency. JAMA 211(12):1982–1984, 1970.
172. Hansen N, Karle H: Blood and bone-marrow lysozyme in neutropenia: An attempt 210. Shapiro J, Alberts H, Welch P, Metz J: Folate and vitamin B-12 deficiency associated
towards pathogenetic classification. Br J Haematol 21(3):261–270, 1971. with lactation. Br J Haematol 11:498–504, 1965.
173. Heller P, Weinstein H, West M, Zimmerman H: Enzymes in anemia: A study of abnor- 211. Streiff R, Little A: Folic acid deficiency in pregnancy. N Engl J Med 276(14):776–779,
malities of several enzymes of carbohydrate metabolism in the plasma and erythrocytes 1967.
in patients with anemia, with preliminary observations of bone marrow enzymes. Ann 212. de Benoist B. Conclusions of a WHO Technical Consultation on folate and vitamin B12
Intern Med 53:898–913, 1960. deficiencies. Food Nutr Bull 29(2 Suppl):S238–S244, 2008.
174. de Klerk G, Rosengarten P, Vet R, Goudsmit R: Serum erythropoietin (ESF) titers in 213. Chanarin I, McFadyen I, Kyle R: The physiological macrocytosis of pregnancy. Br J
polycythemia. Blood 58(6):1171–1174, 1981. Obstet Gynaecol 84(7):504–508, 1977.
175. Myhre E: Studies on the erythrokinetics in pernicious anemia. Scand J Clin Lab Invest 214. Avery B, Ledger W: Folic acid metabolism in well-nourished pregnant women. Obstet
16:391–402, 1964. Gynecol 35(4):616–624, 1970.
176. Lindahl J: Quantification of ineffective erythropoiesis in megaloblastic anaemia by 215. Giles C: An account of 335 cases of megaloblastic anaemia of pregnancy and the puer-
determination of endogenous production of 14CO after administration of glycine- perium. J Clin Pathol 19(1):1–11, 1966.
2–14C. Scand J Haematol 24(4):281–291, 1980. 216. Lindenbaum J, Klipstein F: Folic acid deficiency in sickle-cell anemia. N Engl J Med
177. Hamililton H, Sheets R, DeGowin E: Studies with inagglutinable erythrocyte counts. 269:875–882, 1963.
VII. Further investigation of the hemolytic mechanism in untreated pernicious ane- 217. Hild D: Folate losses from the skin in exfoliative dermatitis. Arch Intern Med 123(1):
mia and the demonstration of a hemolytic property in the plasma. J Lab Clin Med 51–57, 1969.
51(6):942–955, 1958. 218. Whitehead V, Comty C, Posen G, Kaye M: Homeostasis of folic acid in patients under-
178. Harker L, Finch C: Thrombokinetics in man. J Clin Invest 48(6):963–974, 1969. going maintenance hemodialysis. N Engl J Med 279(18):970–974, 1968.
179. Obeid R, Geisel J, Schorr H, et al: The impact of vegetarianism on some haematological 219. Green R: Metabolite assays in cobalamin and folate deficiency. Baillieres Clin Haematol
parameters. Eur J Haematol 69(5–6):275–279, 2002. 8(3):533–566, 1995.
180. Jacques P, Selhub J, Bostom A, et al: The effect of folic acid fortification on plasma folate 220. Hoffbrand A, Newcombe F, Mollin D: Method of assay of red cell folate activity and the
and total homocysteine concentrations. N Engl J Med 340(19):1449–1454, 1999. value of the assay as a test for folate deficiency. J Clin Pathol 19(1):17–28, 1966.
181. Ballard H, Lindenbaum J: Megaloblastic anemia complicating hyperalimentation ther- 221. Lindenbaum J: Status of laboratory testing in the diagnosis of megaloblastic anemia.
apy. Am J Med 56(5):740–742, 1974. Blood 61(4):624–627, 1983.
182. Mollin D, Hines J: Late post-gastrectomy syndromes. observations on the nature and 222. McNamee T, Hyland T, Harrington J, et al: Haematinic deficiency and macrocytosis in
pathogenesis of anaemia following partial gastrectomy. Proc R Soc Med 57:575–580, middle-aged and older adults. PLoS One 8(11):E77743, 2013.
1964. 223. Leffler DA, Schuppan D: Update on serologic testing in celiac disease. Am J Gas-
183. Hoffbrand A: Folate deficiency in premature infants. Arch Dis Child 45(242):441–444, troenterol 2010;105(12):2520–2524, 2013.
1970. 224. Kinnear D, Macintosh P, Cameron D, et al: Intestinal absorption of tritium-labelled
184. Royston NJ, Parry TE: Megaloblastic anaemia complicating dietary treatment of phe- folic acid in idiopathic steatorrhea: Effect of a gluten-free diet. Can Med Assoc J 89:
nylketonuria in infancy. Arch Dis Child 37(194):430–435, 1962. 975–979, 1963.
185. Ford JD, Scott KJ: The folic acid activity of some milk foods for babies. J Dairy Res 225. Green R, Miller JW: Folate deficiency beyond megaloblastic anemia: Hyperhomo-
35:85, 1968. cysteinemia and other manifestations of dysfunctional folate status. Semin Hematol
186. Savage D, Lindenbaum J: Anemia in alcoholics. Medicine (Baltimore) 65(5):322–338, 36(1):47–64, 1999.
1986. 226. Prevention of neural tube defects: Results of the Medical Research Council Vitamin
187. Eichner E, Hillman R: Effect of alcohol on serum folate level. J Clin Invest 52(3): Study. MRC Vitamin Study Research Group. Lancet 338(8760):131–137, 1991.
584–591, 1973. 227. Rothenberg S, da Costa M, Sequeira J, et al: Autoantibodies against folate recep-
188. Lieber C: Metabolism and metabolic effects of alcohol. Semin Hematol 17(2):85–99, tors in women with a pregnancy complicated by a neural-tube defect. N Engl J Med
1980. 350(2):134–142, 2004.
189. Post R, Desforges J: Thrombocytopenia and alcoholism. Ann Intern Med 68(6): 228. van der Put N, Gabreëls F, Stevens E, et al: A second common mutation in the meth-
1230–1236, 1968. ylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
190. Liu Y: Effects of alcohol on granulocytes and lymphocytes. Semin Hematol 17(2): Am J Hum Genet 62(5):1044–1051, 1998.
130–136, 1980. 229. Honein M, Paulozzi L, Mathews T, et al: Impact of folic acid fortification of the US food
191. Lindenbaum J, Lieber C: Hematologic effects of alcohol in man in the absence of nutri- supply on the occurrence of neural tube defects. JAMA 285(23):2981–2986, 2001.
tional deficiency. N Engl J Med 281(7):333–338, 1969. 230. De Wals P, Tairou F, Van Allen M, et al: Reduction in neural-tube defects after folic acid
192. Trier J: Celiac sprue. N Engl J Med 325(24):1709–1719, 1991. fortification in Canada. N Engl J Med 357(2):135–142, 2007.

Kaushansky_chapter 41_p0583-0616.indd 611 9/17/15 6:24 PM