Page 1266 - Clinical Immunology_ Principles and Practice ( PDFDrive )
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CHaPter 90  Vaccines         1226.e1


              MUL t IPL e -CHOIC e  QU e S t IO n S

           1.  The physician often recognized as the “father of vaccinology”   recommendations for each vaccine based on the age of the
             is:                                                    patient, and other indications. In the 2017 schedule, these
              A. James Phipps                                       included:
              B. Robert Koch                                         A. All adults (persons ≥19 years of age) should receive annual
              C. Edward Jenner                                         influenza vaccination; a tetanus–diphtheria–acellular
              D. Louis Pasteur                                         pertussis (Tdap) vaccine once, followed by tetanus boosters
                                                                       every 10 years; zoster vaccination at 60 years of age; and
           2.  The polysaccharide vaccines developed for the prevention of
             bacterial diseases caused by pathogenic organisms, such as   pneumococcal vaccination at 65 years of age.
             Haemophilus influenzae, Neisseria meningitidis, and Streptococ-   B. Other vaccines indicated for certain risk factors, including
             cus pneumoniae, became much more useful upon conjugation   medical conditions (e.g., immunocompromising conditions,
             with:                                                     kidney failure, diabetes) or life style, occupational, or other
              A. Lipids                                                conditions (e.g., pregnancy, men who have sex with men,
              B. Small molecule metabolites                            health care personnel).
              C. Proteins                                            C. Live vaccines (varicella, zoster, and measles–mumps–rubella
              D. Polymers                                              [MMR]) are contraindicated for pregnant women,
                                                                       immunocompromised hosts, and in those with human
           3.  The  Advisory Committee on Immunization Practices       immunodeficiency virus [HIV] infection when the CD4+
             (ACIP) of the US Centers for Disease Control and Prevention   T-cell absolute count is below 200 cells/µL.
             (CDC) in its adult immunization schedule makes annual    D. All of the above are correct.
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