Page 291 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPTEr 18 Regulatory Immune Cells 271.e1

MULTIPLE-CHOICE QUESTIONS

1. What are the symptoms of loss of FOXP3 function? 3. What is the primary suppressive mechanism used by Tr1 cells?
A. Inflammatory bowel disease A. Granzyme B
B. Allergic disease (allergic dermatitis, food allergy, hyperim- B. IL-35
munoglobulinemia E) C. CTLA-4
C. Type 1 diabetes D. IL-10
D. All of the above
4. What extracellular marker is most commonly used to identify
+
+
+
+
2. A cell is Helios Neuropilin Foxp3 CD4 . What is it most Foxp3 expressing Tregs?
likely to be? A. CD27
A. tTreg B. CD69
B. pTreg C. CD25
C. iTreg D. CD28
D. Tr1