Page 180 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )
P. 180

Normal reference ranges and variations                                                                        Explain the physiological events that alter the number of circulating


               ■    List the normal relative reference values for neutrophils, eosino-                                         granulocytes and monocytes in the peripheral blood.

                   phils, and basophils and monocytes in normal peripheral blood.                                            Describe how neutrophils exit the peripheral blood circulation and

               ■    State the (neutrophilic) granulocyte reference range.                                                      migrate to the site of an infection or injury.

               ■    State the normal relative reference range for monocytes.                                                 Discuss the specialized functions of eosinophils and basophils.

               ■    Describe ethnic differences and daily   uctuation of granulocytes.                                       Compare  differences  in  phagocytosis  by  monocytes  versus
                                                                                                                               neutrophils.

               Functional properties of monocytes/                                                                           De  ne the abbreviation, NETS, and brie  y describe.

               macrophages                                                                                                 Case study


                 Explain the function of monocytes/macrophages.                                                              Analyze the patient history, clinical signs and symptoms, and labo-


               ■    Describe the general function of monocytes                                                                 ratory data for the stated case studies, answer the related critical
                 Compare the phenotypic differences of the three subsets of mono-                                              thinking questions, and conclude the most likely diagnosis.

                   cytes in the circulating blood.




               Phagocytosis                                                                                                   NOTE:

                 Explain  the  general  characteristics  and  specific  details  of                                           ■   Indicates MLT and MLS core content

                   phagocytosis.                                                                                                Indicates MLT (optional) and MLS advanced content












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               IN  RODUC  ION
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               T                     m                                                     m        m-                                                     m                                            . C

               m    , m                        m                       . T

                                m                     . S       q        m                        -

                                                       m  j                                                -                    BOX  8.1

               m                                            :                           ,      k          ,

                           m            .

                    L    k                                                                                                    The Immune System

                                                    , m            -m               ,           m-

                          -     m         . T                                                                                 NATURAL IMMUNE SYSTEM

                    k          ,                                                                            ,                 Cellular

                               ,               ,             m              -m                         .                      ■   M

                    E           k                                       q                                                     ■   N

                                                    ,     m               ,                                                   ■   M

                                      . T        m                                                   m  -

                                                    (PMN)       k                          m      -                           Humoral

                           m              /m                 .  T                                                             ■   C  m     m

                                                    “       -    k”    m        m                                             ■   L     z  m

                mm              m (      B  x   .  ),                m                  ,                                     ■   I

                    ,        CD         m              . L  m              (    C           )                                 ADAPTIVE IMMUNE SYSTEM

                                                             m

                                                                                   . P    m                                   Cellular

                                                                       m  j                 .                                 ■        m
                                                                                                                              ■   B    m

                                                                                                                              ■   P    m

               GRANULOCY  IC SERIES: PRODUC  ION                                                                              Humoral
               OF NEU  ROPHILS, EOSINOPHILS, AND                                                                                  A


               BASOPHILS                                                                                                      ■
                                                                                                                              ■   C     k

               T                m                                m     m                     m                                Cell-Mediated Immunity

                                  m                   m     x                                                                 ■        m

               m                  m                               m           ,        k      ,                               ■   D              -   -

                        x                 m     x. C     k        m               mm

                                                   x                                             m                            ■   D                                                                ,                -

                                                          x                                                 -                                      m ,    m                 ,                           j

                           . T                                                                      m        ,
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